Data as of Oct 28, 2026.

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IBB vs USO: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to USO's +133.3%, and IBB charges 0.44% to USO's 0.86%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $1.9bn on Oct 28, 2026 for United States Oil Fund, LP.

At a glance
+37.5%
IBB total return, 1 year
+133.3%
USO total return, 1 year
0.44%
IBB expense ratio
0.86%
USO expense ratio

Pair scorecard

IBB costs 0.42 points a year less; their one-year returns differ by 95.8 points; IBB is 5.8 times larger.

IBB vs USO: Differences, Returns & Fees
MeasureIBBUSO
Return
Total return, 1 year+37.5%+133.3%
Drawdown
Below its high82.3%, high on Jul 14, 2008
Benchmark
What it tracksBiotechOil futures
Cost and size
Expense ratio0.44%0.86%
Net assets, as of Oct 27, 2026$11.0bn$1.9bn
Active share vs the S&P 50099%
Holdings
Holdings in commonnot published
In the S&P 500, by weight40%
Top ten holdings, share of the fund50%

Method

Risk and return

Apr 21, 2006 to Oct 23, 2026 · 1,070 weekly returns
IBB USO
Return
Total return edge IBB +735.5% −70.9%
Annualized edge IBB +10.9% −5.8%
Price return edge IBB +699.8% −70.9%
Risk
Volatility edge IBB 22.7% 37.1%
Max drawdown edge IBB −37.5% −98.0%
Risk-adjusted
Sharpe edge IBB 0.49 −0.02
Sortino edge IBB 0.71 −0.03
Calmar edge IBB 0.29 −0.06
Reading

IBB returned more: +735.5% to −70.9%. IBB swung less: 22.7% to 37.1%. IBB fell less at its worst: −37.5% to −98.0%.

Full scorecard

9 measures, with how each is measured
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Risk and return: IBB vs USO: Differences, Returns & Fees
MeasureIBBUSOEdgeHow it is measured
Return
Total return+735.5%−70.9%IBBPrice change plus distributions, reinvested.
Annualized+10.9%−5.8%IBBTotal return as a yearly rate.
Price return+699.8%−70.9%IBBPrice change alone, distributions left out.
Risk
Volatility22.7%37.1%IBBSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.9%26.9%IBBLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.5%−98.0%IBBDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.49−0.02IBBReturn above Treasury bills per unit of volatility.
Sortino0.71−0.03IBBReturn above Treasury bills per unit of downside deviation.
Calmar0.29−0.06IBBAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,070 weekly returns. Cash rate: the 13-week Treasury bill.

Side by side

IBB iShares Biotechnology ETF USO United States Oil Fund, LP
Where it sits Thematic ETF Commodity ETF
Issuer iShares USCF
What it is Biotech Holds oil futures
Total return, 1 year +37.5% +133.3%
Expense ratio 0.44% 0.86%
Holdings 245 not counted
Net assets, IBB as of Oct 27, 2026 and USO as of Oct 28, 2026 $11.0bn $1.9bn

IBB and USO on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-E7CF7217F8

IBB and USO do different jobs. What does each one do in a portfolio?

  1. What each follows. IBB follows Biotech and USO follows Oil futures.
  2. One-year total return. Over 1 year to Oct 28, 2026 IBB returned +37.5% and USO +133.3% with distributions reinvested, a gap of 95.8 points.
  3. Cost. IBB charges 0.44% of assets a year and USO 0.86%, a gap of 0.42 points.

Data as of Oct 28, 2026.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

USO

USO holds oil futures. Over the year to Oct 28, 2026 it returned +133.3% with distributions reinvested. The prospectus expense ratio is 0.86% a year. It sat 82.3% below its high of Jul 14, 2008 on Oct 28, 2026.

Questions people ask

Are IBB and USO in the same category?
IBB is a thematic ETF and USO is a commodity ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or USO?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and USO +133.3%.
Which is cheaper, IBB or USO?
IBB is cheaper, by 0.42 percentage points a year. That is about $42 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, IBB against USO, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-uso

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.