XBI State Street SPDR S&P Biotech ETF
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Over the year to Oct 28, 2026, XBI returned 41.2%.
Promise check: Not measuredIts theme exposure is measured once ETFIQ defines its theme company by company.
XBI risk and return scorecard
vs its own holdings
Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data
Money in and out
Net fund flows · Oct 22, 2026What you earned
What did you actually buy?
Biotech · holdings as of Oct 27, 2026More on XBI
Every number below is on this page. Open what you need.Price, 1 year
$157.51+1.7%1 day, priceClose, Oct 28, 2026
Price only. Total return over the same days, distributions reinvested, was +41.2%. Computed by ETFIQ from Tiingo daily prices.
Source: Tiingo end-of-day prices. Data as of Oct 28, 2026. Updated every trading night. Report a data error
| Window | Total return | S&P 500 (SPY) |
|---|---|---|
| 1M Sep 28 – Oct 28, 2026 | +0.6% | +0.9% |
| 3M Jul 29 – Oct 28, 2026 | +6.5% | +6.1% |
| 6M Apr 29 – Oct 28, 2026 | +22.3% | +9.1% |
| YTD Dec 31, 2025 – Oct 28, 2026 | +29.3% | +14.1% |
| 1Y Oct 28, 2025 – Oct 28, 2026 | +41.2% | +13.6% |
| 3Y Oct 27, 2023 – Oct 28, 2026 | +147.2% | +95.0% |
| 5Y Oct 29, 2021 – Oct 28, 2026 | +27.0% | +79.8% |
| 10Y Oct 28, 2016 – Oct 28, 2026 | +181.0% | +325.8% |
| Since launch Feb 6, 2006 – Oct 28, 2026 | +914.8% | +791.2% |
| Since launch, annualised Feb 6, 2006 – Oct 28, 2026 | +11.8% | – |
Total returns, distributions reinvested.
Source: Tiingo end-of-day prices, with distributions reinvested.
Money in and out
Daily data · as of Oct 22, 2026XBI: in the year to Oct 22, 2026, net $1.4bn came in; in the month to Oct 22, 2026, $576m came in.
Oct 21, 2026 to Oct 22, 2026
Sep 28, 2026 to Oct 22, 2026
Jul 28, 2026 to Oct 22, 2026
Jan 2, 2026 to Oct 22, 2026
Oct 28, 2025 to Oct 22, 2026
round trip, net −$73.1m
SEC filings, then daily counts
XBI, net flow each trading day over the 62 sessions from Jul 28, 2026 to Oct 22, 2026: money came in on 35 days and went out on 27 days.
Money in on 35 of the 62 trading days, out on 27.
XBI, net flow each trading day over the 248 sessions from Oct 28, 2025 to Oct 22, 2026: money came in on 124 days and went out on 124 days.
Money in on 124 of the 248 trading days, out on 124.
XBI, net flow each trading day over the 400 sessions from Mar 21, 2025 to Oct 22, 2026: money came in on 186 days and went out on 211 days.
Money in on 186 of the 400 trading days, out on 211.
Computed by ETFIQ from State Street’s daily data: each day’s change in shares outstanding times the previous day’s net asset value. Round trips: $487m came in on Nov 25, 2025 and $560m went out on Dec 2, 2025. A creation undone within days moves money in and straight back out, so it says little about what investors wanted. Both days stay in every total and are marked in the tables and the drawings.
How this is computed
Percentages are of net assets at the start of each window. Numbers are net: money in less money out. Checked against the filing: The month’s daily sum and the filing’s B.6 number agree within rounding or, where the filing’s is larger, within rounding plus the fund’s creation and redemption fees. The full rule is in the fund’s flows file. Every day and month ETFIQ holds for XBI, back to Jul 2019, is in its flows file. Flows across every fund · How these flows are computed · Compare XBI with other funds in the flows tool
Every trading day, last 3 months62 days
Most recent first.
Week by week, last year52 weeks
Net flow into XBI each week, Oct 28, 2025 to Oct 22, 2026, most recent first, each week named by its last trading day with data. Computed by ETFIQ.
Month by month, money in and money outNov 2023 to Oct 2026
XBI, money in and money out each month from Nov 2023 to Sep 2026: two bars a month, money in above the line and money out below. Bars for Nov 2023 to Jun 2026 are from XBI’s SEC filings (N-PORT item B.6), and for Jul 2026 to Sep 2026 ETFIQ’s sums of its days. Oct 2026 is still in progress, so it is in the list and not drawn. Of the 36 months listed, money came in on net in 15 and went out in 21.
Bars for Nov 2023 to Jun 2026 are from XBI’s SEC filings (N-PORT item B.6), and for Jul 2026 to Sep 2026 ETFIQ’s sums of its days. Of the 36 months listed, money came in on net in 15 and went out in 21.
Most recent first.
How this is computed
N-PORT months: money in is sales plus reinvestments; money out is redemptions. Months summed from daily data: money in adds the days money came in; money out adds the days it went out.
N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.
Source: ETFIQ, from the fund’s daily share counts and net asset values, and its SEC N-PORT filings. Data as of Oct 22, 2026.
XBI key stats
Trading
as of Oct 27, 2026
XBI top ten by weight, 17.8% of the fund, of its 165 equity positions, from the holdings published by its issuer for Oct 27, 2026. Source: the issuer’s own daily file.
Source: State Street’s daily holdings file. Data as of Oct 27, 2026. Updated each trading day. Last checked Oct 28, 2026.
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About XBI
How we measure
12 seats on XBI, as of Oct 28, 2026: 1 Supports, 1 Mixed, 5 Challenges, 5 Not enough data.
Questions people ask about XBI
- How much of XBI is in S&P 500 companies?
- By its holdings published by its issuer for Oct 27, 2026, 13% of XBI by weight is stocks the S&P 500 already holds. Its active share against the index is 98%, so that share is the part doing something different.
- What does XBI hold?
- 165 positions as published by its issuer for Oct 27, 2026, with the top ten at 18% of the fund. The largest are MODERNA INC at 2.2%, TWIST BIOSCIENCE CORP at 1.9%, NATERA INC at 1.8%.
- Has XBI beaten the S&P 500?
- Over the year to Oct 28, 2026 XBI returned +41.2% with distributions reinvested, against +13.6% for the S&P 500, so it finished ahead of the index by 27.6 points.
- What does XBI cost?
- The prospectus expense ratio is 0.35% a year. Because 98% of the fund differs from the S&P 500, the fee on that differing part works out at 0.36%.
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ETFIQ, XBI, thematic ETFs, data as of Oct 28, 2026. https://etfiq.com/funds/xbi
ETFIQ. (Oct 28, 2026). XBI, thematic ETFs. Retrieved from https://etfiq.com/funds/xbi
[XBI, thematic ETFs (ETFIQ, Oct 28, 2026)](https://etfiq.com/funds/xbi)
The difference bar for XBI, redrawn every trading night.
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<figure style="margin:0;max-width:640px">
<a href="https://etfiq.com/funds/xbi"><img src="https://etfiq.com/assistant/api/embed/themes/xbi.svg" alt="XBI: 13% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 27, 2026." width="640" style="max-width:100%;height:auto"></a>
<figcaption style="font:13px/1.5 sans-serif">XBI: 13% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 27, 2026. Data: <a href="https://etfiq.com/funds/xbi">ETFIQ</a></figcaption>
</figure>The day's ETF flows, a comparison and one number. Every trading morning. About the Daily
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