Data as of Oct 28, 2026.

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IWF vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IWF returned +0.9% to XBI's +41.2%, and IWF charges 0.18% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $124.7bn for iShares Russell 1000 Growth ETF and $10.3bn for State Street SPDR S&P Biotech ETF.

At a glance
+0.9%
IWF total return, 1 year
+41.2%
XBI total return, 1 year
0.18%
IWF expense ratio
0.35%
XBI expense ratio

Pair scorecard

IWF costs 0.17 points a year less; their one-year returns differ by 40.3 points; IWF is 12.1 times larger.

IWF vs XBI: Differences, Returns & Fees
MeasureIWFXBI
Return
Total return, 1 year+0.9%+41.2%
Drawdown
Below its high4.8%, high on Oct 6, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksRussell 1000 Growth IndexBiotech
Cost and size
Expense ratio0.18%0.35%
Net assets, as of Oct 27, 2026$124.7bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common1%
Top ten holdings, share of the fund57.5%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IWF and XBI hold 1% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IWF XBI
AMGEN INC 0.52% 1.68%
NATERA 0.17% 1.82%
ABBVIE 0.12% 1.67%
REVOLUTION MEDICINES 0.11% 1.31%
ALNYLAM PHARMACEUTICALS 0.09% 1.29%
INSMED 0.06% 1.08%
HALOZYME THERAPEUTICS 0.04% 1.75%
NEUROCRINE BIOSCIENCES 0.04% 1.38%
BRIDGEBIO PHARMA 0.03% 1.33%
MADRIGAL PHARMACEUTICALS 0.02% 1.18%
IONIS PHARMACEUTICALS 0.02% 1.15%
ARROWHEAD PHARMACEUTICALS 0.01% 1.04%
Only in one fund ↓
Only in IWF
NVIDIA 15.30%
APPLE 8.18%
MICROSOFT 5.94%
ALPHABET CLASS A 5.62%
BROADCOM INC 4.79%
ALPHABET CLASS C 4.53%
TESLA INC 3.58%
META PLATFORMS CLASS A 3.36%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
BIOGEN INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
SPYRE THERAPEUTICS INC 1.67%
IOVANCE BIOTHERAPEUTICS INC 1.62%
GILEAD SCIENCES INC 1.60%
ORUKA THERAPEUTICS INC 1.53%
Check overlap with more funds →

Side by side

IWF iShares Russell 1000 Growth ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks the Russell 1000 growth Biotech
Total return, 1 year +0.9% +41.2%
Its benchmark over the same days +1.1% (VONG) not measured
Gap to its benchmark −0.2 pts vs VONG not measured
Expense ratio 0.18% 0.35%
Already in the S&P 500 93.5% 13.2%
Holdings 374 165
Net assets, as of Oct 27, 2026 $124.7bn $10.3bn

IWF and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IWF

IWF tracks the Russell 1000 growth. Over the year to Oct 28, 2026 it returned +0.9% with distributions reinvested, against +1.1% for its benchmark, the Russell 1000 Growth Index. The prospectus expense ratio is 0.18% a year. By its holdings published by its issuer for Oct 27, 2026, 94% of the fund by weight is stocks the S&P 500 also holds, across 374 positions, with the top ten at 57.5%. It sat 4.8% below its high of Oct 6, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are IWF and XBI in the same category?
IWF is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IWF or XBI?
In the year to Oct 28, 2026, with distributions reinvested, IWF returned +0.9% and XBI +41.2%.
Which is cheaper, IWF or XBI?
IWF is cheaper, by 0.17 percentage points a year. That is about $17 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IWF and XBI overlap with the S&P 500?
By their latest filed holdings, 94% of IWF and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, IWF against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/iwf-vs-xbi

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