Data as of Oct 28, 2026.

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IBB vs ONEQ: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IBB returned +37.5% to ONEQ's +12.7%, and ONEQ charges 0.21% to IBB's 0.44%.

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Net assets: $11.0bn on Oct 27, 2026 for iShares Biotechnology ETF, and $10.9bn on Sep 30, 2026 for Fidelity Nasdaq Composite Index ETF.

At a glance
+37.5%
IBB total return, 1 year
+12.7%
ONEQ total return, 1 year
0.44%
IBB expense ratio
0.21%
ONEQ expense ratio

Pair scorecard

ONEQ costs 0.23 points a year less; their one-year returns differ by 24.8 points.

IBB vs ONEQ: Differences, Returns & Fees
MeasureIBBONEQ
Return
Total return, 1 year+37.5%+12.7%
Drawdown
Below its high3.8%, high on Oct 6, 2026
Benchmark
What it tracksBiotechNasdaq Composite Index
Cost and size
Expense ratio0.44%0.21%
Net assets, as of Sep 30, 2026$11.2bn$10.9bn
Active share vs the S&P 50099%
Holdings
Holdings in common3%
Top ten holdings, share of the fund50%56.0%

Holdings in common uses holdings dated Aug 31, 2026 and Oct 27, 2026. Method

What they share

3%

By the books each fund has filed, IBB and ONEQ hold 3% of their money in the same securities at the same weight. Holdings dated Aug 31, 2026 and Oct 27, 2026.

0 half 100%

half

3% in common

Positions both hold · largest shared weight first IBB ONEQ
AMGEN INC 8.20% 0.50%
GILEAD SCIENCES 8.56% 0.39%
VERTEX PHARMACEUTICALS 7.53% 0.30%
REGENERON PHARMACEUTICALS 5.64% 0.18%
MODERNA 5.29% 0.13%
NATERA 3.85% 0.10%
REVOLUTION MEDICINES 2.50% 0.09%
ILLUMINA INC 2.93% 0.07%
BIOGEN 2.58% 0.07%
ALNYLAM PHARMACEUTICALS 2.11% 0.07%
ARGENX SE ADR 3.42% 0.06%
INSMED 1.42% 0.06%
Only in one fund ↓
Only in IBB
GENMAB SPONSORED ADR 1.72%
UNITED THERAPEUTICS 1.71%
CHARLES RIVER LABORATORIES INTERNA 1.18%
ASCENDIS PHARMA 1.06%
MEDPACE HOLDINGS 1.06%
ABIVAX AMERICAN DEPOSITARY SHARES 0.44%
LEGEND BIOTECH ADR REP 0.25%
CAREDX 0.23%
Only in ONEQ
NVIDIA CORP 11.57%
APPLE INC 10.08%
MICROSOFT CORP 8.16%
AMAZON.COM INC 6.05%
ALPHABET INC 4.28%
ALPHABET INC 3.96%
BROADCOM INC 3.80%
TESLA INC 2.99%
Check overlap with more funds →

Side by side

IBB iShares Biotechnology ETF ONEQ Fidelity Nasdaq Composite Index ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks the Nasdaq Composite
Total return, 1 year +37.5% +12.7%
Expense ratio 0.44% 0.21%
Already in the S&P 500 40.2% 84.6%
Holdings 245 1026
Net assets, IBB as of Oct 27, 2026 and ONEQ as of Sep 30, 2026 $11.0bn $10.9bn

IBB and ONEQ on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IBB

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +37.5% with distributions reinvested.

ONEQ

ONEQ tracks the Nasdaq Composite. Over the year to Oct 28, 2026 it returned +12.7% with distributions reinvested. The prospectus expense ratio is 0.21% a year. By its holdings filed for Aug 31, 2026, 85% of the fund by weight is stocks the S&P 500 also holds, across 1,026 positions, with the top ten at 56.0%. It sat 3.8% below its high of Oct 6, 2026 on Oct 28, 2026.

Questions people ask

Are IBB and ONEQ in the same category?
IBB is a thematic ETF and ONEQ is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IBB or ONEQ?
In the year to Oct 28, 2026, with distributions reinvested, IBB returned +37.5% and ONEQ +12.7%.
Which is cheaper, IBB or ONEQ?
ONEQ is cheaper, by 0.23 percentage points a year. That is about $23 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IBB and ONEQ overlap with the S&P 500?
By their latest filed holdings, 40% of IBB and 85% of ONEQ by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, IBB against ONEQ, data as of Oct 28, 2026. https://etfiq.com/compare/any/ibb-vs-oneq

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.