Data as of Oct 28, 2026.

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VONG vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VONG returned +1.1% to XBI's +41.2%, and VONG charges 0.06% to XBI's 0.35%.

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Net assets: $47.1bn on Sep 30, 2026 for Vanguard Russell 1000 Growth ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+1.1%
VONG total return, 1 year
+41.2%
XBI total return, 1 year
0.06%
VONG expense ratio
0.35%
XBI expense ratio

Pair scorecard

VONG costs 0.29 points a year less; their one-year returns differ by 40.1 points; VONG is 4.5 times larger.

VONG vs XBI: Differences, Returns & Fees
MeasureVONGXBI
Return
Total return, 1 year+1.1%+41.2%
Drawdown
Below its high4.8%, high on Oct 6, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksRussell 1000 Growth IndexBiotech
Cost and size
Expense ratio0.06%0.35%
Net assets, as of Sep 30, 2026$47.1bn$10.4bn
Active share vs the S&P 50098%
Holdings
Holdings in common1%
Top ten holdings, share of the fund57.6%18%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, VONG and XBI hold 1% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first VONG XBI
Amgen Inc 0.47% 1.68%
Natera Inc 0.17% 1.82%
Revolution Medicines Inc 0.12% 1.31%
AbbVie Inc 0.11% 1.67%
Alnylam Pharmaceuticals Inc 0.10% 1.29%
Insmed Inc 0.07% 1.08%
Halozyme Therapeutics Inc 0.04% 1.75%
Neurocrine Biosciences Inc 0.04% 1.38%
Bridgebio Pharma Inc 0.03% 1.33%
Madrigal Pharmaceuticals Inc 0.03% 1.18%
Ionis Pharmaceuticals Inc 0.02% 1.15%
Arrowhead Pharmaceuticals Inc 0.02% 1.04%
Only in one fund ↓
Only in VONG
NVIDIA Corp 15.63%
Apple Inc 7.65%
Alphabet Inc 5.88%
Microsoft Corp 5.59%
Broadcom Inc 4.79%
Alphabet Inc 4.75%
Meta Platforms Inc 3.83%
Micron Technology Inc 3.52%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
BIOGEN INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
SPYRE THERAPEUTICS INC 1.67%
IOVANCE BIOTHERAPEUTICS INC 1.62%
GILEAD SCIENCES INC 1.60%
ORUKA THERAPEUTICS INC 1.53%
Check overlap with more funds →

Side by side

VONG Vanguard Russell 1000 Growth ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks the Russell 1000 Growth Biotech
Total return, 1 year +1.1% +41.2%
Its benchmark over the same days +0.9% (IWF) not measured
Gap to its benchmark +0.2 pts vs IWF not measured
Expense ratio 0.06% 0.35%
Already in the S&P 500 95.5% 13.2%
Holdings 373 165
Net assets, VONG as of Sep 30, 2026 and XBI as of Oct 27, 2026 $47.1bn $10.3bn

VONG and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
VONG

VONG tracks the Russell 1000 Growth. Over the year to Oct 28, 2026 it returned +1.1% with distributions reinvested, against +0.9% for its benchmark, the Russell 1000 Growth Index. The prospectus expense ratio is 0.06% a year. By its holdings published by its issuer as of Sep 30, 2026, 96% of the fund by weight is stocks the S&P 500 also holds, across 373 positions, with the top ten at 57.6%. It sat 4.8% below its high of Oct 6, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are VONG and XBI in the same category?
VONG is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, VONG or XBI?
In the year to Oct 28, 2026, with distributions reinvested, VONG returned +1.1% and XBI +41.2%.
Which is cheaper, VONG or XBI?
VONG is cheaper, by 0.29 percentage points a year. That is about $29 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VONG and XBI overlap with the S&P 500?
By their latest filed holdings, 96% of VONG and 13% of XBI by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, VONG against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/vong-vs-xbi

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