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Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

MGK vs XBI: how they differ

MGK and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

Vanguard Mega Cap Growth Index Fund and State Street(R) SPDR(R) S&P(R) Biotech ETF.

What they hold in common

By the books each fund has filed, MGK and XBI hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in MGKOnly in XBI
NVIDIA Corp 13.29%MODERNA INC 2.87%
Apple Inc 12.19%TWIST BIOSCIENCE CORP 1.81%
Microsoft Corp 7.52%HALOZYME THERAPEUTICS INC 1.47%
Alphabet Inc 5.93%NATERA INC 1.46%
Alphabet Inc 4.67%KYMERA THERAPEUTICS INC 1.45%
Amazon.com Inc 4.47%TRAVERE THERAPEUTICS INC 1.40%
Broadcom Inc 4.28%ROIVANT SCIENCES LTD 1.39%
Meta Platforms Inc 4.08%ORUKA THERAPEUTICS INC 1.38%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jun 30, 2026 and Sep 10, 2026.

MGK and XBI on the fields both publish, as of Sep 13, 2026. Source: ETFIQ.
MGK
Vanguard Mega Cap Growth Index Fund
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF
Where it sitsCore index fundCore index fund
IssuerVanguardState Street
What it isMega Cap GrowthSPDR S&P Biotech
Total return, 1 year+14.9%+64.0%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500−2.6 pts+46.5 pts
Expense ratio0.07%0.35%
Already in the S&P 50099.2%8.5%
Holdings56154

MGK in plain words

MGK is an index equity fund tracking the Mega Cap Growth. Over the year to Sep 11, 2026 it returned +14.9% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.07% a year. By its holdings filed for Jun 30, 2026, 99% of the fund by weight is stocks the S&P 500 also holds, across 56 positions, with the top ten at 63.8%.

XBI in plain words

XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, MGK or XBI?
In the year to Sep 13, 2026, with distributions reinvested, MGK returned +14.9% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
Which is cheaper, MGK or XBI?
MGK charges 0.07% a year and XBI charges 0.35%, so MGK is cheaper. Fees come from each fund's prospectus.
How much do MGK and XBI overlap with the S&P 500?
By their latest filed holdings, 99% of MGK and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

MGK against XBI, ETFIQ, data as of Sep 13, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, MGK against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/mgk-vs-xbi Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources