Data as of Oct 28, 2026.

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VDE vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VDE returned +58.8% to XBI's +41.2%, and VDE charges 0.09% to XBI's 0.35%.

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Net assets: $10.4bn on Sep 30, 2026 for Vanguard Energy ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+58.8%
VDE total return, 1 year
+41.2%
XBI total return, 1 year
0.09%
VDE expense ratio
0.35%
XBI expense ratio

Pair scorecard

VDE costs 0.26 points a year less; their one-year returns differ by 17.6 points.

VDE vs XBI: Differences, Returns & Fees
MeasureVDEXBI
Return
Total return, 1 year+58.8%+41.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksMSCI US Investable Market Index (IMI)/Energy 25/50Biotech
Cost and size
Expense ratio0.09%0.35%
Net assets, as of Sep 30, 2026$10.4bn$10.4bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund67.1%18%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, VDE and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first VDE XBI
Only in one fund ↓
Only in VDE
ExxonMobil Holdings Corp 22.88%
Chevron Corp 14.42%
ConocoPhillips 5.87%
Marathon Petroleum Corp 4.46%
Valero Energy Corp 4.45%
Phillips 66 3.94%
Williams Cos Inc 3.16%
EOG Resources Inc 2.85%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
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Side by side

VDE Vanguard Energy ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of Energy Biotech
Total return, 1 year +58.8% +41.2%
Its benchmark over the same days +59.0% (FENY) not measured
Gap to its benchmark −0.2 pts vs FENY not measured
Expense ratio 0.09% 0.35%
Already in the S&P 500 81.2% 13.2%
Holdings 113 165
Net assets, VDE as of Sep 30, 2026 and XBI as of Oct 27, 2026 $10.4bn $10.3bn

VDE and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
VDE

VDE tracks an index of Energy. Over the year to Oct 28, 2026 it returned +58.8% with distributions reinvested, against +59.0% for its benchmark, the MSCI US Investable Market Index (IMI)/Energy 25/50. The prospectus expense ratio is 0.09% a year. By its holdings published by its issuer as of Sep 30, 2026, 81% of the fund by weight is stocks the S&P 500 also holds, across 113 positions, with the top ten at 67.1%.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are VDE and XBI in the same category?
VDE is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, VDE or XBI?
In the year to Oct 28, 2026, with distributions reinvested, VDE returned +58.8% and XBI +41.2%.
Which is cheaper, VDE or XBI?
VDE is cheaper, by 0.26 percentage points a year. That is about $26 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VDE and XBI overlap with the S&P 500?
By their latest filed holdings, 81% of VDE and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, VDE against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/vde-vs-xbi

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