Data as of Oct 28, 2026.
USO vs XBI: Differences, Returns & Fees
Over the year to Oct 28, 2026, USO returned +133.3% to XBI's +41.2%, and XBI charges 0.35% to USO's 0.86%.
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askIQ about USO and XBINet assets: $1.9bn on Oct 28, 2026 for United States Oil Fund, LP, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.
Pair scorecard
XBI costs 0.51 points a year less; their one-year returns differ by 92.1 points; XBI is 5.4 times larger.
| Measure | USO | XBI |
|---|---|---|
| Return | ||
| Total return, 1 year | +133.3% | +41.2% |
| Drawdown | ||
| Below its high | 82.3%, high on Jul 14, 2008 | |
| Below its all-time high | 8.9%, high on Feb 8, 2021 | |
| Benchmark | ||
| What it tracks | Oil futures | Biotech |
| Cost and size | ||
| Expense ratio | 0.86% | 0.35% |
| Net assets, as of Oct 27, 2026 | $1.9bn | $10.3bn |
| Active share vs the S&P 500 | 98% | |
| Holdings | ||
| Holdings in common | not published | |
| In the S&P 500, by weight | 13% | |
| Top ten holdings, share of the fund | 18% | |
Side by side
USO and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.
USO
USO holds oil futures. Over the year to Oct 28, 2026 it returned +133.3% with distributions reinvested. The prospectus expense ratio is 0.86% a year. It sat 82.3% below its high of Jul 14, 2008 on Oct 28, 2026.
XBI
By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.
Questions people ask
- Are USO and XBI in the same category?
- USO is a commodity ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
- Which returned more over the last year, USO or XBI?
- In the year to Oct 28, 2026, with distributions reinvested, USO returned +133.3% and XBI +41.2%.
- Which is cheaper, USO or XBI?
- XBI is cheaper, by 0.51 percentage points a year. That is about $51 on $10,000 held for a year. Fees come from each fund's prospectus.
Links are sources, not endorsements. A comparison is not a recommendation.
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ETFIQ, USO against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/uso-vs-xbi
ETFIQ. (Oct 28, 2026). USO against XBI. Retrieved from https://etfiq.com/compare/any/uso-vs-xbi
[USO against XBI (ETFIQ, Oct 28, 2026)](https://etfiq.com/compare/any/uso-vs-xbi)
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