Data as of Oct 28, 2026.

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Across categories

VWO vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VWO returned +4.8% to XBI's +41.2%, and VWO charges 0.06% to XBI's 0.35%.

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Net assets: $125.4bn on Sep 30, 2026 for Vanguard FTSE Emerging Markets ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+4.8%
VWO total return, 1 year
+41.2%
XBI total return, 1 year
0.06%
VWO expense ratio
0.35%
XBI expense ratio

Pair scorecard

VWO costs 0.29 points a year less; their one-year returns differ by 36.4 points; VWO is 12.1 times larger.

VWO vs XBI: Differences, Returns & Fees
MeasureVWOXBI
Return
Total return, 1 year+4.8%+41.2%
Drawdown
Below its high7.0%, high on Sep 4, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksFTSE Emerging Markets All Cap China A Inclusion IndexBiotech
Cost and size
Expense ratio0.06%0.35%
Net assets, as of Sep 30, 2026$125.4bn$10.4bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund29.8%18%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, VWO and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first VWO XBI
Only in one fund ↓
Only in VWO
Taiwan Semiconductor Manufacturing Co Ltd 15.76%
SLCMT1142 2.96%
Tencent Holdings Ltd 2.82%
Alibaba Group Holding Ltd 2.11%
MediaTek Inc 1.88%
MKTLIQ 0.95%
Delta Electronics Inc 0.95%
China Construction Bank Corp 0.91%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
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Side by side

VWO Vanguard FTSE Emerging Markets ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of Emerging markets Biotech
Total return, 1 year +4.8% +41.2%
Expense ratio 0.06% 0.35%
Already in the S&P 500 0.0% 13.2%
Holdings 6515 165
Net assets, VWO as of Sep 30, 2026 and XBI as of Oct 27, 2026 $125.4bn $10.3bn

VWO and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
VWO

VWO tracks an index of Emerging markets. Over the year to Oct 28, 2026 it returned +4.8% with distributions reinvested. The prospectus expense ratio is 0.06% a year. By its holdings published by its issuer as of Sep 30, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 6,515 positions, with the top ten at 29.8%. It sat 7.0% below its high of Sep 4, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are VWO and XBI in the same category?
VWO is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, VWO or XBI?
In the year to Oct 28, 2026, with distributions reinvested, VWO returned +4.8% and XBI +41.2%.
Which is cheaper, VWO or XBI?
VWO is cheaper, by 0.29 percentage points a year. That is about $29 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VWO and XBI overlap with the S&P 500?
By their latest filed holdings, 0% of VWO and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, VWO against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/vwo-vs-xbi

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