Data as of Oct 28, 2026.

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SPYM vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, SPYM returned +13.7% to XBI's +41.2%, and SPYM charges 0.02% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $185.0bn for State Street SPDR Portfolio S&P 500 ETF and $10.3bn for State Street SPDR S&P Biotech ETF.

At a glance
+13.7%
SPYM total return, 1 year
+41.2%
XBI total return, 1 year
0.02%
SPYM expense ratio
0.35%
XBI expense ratio

Pair scorecard

SPYM costs 0.33 points a year less; their one-year returns differ by 27.5 points; SPYM is 18.0 times larger.

SPYM vs XBI: Differences, Returns & Fees
MeasureSPYMXBI
Return
Total return, 1 year+13.7%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksS&P 500 IndexBiotech
Cost and size
Expense ratio0.02%0.35%
Net assets, as of Oct 27, 2026$185.0bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common2%
Top ten holdings, share of the fund38.1%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Feb 17, 2006 to Oct 23, 2026 · 1,079 weekly returns
SPYM XBI
Return
Total return edge XBI (slight) +778.1% +817.9%
Annualized edge XBI (slight) +11.0% +11.3%
Price return edge XBI +506.0% +767.9%
Risk
Volatility edge SPYM 17.2% 29.2%
Max drawdown edge SPYM −53.9% −61.5%
Risk-adjusted
Sharpe edge SPYM 0.59 0.45
Sortino edge SPYM 0.84 0.66
Calmar edge SPYM 0.20 0.18
Reading

XBI returned slightly more: +817.9% to +778.1%. SPYM swung less: 17.2% to 29.2%. SPYM fell less at its worst: −53.9% to −61.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: SPYM vs XBI: Differences, Returns & Fees
MeasureSPYMXBIEdgeHow it is measured
Return
Total return+778.1%+817.9%XBI (slight)Price change plus distributions, reinvested.
Annualized+11.0%+11.3%XBI (slight)Total return as a yearly rate.
Price return+506.0%+767.9%XBIPrice change alone, distributions left out.
Risk
Volatility17.2%29.2%SPYMSpread of weekly returns, annualized. Lower is steadier.
Downside deviation12.2%20.0%SPYMLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−53.9%−61.5%SPYMDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.590.45SPYMReturn above Treasury bills per unit of volatility.
Sortino0.840.66SPYMReturn above Treasury bills per unit of downside deviation.
Calmar0.200.18SPYMAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,079 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

2%

By the books each fund has filed, SPYM and XBI hold 2% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

2% in common

Positions both hold · largest shared weight first SPYM XBI
ABBVIE INC 0.76% 1.67%
AMGEN INC 0.36% 1.68%
GILEAD SCIENCES INC 0.30% 1.60%
VERTEX PHARMACEUTICALS INC 0.20% 1.46%
REGENERON PHARMACEUTICALS 0.12% 1.48%
MODERNA INC 0.12% 2.24%
BIOGEN INC 0.06% 1.75%
INCYTE CORP 0.03% 1.35%
Only in one fund ↓
Only in SPYM
NVIDIA CORP 7.92%
APPLE INC 7.61%
MICROSOFT CORP 5.92%
AMAZON.COM INC 3.73%
ALPHABET INC CL A 2.83%
BROADCOM INC 2.44%
ALPHABET INC CL C 2.26%
META PLATFORMS INC CLASS A 2.05%
Only in XBI
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
SPYRE THERAPEUTICS INC 1.67%
EXELIXIS INC 1.64%
IOVANCE BIOTHERAPEUTICS INC 1.62%
ORUKA THERAPEUTICS INC 1.53%
Check overlap with more funds →

Side by side

SPYM State Street SPDR Portfolio S&P 500 ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks the S&P 500 Biotech
Total return, 1 year +13.7% +41.2%
Its benchmark over the same days +13.7% (IVV) not measured
Gap to its benchmark 0.0 pts vs IVV not measured
Expense ratio 0.02% 0.35%
Already in the S&P 500 99.8% 13.2%
Holdings 506 165
Net assets, as of Oct 27, 2026 $185.0bn $10.3bn
Former ticker SPLG none

SPYM and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-7DFC8F927B

SPYM and XBI do different jobs. What does each one do in a portfolio?

  1. What each follows. SPYM follows S&P 500 Index and XBI follows Biotech.
  2. Holdings in common. 2% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 SPYM returned +13.7% and XBI +41.2% with distributions reinvested, a gap of 27.5 points.

Data as of Oct 28, 2026.

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About each fund
SPYM

SPYM tracks the S&P 500. Over the year to Oct 28, 2026 it returned +13.7% with distributions reinvested, against +13.7% for its benchmark, the S&P 500 Index. The prospectus expense ratio is 0.02% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 506 positions, with the top ten at 38.1%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are SPYM and XBI in the same category?
SPYM is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, SPYM or XBI?
In the year to Oct 28, 2026, with distributions reinvested, SPYM returned +13.7% and XBI +41.2%.
Which is cheaper, SPYM or XBI?
SPYM is cheaper, by 0.33 percentage points a year. That is about $33 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do SPYM and XBI overlap with the S&P 500?
By their latest filed holdings, 100% of SPYM and 13% of XBI by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, SPYM against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/spym-vs-xbi

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.