Data as of Oct 28, 2026.

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IBB vs VONG: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VONG's +1.1%, and VONG charges 0.06% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $47.1bn on Sep 30, 2026 for Vanguard Russell 1000 Growth ETF.

At a glance
+37.5%
IBB total return, 1 year
+1.1%
VONG total return, 1 year
0.44%
IBB expense ratio
0.06%
VONG expense ratio

Pair scorecard

VONG costs 0.38 points a year less; their one-year returns differ by 36.4 points; VONG is 4.2 times larger.

IBB vs VONG: Differences, Returns & Fees
MeasureIBBVONG
Return
Total return, 1 year+37.5%+1.1%
Drawdown
Below its high4.8%, high on Oct 6, 2026
Benchmark
What it tracksBiotechRussell 1000 Growth Index
Cost and size
Expense ratio0.44%0.06%
Net assets, as of Sep 30, 2026$11.2bn$47.1bn
Active share vs the S&P 50099%
Holdings
Holdings in common1%
Top ten holdings, share of the fund50%57.6%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IBB and VONG hold 1% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IBB VONG
AMGEN INC 8.20% 0.47%
NATERA 3.85% 0.17%
REVOLUTION MEDICINES 2.50% 0.12%
ALNYLAM PHARMACEUTICALS 2.11% 0.10%
INSMED 1.42% 0.07%
MEDPACE HOLDINGS 1.06% 0.04%
HALOZYME THERAPEUTICS 1.01% 0.04%
NEUROCRINE BIOSCIENCES 1.02% 0.04%
ASCENDIS PHARMA 1.06% 0.03%
BRIDGEBIO PHARMA 0.85% 0.03%
MADRIGAL PHARMACEUTICALS 0.66% 0.03%
TEMPUS AI CLASS A 0.54% 0.03%
Only in one fund ↓
Only in IBB
GILEAD SCIENCES 8.56%
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
ARGENX SE ADR 3.42%
ILLUMINA INC 2.93%
BIOGEN 2.58%
BEONE MEDICINES AG 2.15%
Only in VONG
NVIDIA Corp 15.63%
Apple Inc 7.65%
Alphabet Inc 5.88%
Microsoft Corp 5.59%
Broadcom Inc 4.79%
Alphabet Inc 4.75%
Meta Platforms Inc 3.83%
Micron Technology Inc 3.52%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VONG Vanguard Russell 1000 Growth ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the Russell 1000 Growth
Total return, 1 year +37.5% +1.1%
Its benchmark over the same days not measured +0.9% (IWF)
Gap to its benchmark not measured +0.2 pts vs IWF
Expense ratio 0.44% 0.06%
Already in the S&P 500 40.2% 95.5%
Holdings 245 373
Net assets, IBB as of Oct 27, 2026 and VONG as of Sep 30, 2026 $11.0bn $47.1bn

IBB and VONG on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VONG

VONG tracks the Russell 1000 Growth. Over the year to Oct 28, 2026 it returned +1.1% with distributions reinvested, against +0.9% for its benchmark, the Russell 1000 Growth Index. The prospectus expense ratio is 0.06% a year. By its holdings published by its issuer as of Sep 30, 2026, 96% of the fund by weight is stocks the S&P 500 also holds, across 373 positions, with the top ten at 57.6%. It sat 4.8% below its high of Oct 6, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VONG in the same category?
IBB is a thematic ETF and VONG is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VONG?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VONG +1.1%.
Which is cheaper, IBB or VONG?
VONG is cheaper, by 0.38 percentage points a year. That is about $38 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VONG overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 96% of VONG by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against VONG, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-vong

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