Data as of Oct 28, 2026.

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XBI vs XLI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, XBI returned +41.2% to XLI's +10.2%, and XLI charges 0.08% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $10.3bn for State Street SPDR S&P Biotech ETF and $30.8bn for State Street Industrial Select Sector SPDR ETF.

At a glance
+41.2%
XBI total return, 1 year
+10.2%
XLI total return, 1 year
0.35%
XBI expense ratio
0.08%
XLI expense ratio

Pair scorecard

XLI costs 0.27 points a year less; their one-year returns differ by 31.0 points; XLI is 3.0 times larger.

XBI vs XLI: Differences, Returns & Fees
MeasureXBIXLI
Return
Total return, 1 year+41.2%+10.2%
Drawdown
Below its all-time high8.9%, high on Feb 8, 2021
Below its high9.4%, high on Aug 14, 2026
Benchmark
What it tracksBiotechIndustrial Select Sector Index
Cost and size
Expense ratio0.35%0.08%
Net assets, as of Oct 27, 2026$10.3bn$30.8bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund18%37.8%

Holdings in common uses holdings dated Oct 27, 2026. Method

Risk and return

Feb 17, 2006 to Oct 23, 2026 · 1,079 weekly returns
XBI XLI
Return
Total return edge XBI +817.9% +652.9%
Annualized edge XBI (slight) +11.3% +10.2%
Price return edge XBI +767.9% +405.9%
Risk
Volatility edge XLI 29.2% 20.8%
Max drawdown edge Tie −61.5% −61.6%
Risk-adjusted
Sharpe edge XLI (slight) 0.45 0.49
Sortino edge XLI (slight) 0.66 0.70
Calmar edge XBI (slight) 0.18 0.17
Reading

XBI returned more: +817.9% to +652.9%. XLI swung less: 20.8% to 29.2%. XBI and XLI fell about the same at their worst: −61.5% and −61.6%.

Full scorecard

9 measures, with how each is measured
Open ↓
Risk and return: XBI vs XLI: Differences, Returns & Fees
MeasureXBIXLIEdgeHow it is measured
Return
Total return+817.9%+652.9%XBIPrice change plus distributions, reinvested.
Annualized+11.3%+10.2%XBI (slight)Total return as a yearly rate.
Price return+767.9%+405.9%XBIPrice change alone, distributions left out.
Risk
Volatility29.2%20.8%XLISpread of weekly returns, annualized. Lower is steadier.
Downside deviation20.0%14.4%XLILike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−61.5%−61.6%TieDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.450.49XLI (slight)Return above Treasury bills per unit of volatility.
Sortino0.660.70XLI (slight)Return above Treasury bills per unit of downside deviation.
Calmar0.180.17XBI (slight)Annualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,079 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

0%

By the books each fund has filed, XBI and XLI hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first XBI XLI
Only in one fund ↓
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Only in XLI
CATERPILLAR INC 6.14%
GENERAL ELECTRIC 5.79%
RTX CORP 4.91%
GE VERNOVA INC 4.47%
UNION PACIFIC CORP 3.34%
DEERE + CO 3.01%
EATON CORP PLC 2.79%
UBER TECHNOLOGIES INC 2.52%
Check overlap with more funds →

Side by side

XBI State Street SPDR S&P Biotech ETF XLI State Street Industrial Select Sector SPDR ETF
Where it sits Thematic ETF Stock ETF
What it is Biotech Tracks an index of Industrials
Total return, 1 year +41.2% +10.2%
Its benchmark over the same days not measured +13.6% (SPY)
Gap to its benchmark not measured −3.4 pts vs SPY
Expense ratio 0.35% 0.08%
Already in the S&P 500 13.2% 99.9%
Holdings 165 84
Net assets, as of Oct 27, 2026 $10.3bn $30.8bn

XBI and XLI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-1266D251CF

XBI and XLI do different jobs. What does each one do in a portfolio?

  1. What each follows. XBI follows Biotech and XLI follows Industrial Select Sector Index.
  2. Holdings in common. 0% of the weight is in the same securities (holdings dated Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 XBI returned +41.2% and XLI +10.2% with distributions reinvested, a gap of 31.0 points.

Data as of Oct 28, 2026.

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About each fund
XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

XLI

XLI tracks an index of Industrials. Over the year to Oct 28, 2026 it returned +10.2% with distributions reinvested, against +13.6% for its benchmark, the S&P 500 Index. The prospectus expense ratio is 0.08% a year. By its holdings published by its issuer for Oct 27, 2026, 100% of the fund by weight is stocks the S&P 500 also holds, across 84 positions, with the top ten at 37.8%. It sat 9.4% below its high of Aug 14, 2026 on Oct 28, 2026.

Questions people ask

Are XBI and XLI in the same category?
XBI is a thematic ETF and XLI is a stock ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, XBI or XLI?
In the year to Oct 28, 2026, with distributions reinvested, XBI returned +41.2% and XLI +10.2%.
Which is cheaper, XBI or XLI?
XLI is cheaper, by 0.27 percentage points a year. That is about $27 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do XBI and XLI overlap with the S&P 500?
By their latest filed holdings, 13% of XBI and 100% of XLI by weight is stocks the S&P 500 already holds.
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ETFIQ, XBI against XLI, data as of Oct 28, 2026. https://etfiq.com/compare/any/xbi-vs-xli

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