Data as of Oct 28, 2026.

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IYR vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, IYR returned +3.4% to XBI's +41.2%, and XBI charges 0.35% to IYR's 0.37%.

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Net assets: $3.9bn on Oct 28, 2026 for iShares U.S. Real Estate ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+3.4%
IYR total return, 1 year
+41.2%
XBI total return, 1 year
0.37%
IYR expense ratio
0.35%
XBI expense ratio

Pair scorecard

XBI costs 0.02 points a year less; their one-year returns differ by 37.8 points; XBI is 2.6 times larger.

IYR vs XBI: Differences, Returns & Fees
MeasureIYRXBI
Return
Total return, 1 year+3.4%+41.2%
Drawdown
Below its high8.6%, high on Jul 28, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksDow Jones U.S. Real Estate Capped IndexBiotech
Cost and size
Expense ratio0.37%0.35%
Net assets, as of Oct 26, 2026$4.0bn$10.2bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund52.5%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, IYR and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first IYR XBI
Only in one fund ↓
Only in IYR
WELLTOWER 9.85%
PROLOGIS REIT 8.77%
AMERICAN TOWER REIT 4.96%
SIMON PROPERTY GROUP REIT INC 4.71%
EQUINIX REIT 4.57%
DIGITAL REALTY TRUST REIT 4.54%
REALTY INCOME REIT 4.19%
PUBLIC STORAGE REIT 4.10%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Check overlap with more funds →

Side by side

IYR iShares U.S. Real Estate ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of U.S. Real Estate Biotech
Total return, 1 year +3.4% +41.2%
Expense ratio 0.37% 0.35%
Already in the S&P 500 80.0% 13.2%
Holdings 59 165
Net assets, IYR as of Oct 28, 2026 and XBI as of Oct 27, 2026 $3.9bn $10.3bn

IYR and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
IYR

IYR tracks an index of U.S. Real Estate. Over the year to Oct 28, 2026 it returned +3.4% with distributions reinvested. The prospectus expense ratio is 0.37% a year. By its holdings published by its issuer for Oct 27, 2026, 80% of the fund by weight is stocks the S&P 500 also holds, across 59 positions, with the top ten at 52.5%. It sat 8.6% below its high of Jul 28, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are IYR and XBI in the same category?
IYR is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, IYR or XBI?
In the year to Oct 28, 2026, with distributions reinvested, IYR returned +3.4% and XBI +41.2%.
Which is cheaper, IYR or XBI?
XBI is cheaper, by 0.02 percentage points a year. That is about $2 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do IYR and XBI overlap with the S&P 500?
By their latest filed holdings, 80% of IYR and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, IYR against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/iyr-vs-xbi

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