Data as of Oct 28, 2026.
XBI vs XOVR: Differences, Returns & Fees
Over the year to Oct 28, 2026, XBI returned +41.2% to XOVR's −3.0%, and XBI charges 0.35% to XOVR's 1.81%.
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Net assets: $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF, and $2.2bn on Jun 30, 2026 for ERShares Private-Public Crossover ETF.
Pair scorecard
XBI costs 1.46 points a year less; their one-year returns differ by 44.2 points.
| Measure | XBI | XOVR |
|---|---|---|
| Return | ||
| Total return, 1 year | +41.2% | −3.0% |
| Drawdown | ||
| Below its all-time high | 8.9%, high on Feb 8, 2021 | |
| Below its high | 6.5%, high on Oct 5, 2026 | |
| Benchmark | ||
| What it tracks | Biotech | No index, actively managed |
| Cost and size | ||
| Expense ratio | 0.35% | 1.81% |
| Net assets, XBI as of Oct 27, 2026 and XOVR as of Jun 30, 2026 | $10.3bn | $2.2bn |
| Active share vs the S&P 500 | 98% | |
| Holdings | ||
| Holdings in common | 3% | |
| Top ten holdings, share of the fund | 18% | 63.1% |
Holdings in common uses holdings dated Jun 30, 2026 and Oct 27, 2026. Method
What they share
By the books each fund has filed, XBI and XOVR hold 3% of their money in the same securities at the same weight. Holdings dated Jun 30, 2026 and Oct 27, 2026.
half
3% in common
Only in one fund ↓
Side by side
XBI and XOVR on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.
XBI
By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.
XOVR
XOVR is actively managed and tracks no index. Over the year to Oct 28, 2026 it returned −3.0% with distributions reinvested. The prospectus expense ratio is 1.81% a year. By its holdings filed for Jun 30, 2026, 43% of the fund by weight is stocks the S&P 500 also holds, across 32 positions, with the top ten at 63.1%. It sat 6.5% below its high of Oct 5, 2026 on Oct 28, 2026.
Questions people ask
- Are XBI and XOVR in the same category?
- XBI is a thematic ETF and XOVR is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
- Which returned more over the last year, XBI or XOVR?
- In the year to Oct 28, 2026, with distributions reinvested, XBI returned +41.2% and XOVR −3.0%.
- Which is cheaper, XBI or XOVR?
- XBI is cheaper, by 1.46 percentage points a year. That is about $146 on $10,000 held for a year. Fees come from each fund's prospectus.
Links are sources, not endorsements. A comparison is not a recommendation.
How this is computed
Overlap adds up the smaller of the two weights for each security both funds hold.
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ETFIQ, XBI against XOVR, data as of Oct 28, 2026. https://etfiq.com/compare/any/xbi-vs-xovr
ETFIQ. (Oct 28, 2026). XBI against XOVR. Retrieved from https://etfiq.com/compare/any/xbi-vs-xovr
[XBI against XOVR (ETFIQ, Oct 28, 2026)](https://etfiq.com/compare/any/xbi-vs-xovr)
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