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AIQ vs XBI: which is really different?

AIQ and XBI hold 0% of their weight in the same names, and XBI returned +45.0% over the year. Global X Artificial Intelligence & Technology ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.

XBI costs 0.33 points a year less; their one-year returns differ by 15.0 points.

AIQXBI
Expense ratio0.68%0.35%
Net assets, AIQ as of Oct 9, 2026 and XBI as of Oct 8, 2026$10.7bn$9.9bn
Total return, 1 year+30.0%+45.0%
What it tracksArtificial intelligenceBiotech
Holdings in common0%
S&P 500, total return, 1 year+17.3%
Against the S&P 500, 1 yearahead by 12.8 ptsahead by 27.7 pts
Below its all-time high5.0%, high on Jun 2, 202611.1%, high on Feb 8, 2021

Holdings in common uses holdings dated Oct 8, 2026 and Oct 9, 2026.

55.6%
AIQ in the S&P 500
12.7%
XBI in the S&P 500
+30.0%
AIQ total return, 1 year
+45.0%
XBI total return, 1 year
AIQ · 1 year to Oct 9, 202644% of its weight is outside the S&P 500
44% of its weight is outside the S&P 50056% of AIQ's weight is in S&P 500 companies and 44% is outside the index. Holdings as of Oct 9, 2026.56%44%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 70% · top ten 33% of the fund · 88 holdings as published by its issuer for Oct 9, 2026 · Nasdaq-100: 48% in44% of its weight is outside the S&P 50056% of AIQ's weight is in S&P 500 companies and 44% is outside the index. Holdings as of Oct 9, 2026.56%44%in the S&P 500outsideactive share 70% · Nasdaq-100: 48% in

56% of AIQ's weight is in S&P 500 companies and 44% is outside the index. Holdings as of Oct 9, 2026.

XBI · 1 year to Oct 9, 202687% of its weight is outside the S&P 500
87% of its weight is outside the S&P 50013% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 8, 2026.13%87%inof its weight outside the S&P 500active share 98% · top ten 17% of the fund · 165 holdings as published by its issuer for Oct 8, 2026 · Nasdaq-100: 9% in87% of its weight is outside the S&P 50013% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 8, 2026.13%87%inof its weight outside the S&P 500active share 98% · Nasdaq-100: 9% in

13% of XBI's weight is in S&P 500 companies and 87% is outside the index. Holdings as of Oct 8, 2026.

ETFIQ Off-Index Score · XBI scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.3, the highest

A percentile among the 391 thematic ETFs with a holdings filing. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, AIQ and XBI hold 0% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Oct 8, 2026 and Oct 9, 2026.

half

0% in common

Positions both hold, largest shared weight first
Holding AIQ XBI
Only in AIQ
PALANTIR TECHNOLOGIES INC-A 4.46%
MICROSOFT CORP 3.69%
SPACE EXPLORATION TECHN-CL A 3.62%
TESLA INC 3.15%
META PLATFORMS INC 3.12%
ORACLE CORP 3.10%
ADVANCED MICRO DEVICES 2.97%
AMAZON.COM INC 2.96%
Only in XBI
MODERNA INC 2.20%
TWIST BIOSCIENCE CORP 1.84%
NATERA INC 1.79%
ABBVIE INC 1.65%
UNITED THERAPEUTICS CORP 1.59%
AMGEN INC 1.58%
BIOGEN INC 1.57%
HALOZYME THERAPEUTICS INC 1.55%

0% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowAIQXBIAIQXBIAIQXBI
3 months+5.0%−3.3%+1.6 pts−6.7 pts+1.3 pts−7.0 pts
6 months+34.9%+18.9%+19.7 pts+3.8 pts+11.7 pts−4.3 pts
1 year+30.0%+45.0%+12.8 pts+27.7 pts+6.4 pts+21.4 pts
3 years+142.2%+114.6%+56.4 pts+28.8 pts+34.9 pts+7.3 pts
Since launch
AIQ May 2018 · XBI Feb 2006
+355.8%+890.7%+130.3 pts+92.2 pts−14.1 pts−1,164.7 pts

Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

AIQ
Global X Artificial Intelligence & Technology ETF · Holds 88 stocks in artificial intelligence, 56% of its weight in S&P 500 companies
XBI
State Street(R) SPDR(R) S&P(R) Biotech ETF · Holds 165 stocks in biotech, 13% of its weight in S&P 500 companies
Issuer Global X State Street
Theme Artificial intelligence Biotech
In the S&P 500 55.6% 12.7%
Active share vs the S&P 500 69.9% 98.4%
In the Nasdaq-100 48.0% 8.5%
Holdings 88 165
Top ten, share of the fund 32.9% 16.9%
Expense ratio 0.68% 0.35%
Fee for the differing part 0.97% 0.36%
Total return, 1 year +30.0% +45.0%
vs the S&P 500 +12.8 pts +27.7 pts
vs the Nasdaq-100 +6.4 pts +21.4 pts
Below its high −5.0% −11.1%
Net assets, AIQ as of Oct 9, 2026 and XBI as of Oct 8, 2026 $10.7bn $9.9bn

As of Oct 9, 2026. Source: ETFIQ.

AIQ in plain words

By weight, 56% of AIQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 70%. The top ten holdings are 33% of the fund across 88 positions, as published by its issuer for Oct 9, 2026. Over the year to Oct 9, 2026 the fund returned +30.0% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 12.8 pts. It sits 5.0% below its all-time high of Jun 2, 2026.

XBI in plain words

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 17% of the fund across 165 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +45.0% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 27.7 pts. It sits 11.1% below its all-time high of Feb 8, 2021.

Questions people ask

Do AIQ and XBI hold the same stocks?
By their latest filings, 0% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, AIQ or XBI?
AIQ has 56% of its weight in S&P 500 names and XBI has 13%, so XBI differs more from the index.
Which is cheaper, AIQ or XBI?
AIQ charges 0.68% a year and XBI charges 0.35%, so XBI is cheaper. Fees come from each fund's prospectus.
Other comparisons
AIQ vs IBBAIQ vs AIRRAIQ vs GDXJAIQ vs GRIDXBI vs BAIXBI vs ARTYXBI vs SILXBI vs XME
AIQ on its own →XBI on its own →How every figure is computed →Standards and sources →
Where these figures came from
AIQ filings on SEC EDGAR ↗AIQ prospectus with the expense ratio (SEC) ↗Global X page for AIQ ↗XBI filings on SEC EDGAR ↗XBI prospectus with the expense ratio (SEC) ↗State Street website ↗

ETFIQ links to the documents behind every figure; a link is not an endorsement. A comparison is not a recommendation.

How this is computed

It is a position in a set, not a rating, and neither end of it is a recommendation.

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

Every figure is an ETFIQ calculation with distributions reinvested.

Cite this page

ETFIQ, AIQ against XBI, data as of Oct 9, 2026. https://etfiq.com/compare/themes/aiq-vs-xbi

Open data

Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms.