Data as of Oct 28, 2026.

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MBB vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, MBB returned −0.8% to XBI's +41.2%, and MBB charges 0.04% to XBI's 0.35%.

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Net assets: $35.5bn on Oct 28, 2026 for iShares MBS ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
−0.8%
MBB total return, 1 year
+41.2%
XBI total return, 1 year
0.04%
MBB expense ratio
0.35%
XBI expense ratio

Pair scorecard

MBB costs 0.31 points a year less; their one-year returns differ by 42.0 points; MBB is 3.5 times larger.

MBB vs XBI: Differences, Returns & Fees
MeasureMBBXBI
Return
Total return, 1 year−0.8%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksBloomberg U.S. MBS IndexBiotech
Cost and size
Expense ratio0.04%0.35%
Net assets, as of Oct 26, 2026$35.6bn$10.2bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
In the S&P 500, by weight13%
Top ten holdings, share of the fund18%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Mar 23, 2007 to Oct 23, 2026 · 1,022 weekly returns
MBB XBI
Return
Total return edge XBI +63.4% +891.2%
Annualized edge XBI +2.5% +12.4%
Price return edge XBI −9.6% +837.2%
Risk
Volatility edge MBB 4.2% 29.6%
Max drawdown edge MBB −17.4% −61.5%
Risk-adjusted
Sharpe edge XBI 0.24 0.49
Sortino edge XBI 0.35 0.72
Calmar edge XBI 0.15 0.20
Reading

XBI returned more: +891.2% to +63.4%. MBB swung less: 4.2% to 29.6%. MBB fell less at its worst: −17.4% to −61.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: MBB vs XBI: Differences, Returns & Fees
MeasureMBBXBIEdgeHow it is measured
Return
Total return+63.4%+891.2%XBIPrice change plus distributions, reinvested.
Annualized+2.5%+12.4%XBITotal return as a yearly rate.
Price return−9.6%+837.2%XBIPrice change alone, distributions left out.
Risk
Volatility4.2%29.6%MBBSpread of weekly returns, annualized. Lower is steadier.
Downside deviation2.9%20.2%MBBLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−17.4%−61.5%MBBDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.240.49XBIReturn above Treasury bills per unit of volatility.
Sortino0.350.72XBIReturn above Treasury bills per unit of downside deviation.
Calmar0.150.20XBIAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,022 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, MBB and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first MBB XBI
Only in one fund ↓
Only in MBB
BLACKROCK CASH CL INST SL AGENCY 5.45%
FHLMC 30YR UMBS SUPER 1.05%
UMBS 30YR TBA(REG A) 0.60%
GNMA2 30YR 0.59%
GNMA2 30YR 0.54%
FNMA 30YR UMBS 0.53%
GNMA2 30YR 0.53%
GNMA2 30YR 0.52%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Check overlap with more funds →

Side by side

MBB iShares MBS ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Bond ETF Thematic ETF
What it is Tracks an index of mortgage-backed securities Biotech
Total return, 1 year −0.8% +41.2%
Its benchmark over the same days −1.1% (SPMB) not measured
Gap to its benchmark +0.3 pts vs SPMB not measured
Expense ratio 0.04% 0.35%
Holdings 10813 165
Net assets, MBB as of Oct 28, 2026 and XBI as of Oct 27, 2026 $35.5bn $10.3bn

MBB and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-41C4E6BCDD

MBB and XBI do different jobs. What does each one do in a portfolio?

  1. What each follows. MBB follows Bloomberg U.S. MBS Index and XBI follows Biotech.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 MBB returned −0.8% and XBI +41.2% with distributions reinvested, a gap of 42.0 points.

Data as of Oct 28, 2026.

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About each fund
MBB

MBB tracks an index of mortgage-backed securities. Over the year to Oct 28, 2026 it returned −0.8% with distributions reinvested, against −1.1% for its benchmark, the Bloomberg U.S. MBS Index. The prospectus expense ratio is 0.04% a year.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are MBB and XBI in the same category?
MBB is a bond ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, MBB or XBI?
In the year to Oct 28, 2026, with distributions reinvested, MBB returned −0.8% and XBI +41.2%.
Which is cheaper, MBB or XBI?
MBB is cheaper, by 0.31 percentage points a year. That is about $31 on $10,000 held for a year. Fees come from each fund's prospectus.
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ETFIQ, MBB against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/mbb-vs-xbi

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.