Data as of Oct 28, 2026.

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IBB vs IWF: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to IWF's +0.9%, and IWF charges 0.18% to IBB's 0.44%.

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Net assets on Oct 27, 2026: $11.0bn for iShares Biotechnology ETF and $124.7bn for iShares Russell 1000 Growth ETF.

At a glance
+37.5%
IBB total return, 1 year
+0.9%
IWF total return, 1 year
0.44%
IBB expense ratio
0.18%
IWF expense ratio

Pair scorecard

IWF costs 0.26 points a year less; their one-year returns differ by 36.6 points; IWF is 11.3 times larger.

IBB vs IWF: Differences, Returns & Fees
MeasureIBBIWF
Return
Total return, 1 year+37.5%+0.9%
Drawdown
Below its high4.8%, high on Oct 6, 2026
Benchmark
What it tracksBiotechRussell 1000 Growth Index
Cost and size
Expense ratio0.44%0.18%
Net assets, as of Oct 27, 2026$11.0bn$124.7bn
Active share vs the S&P 50099%
Holdings
Holdings in common1%
Top ten holdings, share of the fund50%57.5%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IBB and IWF hold 1% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IBB IWF
AMGEN INC 8.20% 0.52%
NATERA 3.85% 0.17%
REVOLUTION MEDICINES 2.50% 0.11%
ALNYLAM PHARMACEUTICALS 2.11% 0.09%
INSMED 1.42% 0.06%
MEDPACE HOLDINGS 1.06% 0.05%
HALOZYME THERAPEUTICS 1.01% 0.04%
ASCENDIS PHARMA 1.06% 0.04%
NEUROCRINE BIOSCIENCES 1.02% 0.04%
BRIDGEBIO PHARMA 0.85% 0.03%
MADRIGAL PHARMACEUTICALS 0.66% 0.02%
TEMPUS AI CLASS A 0.54% 0.02%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
BIOGEN 2.58%
BEONE MEDICINES AG 2.15%
Only in IWF
NVIDIA 15.30%
APPLE 8.18%
MICROSOFT 5.94%
ALPHABET CLASS A 5.62%
BROADCOM INC 4.79%
ALPHABET CLASS C 4.53%
TESLA INC 3.58%
META PLATFORMS CLASS A 3.36%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF IWF iShares Russell 1000 Growth ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the Russell 1000 growth
Total return, 1 year +37.5% +0.9%
Its benchmark over the same days not measured +1.1% (VONG)
Gap to its benchmark not measured −0.2 pts vs VONG
Expense ratio 0.44% 0.18%
Already in the S&P 500 40.2% 93.5%
Holdings 245 374
Net assets, as of Oct 27, 2026 $11.0bn $124.7bn

IBB and IWF on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

IWF

IWF tracks the Russell 1000 growth. Over the year to Oct 28, 2026 it returned +0.9% with distributions reinvested, against +1.1% for its benchmark, the Russell 1000 Growth Index. The prospectus expense ratio is 0.18% a year. By its holdings published by its issuer for Oct 27, 2026, 94% of the fund by weight is stocks the S&P 500 also holds, across 374 positions, with the top ten at 57.5%. It sat 4.8% below its high of Oct 6, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and IWF in the same category?
IBB is a thematic ETF and IWF is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or IWF?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and IWF +0.9%.
Which is cheaper, IBB or IWF?
IWF is cheaper, by 0.26 percentage points a year. That is about $26 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and IWF overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 94% of IWF by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against IWF, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-iwf

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