Data as of Oct 28, 2026.

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Across categories

IBB vs VOOG: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to VOOG's +12.1%, and VOOG charges 0.05% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $27.8bn on Sep 30, 2026 for Vanguard S&P 500 Growth ETF.

At a glance
+37.5%
IBB total return, 1 year
+12.1%
VOOG total return, 1 year
0.44%
IBB expense ratio
0.05%
VOOG expense ratio

Pair scorecard

VOOG costs 0.39 points a year less; their one-year returns differ by 25.4 points; VOOG is 2.5 times larger.

IBB vs VOOG: Differences, Returns & Fees
MeasureIBBVOOG
Return
Total return, 1 year+37.5%+12.1%
Drawdown
Below its high4.1%, high on Oct 6, 2026
Benchmark
What it tracksBiotechS&P 500 Growth Index
Cost and size
Expense ratio0.44%0.05%
Net assets, as of Sep 30, 2026$11.2bn$27.8bn
Active share vs the S&P 50099%
Holdings
Holdings in common1%
Top ten holdings, share of the fund50%60.2%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

1%

By the books each fund has filed, IBB and VOOG hold 1% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

1% in common

Positions both hold · largest shared weight first IBB VOOG
AMGEN INC 8.20% 0.42%
GILEAD SCIENCES 8.56% 0.27%
ILLUMINA INC 2.93% 0.06%
INCYTE CORP 1.63% 0.06%
Only in one fund ↓
Only in IBB
VERTEX PHARMACEUTICALS 7.53%
REGENERON PHARMACEUTICALS 5.64%
MODERNA 5.29%
NATERA 3.85%
ARGENX SE ADR 3.42%
BIOGEN 2.58%
REVOLUTION MEDICINES 2.50%
BEONE MEDICINES AG 2.15%
Only in VOOG
NVIDIA Corp 15.01%
Microsoft Corp 10.34%
Apple Inc 6.60%
Alphabet Inc 5.48%
Broadcom Inc 4.54%
Alphabet Inc 4.39%
Meta Platforms Inc 4.34%
Amazon.com Inc 3.52%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF VOOG Vanguard S&P 500 Growth ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the S&P 500 Growth
Total return, 1 year +37.5% +12.1%
Its benchmark over the same days not measured +12.1% (IVW)
Gap to its benchmark not measured 0.0 pts vs IVW
Expense ratio 0.44% 0.05%
Already in the S&P 500 40.2% 99.8%
Holdings 245 154
Net assets, IBB as of Oct 27, 2026 and VOOG as of Sep 30, 2026 $11.0bn $27.8bn

IBB and VOOG on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

VOOG

VOOG tracks the S&P 500 Growth. Over the year to Oct 28, 2026 it returned +12.1% with distributions reinvested, against +12.1% for its benchmark, the S&P 500 Growth Index. The prospectus expense ratio is 0.05% a year. By its holdings published by its issuer as of Sep 30, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 60.2%. It sat 4.1% below its high of Oct 6, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and VOOG in the same category?
IBB is a thematic ETF and VOOG is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or VOOG?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and VOOG +12.1%.
Which is cheaper, IBB or VOOG?
VOOG is cheaper, by 0.39 percentage points a year. That is about $39 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and VOOG overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 100% of VOOG by weight is stocks the S&P 500 already holds.
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ETFIQ, IBB against VOOG, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-voog

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