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Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.

ETFIQetfiq.com · independent ETF data

IWF vs XBI: how they differ

IWF and XBI hold 0% of their weight in the same names, and XBI returned more over the year.

iShares Russell 1000 Growth ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.

What they hold in common

By the books each fund has filed, IWF and XBI hold 0% of their money in the same securities at the same weight.

Largest positions each one holds and the other does not
Only in IWFOnly in XBI
NVIDIA 15.46%MODERNA INC 2.87%
APPLE 7.77%TWIST BIOSCIENCE CORP 1.81%
ALPHABET CLASS A 5.88%HALOZYME THERAPEUTICS INC 1.47%
MICROSOFT 5.55%NATERA INC 1.46%
BROADCOM INC 5.10%KYMERA THERAPEUTICS INC 1.45%
ALPHABET CLASS C 4.77%TRAVERE THERAPEUTICS INC 1.40%
META PLATFORMS CLASS A 3.52%ROIVANT SCIENCES LTD 1.39%
MICRON TECHNOLOGY 3.35%ORUKA THERAPEUTICS INC 1.38%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026.

IWF and XBI on the fields both publish, as of Sep 13, 2026. Source: ETFIQ.
IWF
iShares Russell 1000 Growth ETF
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF
Where it sitsCore index fundCore index fund
IssueriSharesState Street
What it isRussell 1000 growthSPDR S&P Biotech
Total return, 1 year+7.0%+64.0%
S&P 500 over the same days+17.5%+17.5%
Gap to the S&P 500−10.5 pts+46.5 pts
Expense ratio0.18%0.35%
Already in the S&P 50093.6%8.5%
Holdings315154

IWF in plain words

IWF is an index equity fund tracking the Russell 1000 growth. Over the year to Sep 11, 2026 it returned +7.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.18% a year. By its holdings filed for Sep 10, 2026, 94% of the fund by weight is stocks the S&P 500 also holds, across 315 positions, with the top ten at 57.3%. It sat 5.0% below its high of Jun 1, 2026 on Sep 11, 2026.

XBI in plain words

XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.

Questions people ask

Which returned more over the last year, IWF or XBI?
In the year to Sep 13, 2026, with distributions reinvested, IWF returned +7.0% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
Which is cheaper, IWF or XBI?
IWF charges 0.18% a year and XBI charges 0.35%, so IWF is cheaper. Fees come from each fund's prospectus.
How much do IWF and XBI overlap with the S&P 500?
By their latest filed holdings, 94% of IWF and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 0% of their books are the same securities at the same weight.

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Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

IWF against XBI, ETFIQ, data as of Sep 13, 2026. Every figure is arithmetic on a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, IWF against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/iwf-vs-xbi Free to use with attribution; the underlying files are at Open data.

A comparison is not a recommendation. Standards and sources