Data as of Oct 28, 2026.

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XBI vs XLB: Differences, Returns & Fees

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Over the year to Oct 28, 2026, XBI returned +41.2% to XLB's +18.5%, and XLB charges 0.08% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $10.3bn for State Street SPDR S&P Biotech ETF and $8.1bn for State Street Materials Select Sector SPDR ETF.

At a glance
+41.2%
XBI total return, 1 year
+18.5%
XLB total return, 1 year
0.35%
XBI expense ratio
0.08%
XLB expense ratio

Pair scorecard

XLB costs 0.27 points a year less; their one-year returns differ by 22.7 points; XBI is 1.3 times larger.

XBI vs XLB: Differences, Returns & Fees
MeasureXBIXLB
Return
Total return, 1 year+41.2%+18.5%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksBiotechMaterials Select Sector Index
Cost and size
Expense ratio0.35%0.08%
Net assets, as of Oct 27, 2026$10.3bn$8.1bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund18%58.5%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Feb 17, 2006 to Oct 23, 2026 · 1,079 weekly returns
XBI XLB
Return
Total return edge XBI +817.9% +412.1%
Annualized edge XBI +11.3% +8.2%
Price return edge XBI +767.9% +224.2%
Risk
Volatility edge XLB 29.2% 22.2%
Max drawdown edge XLB (slight) −61.5% −59.0%
Risk-adjusted
Sharpe edge XBI 0.45 0.39
Sortino edge XBI 0.66 0.56
Calmar edge XBI 0.18 0.14
Reading

XBI returned more: +817.9% to +412.1%. XLB swung less: 22.2% to 29.2%. XLB fell slightly less at its worst: −59.0% to −61.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: XBI vs XLB: Differences, Returns & Fees
MeasureXBIXLBEdgeHow it is measured
Return
Total return+817.9%+412.1%XBIPrice change plus distributions, reinvested.
Annualized+11.3%+8.2%XBITotal return as a yearly rate.
Price return+767.9%+224.2%XBIPrice change alone, distributions left out.
Risk
Volatility29.2%22.2%XLBSpread of weekly returns, annualized. Lower is steadier.
Downside deviation20.0%15.4%XLBLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−61.5%−59.0%XLB (slight)Deepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.450.39XBIReturn above Treasury bills per unit of volatility.
Sortino0.660.56XBIReturn above Treasury bills per unit of downside deviation.
Calmar0.180.14XBIAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,079 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, XBI and XLB hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first XBI XLB
Only in one fund ↓
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Only in XLB
LINDE PLC 12.96%
NEWMONT CORP 6.56%
FREEPORT MCMORAN INC 5.23%
ECOLAB INC 4.98%
VULCAN MATERIALS CO 4.89%
NUCOR CORP 4.89%
AIR PRODUCTS + CHEMICALS INC 4.84%
STEEL DYNAMICS INC 4.77%
Check overlap with more funds →

Side by side

XBI State Street SPDR S&P Biotech ETF XLB State Street Materials Select Sector SPDR ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Materials
Total return, 1 year +41.2% +18.5%
Expense ratio 0.35% 0.08%
Already in the S&P 500 13.2% 99.8%
Holdings 165 25
Net assets, as of Oct 27, 2026 $10.3bn $8.1bn

XBI and XLB on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-319153D2AF

XBI and XLB do different jobs. What does each one do in a portfolio?

  1. What each follows. XBI follows Biotech and XLB follows Materials Select Sector Index.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 XBI returned +41.2% and XLB +18.5% with distributions reinvested, a gap of 22.7 points.

Data as of Oct 28, 2026.

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About each fund
XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

XLB

XLB tracks an index of Materials. Over the year to Oct 28, 2026 it returned +18.5% with distributions reinvested. The prospectus expense ratio is 0.08% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 25 positions, with the top ten at 58.5%.

Questions people ask

Are XBI and XLB in the same category?
XBI is a thematic ETF and XLB is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, XBI or XLB?
In the year to Oct 28, 2026, with distributions reinvested, XBI returned +41.2% and XLB +18.5%.
Which is cheaper, XBI or XLB?
XLB is cheaper, by 0.27 percentage points a year. That is about $27 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do XBI and XLB overlap with the S&P 500?
By their latest filed holdings, 13% of XBI and 100% of XLB by weight is stocks the S&P 500 already holds.
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ETFIQ, XBI against XLB, data as of Oct 28, 2026. https://etfiq.com/compare/any/xbi-vs-xlb

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