Fund holdings · State Street(R) SPDR(R) S&P(R) Biotech ETF
XBI holdings: all 165 positions
XBI held 165 positions as of Oct 13, 2026. Moderna Inc is the largest at 2.46%; the top 10 are 17.7% of the fund.
Every position
150 of 165 · click a column to sort
| # | Holding | Ticker | Weight ↓ |
|---|---|---|---|
| 1 | Moderna Inc | MRNA | 2.46% |
| 2 | Twist Bioscience Corp | TWST | 1.86% |
| 3 | Natera Inc | NTRA | 1.85% |
| 4 | Iovance Biotherapeutics Inc | IOVA | 1.70% |
| 5 | AbbVie Inc | ABBV | 1.69% |
| 6 | Biogen Inc | BIIB | 1.68% |
| 7 | United Therapeutics Corp | UTHR | 1.66% |
| 8 | Amgen Inc | AMGN | 1.63% |
| 9 | Halozyme Therapeutics Inc | HALO | 1.57% |
| 10 | Exelixis Inc | EXEL | 1.57% |
| 11 | Gilead Sciences Inc | GILD | 1.57% |
| 12 | TG Therapeutics Inc | TGTX | 1.53% |
| 13 | Protagonist Therapeutics Inc | PTGX | 1.47% |
| 14 | Regeneron Pharmaceuticals Inc | REGN | 1.44% |
| 15 | Vertex Pharmaceuticals Inc | VRTX | 1.44% |
| 16 | GRAIL Inc | GRAL | 1.44% |
| 17 | Spyre Therapeutics Inc | SYRE | 1.43% |
| 18 | Krystal Biotech Inc | KRYS | 1.42% |
| 19 | CRISPR Therapeutics AG | CRSP | 1.42% |
| 20 | Revolution Medicines Inc | RVMD | 1.40% |
| 21 | Vaxcyte Inc | PCVX | 1.39% |
| 22 | PTC Therapeutics Inc | PTCT | 1.37% |
| 23 | Alkermes PLC | ALKS | 1.35% |
| 24 | Neurocrine Biosciences Inc | NBIX | 1.34% |
| 25 | Alnylam Pharmaceuticals Inc | ALNY | 1.34% |
| 26 | Incyte Corp | INCY | 1.33% |
| 27 | Oruka Therapeutics Inc | ORKA | 1.32% |
| 28 | BioMarin Pharmaceutical Inc | BMRN | 1.30% |
| 29 | Erasca Inc | ERAS | 1.29% |
| 30 | Bridgebio Pharma Inc | BBIO | 1.28% |
| 31 | Cytokinetics Inc | CYTK | 1.28% |
| 32 | Madrigal Pharmaceuticals Inc | MDGL | 1.28% |
| 33 | Roivant Sciences Ltd | ROIV | 1.23% |
| 34 | Kodiak Sciences Inc | KOD | 1.23% |
| 35 | Travere Therapeutics Inc | TVTX | 1.21% |
| 36 | ImmunityBio Inc | IBRX | 1.20% |
| 37 | Kymera Therapeutics Inc | KYMR | 1.19% |
| 38 | Ionis Pharmaceuticals Inc | IONS | 1.17% |
| 39 | Insmed Inc | INSM | 1.16% |
| 40 | Cogent Biosciences Inc | COGT | 1.15% |
| 41 | Dianthus Therapeutics Inc | DNTH | 1.12% |
| 42 | Praxis Precision Medicines Inc | PRAX | 1.09% |
| 43 | Arrowhead Pharmaceuticals Inc | ARWR | 1.09% |
| 44 | Rhythm Pharmaceuticals Inc | RYTM | 1.07% |
| 45 | Veracyte Inc | VCYT | 1.05% |
| 46 | Mirum Pharmaceuticals Inc | MIRM | 1.02% |
| 47 | CG oncology Inc | CGON | 1.00% |
| 48 | Viking Therapeutics Inc | VKTX | 0.96% |
| 49 | Tango Therapeutics Inc | TNGX | 0.94% |
| 50 | CareDx Inc | CDNA | 0.90% |
| 51 | Relay Therapeutics Inc | RLAY | 0.88% |
| 52 | Beam Therapeutics Inc | BEAM | 0.88% |
| 53 | Arcutis Biotherapeutics Inc | ARQT | 0.82% |
| 54 | Ultragenyx Pharmaceutical Inc | RARE | 0.79% |
| 55 | Celcuity Inc | CELC | 0.79% |
| 56 | Scholar Rock Holding Corp | SRRK | 0.77% |
| 57 | SELLAS Life Sciences Group Inc | SLS | 0.73% |
| 58 | Dyne Therapeutics Inc | DYN | 0.69% |
| 59 | Recursion Pharmaceuticals Inc | RXRX | 0.67% |
| 60 | Hyperliquid Strategies Inc | PURR | 0.64% |
| 61 | Immunovant Inc | IMVT | 0.63% |
| 62 | Novavax Inc | NVAX | 0.62% |
| 63 | Summit Therapeutics Inc | SMMT | 0.59% |
| 64 | Denali Therapeutics Inc | DNLI | 0.59% |
| 65 | BioCryst Pharmaceuticals Inc | BCRX | 0.58% |
| 66 | Ideaya Biosciences Inc | IDYA | 0.57% |
| 67 | Agios Pharmaceuticals Inc | AGIO | 0.54% |
| 68 | Intellia Therapeutics Inc | NTLA | 0.53% |
| 69 | Vera Therapeutics Inc | VERA | 0.51% |
| 70 | Sarepta Therapeutics Inc | SRPT | 0.51% |
| 71 | Nurix Therapeutics Inc | NRIX | 0.51% |
| 72 | ADMA Biologics Inc | ADMA | 0.49% |
| 73 | Arcus Biosciences Inc | RCUS | 0.49% |
| 74 | Palvella Therapeutics Inc | PVLA | 0.49% |
| 75 | ACADIA Pharmaceuticals Inc | ACAD | 0.48% |
| 76 | Viridian Therapeutics Inc | VRDN | 0.47% |
| 77 | Celldex Therapeutics Inc | CLDX | 0.47% |
| 78 | Absci Corp | ABSI | 0.47% |
| 79 | Vericel Corp | VCEL | 0.47% |
| 80 | uniQure NV | QURE | 0.45% |
| 81 | Precigen Inc | PGEN | 0.44% |
| 82 | Biohaven Ltd | BHVN | 0.44% |
| 83 | Disc Medicine Inc | IRON | 0.43% |
| 84 | Nektar Therapeutics | NKTR | 0.39% |
| 85 | Syndax Pharmaceuticals Inc | SNDX | 0.37% |
| 86 | Immunome Inc | IMNM | 0.36% |
| 87 | Mineralys Therapeutics Inc | MLYS | 0.32% |
| 88 | Xencor Inc | XNCR | 0.32% |
| 89 | Replimune Group Inc | REPL | 0.32% |
| 90 | Stoke Therapeutics Inc | STOK | 0.31% |
| 91 | AnaptysBio Inc | ANAB | 0.30% |
| 92 | Inhibrx Biosciences Inc | INBX | 0.29% |
| 93 | First Tracks Biotherapeutics Inc | TRAX | 0.29% |
| 94 | ORIC Pharmaceuticals Inc | ORIC | 0.29% |
| 95 | Vir Biotechnology Inc | VIR | 0.28% |
| 96 | Zenas Biopharma Inc | ZBIO | 0.27% |
| 97 | Kura Oncology Inc | KURA | 0.26% |
| 98 | Jade Biosciences Inc | JBIO | 0.24% |
| 99 | Ardelyx Inc | ARDX | 0.24% |
| 100 | Annexon Inc | ANNX | 0.23% |
| 101 | Rigel Pharmaceuticals Inc | RIGL | 0.23% |
| 102 | MannKind Corp | MNKD | 0.23% |
| 103 | Geron Corp | GERN | 0.23% |
| 104 | Tyra Biosciences Inc | TYRA | 0.22% |
| 105 | Monte Rosa Therapeutics Inc | GLUE | 0.22% |
| 106 | Vor BioPharma Inc | VOR | 0.22% |
| 107 | Candel Therapeutics Inc | CADL | 0.21% |
| 108 | Janux Therapeutics Inc | JANX | 0.20% |
| 109 | Bicara Therapeutics Inc | BCAX | 0.20% |
| 110 | Taysha Gene Therapies Inc | TSHA | 0.19% |
| 111 | Immix Biopharma Inc | IMMX | 0.19% |
| 112 | Avalo Therapeutics Inc | AVTX | 0.18% |
| 113 | Cullinan Therapeutics Inc | CGEM | 0.18% |
| 114 | Corvus Pharmaceuticals Inc | CRVS | 0.18% |
| 115 | Verastem Inc | VSTM | 0.17% |
| 116 | Hemab Therapeutics Holdings Inc | COAG | 0.16% |
| 117 | Savara Inc | SVRA | 0.16% |
| 118 | Olema Pharmaceuticals Inc | OLMA | 0.16% |
| 119 | ArriVent Biopharma Inc | AVBP | 0.15% |
| 120 | Achieve Life Sciences Inc | ACHV | 0.15% |
| 121 | 4D Molecular Therapeutics Inc | FDMT | 0.15% |
| 122 | REGENXBIO Inc | RGNX | 0.15% |
| 123 | Damora Therapeutics Inc | DMRA | 0.14% |
| 124 | Sana Biotechnology Inc | SANA | 0.14% |
| 125 | Kailera Therapeutics Inc | KLRA | 0.14% |
| 126 | Capricor Therapeutics Inc | CAPR | 0.13% |
| 127 | Prime Medicine Inc | PRME | 0.12% |
| 128 | Allogene Therapeutics Inc | ALLO | 0.12% |
| 129 | Ironwood Pharmaceuticals Inc | IRWD | 0.12% |
| 130 | CytomX Therapeutics Inc | CTMX | 0.12% |
| 131 | Myriad Genetics Inc | MYGN | 0.12% |
| 132 | Arbutus Biopharma Corp | ABUS | 0.12% |
| 133 | Emergent BioSolutions Inc | EBS | 0.12% |
| 134 | Climb Bio Inc | CLYM | 0.12% |
| 135 | Altimmune Inc | ALT | 0.11% |
| 136 | Editas Medicine Inc | EDIT | 0.11% |
| 137 | Solid Biosciences Inc | SLDB | 0.11% |
| 138 | Sagimet Biosciences Inc | SGMT | 0.10% |
| 139 | Shattuck Labs Inc | STTK | 0.10% |
| 140 | Monopar Therapeutics Inc | MNPR | 0.10% |
| 141 | Ocugen Inc | OCGN | 0.10% |
| 142 | Design Therapeutics Inc | DSGN | 0.10% |
| 143 | ARS Pharmaceuticals Inc | SPRY | 0.09% |
| 144 | Aktis Oncology Inc | AKTS | 0.09% |
| 145 | MiMedx Group Inc | MDXG | 0.09% |
| 146 | Cabaletta Bio Inc | CABA | 0.09% |
| 147 | Vanda Pharmaceuticals Inc | VNDA | 0.08% |
| 148 | Prothena Corp PLC | PRTA | 0.08% |
| 149 | Metsera Inc | 0.07% | |
| 150 | Assembly Biosciences Inc | ASMB | 0.06% |
| 151 | Ovid therapeutics Inc | OVID | 0.06% |
| 152 | Aura Biosciences Inc | AURA | 0.06% |
| 153 | Neurogene Inc | NGNE | 0.06% |
| 154 | Faeth Therapeutics Inc | FTH | 0.05% |
| 155 | Lexeo Therapeutics Inc | LXEO | 0.04% |
| 156 | Crescent Biopharma Inc | CBIO | 0.04% |
| 157 | Compass Therapeutics Inc | CMPX | 0.04% |
| 158 | BridgeBio Oncology Therapeutics Inc | BBOT | 0.02% |
| 159 | Contra Akero Therapeut | 0.01% | |
| 160 | Contra Inhibrx Inc | 0.01% | |
| 161 | Bristol-Myers Squibb Co | 0.01% | |
| 162 | Contra Verve Therapeut | 0.01% | |
| 163 | Contra Blueprint Medic | <0.01% | |
| 164 | OmniAb Inc | 2200963D | 0.00% |
| 165 | OmniAb Inc | 2200964D | 0.00% |
| SSI US Gov Money Market Class | 0.06% | ||
| US Dollar | -0.00% | ||
| Cash and other net assets | −0.03% |
As of Oct 13, 2026. Source: State Street.
The book
Positions165
Holdings published for (the issuer’s daily file)Oct 13, 2026
SourceState Street ↗
Top 10 together17.7%
Cash and other net assets0.02%
What this list is
How the list is built
Each weight is the share of net assets the issuer’s own daily file gives, largest first. Cash and other net assets are in their own row and are not a position. A negative weight is a short or an offsetting contract. Where a source leaves out a ticker, ETFIQ fills it from the same security in another fund’s book; names are set in title case where the source used capitals. How books are read.
Weights are as the source states them, largest first.
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Where these figures came from
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ETFIQ, Holdings of XBI, data as of Oct 13, 2026. https://etfiq.com/funds/xbi/holdings/
ETFIQ. (Oct 13, 2026). Holdings of XBI. Retrieved from https://etfiq.com/funds/xbi/holdings/
[Holdings of XBI (ETFIQ, Oct 13, 2026)](https://etfiq.com/funds/xbi/holdings/)
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