Data as of Oct 28, 2026.

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Across categories

EFA vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, EFA returned +12.1% to XBI's +41.2%, and EFA charges 0.32% to XBI's 0.35%.

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Net assets on Oct 27, 2026: $76.8bn for iShares MSCI EAFE ETF and $10.3bn for State Street SPDR S&P Biotech ETF.

At a glance
+12.1%
EFA total return, 1 year
+41.2%
XBI total return, 1 year
0.32%
EFA expense ratio
0.35%
XBI expense ratio

Pair scorecard

EFA costs 0.03 points a year less; their one-year returns differ by 29.1 points; EFA is 7.5 times larger.

EFA vs XBI: Differences, Returns & Fees
MeasureEFAXBI
Return
Total return, 1 year+12.1%+41.2%
Drawdown
Below its high4.7%, high on Aug 25, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksMSCI EAFE IndexBiotech
Cost and size
Expense ratio0.32%0.35%
Net assets, as of Oct 27, 2026$76.8bn$10.3bn
Active share vs the S&P 50098%
Holdings
Holdings in common0%
Top ten holdings, share of the fund14.3%18%

Holdings in common uses holdings dated Oct 27, 2026. Method

What they share

0%

By the books each fund has filed, EFA and XBI hold 0% of their money in the same securities at the same weight. Holdings dated Oct 27, 2026.

0 half 100%

half

0% in common

Positions both hold · largest shared weight first EFA XBI
ERSTE GROUP BANK AG 0.17% 0.11%
Only in one fund ↓
Only in EFA
ASML HOLDING 2.98%
ROCHE PS PAR AG 1.58%
SHELL 1.42%
HSBC HOLDINGS PLC 1.38%
NOVARTIS AG 1.33%
ASTRAZENECA PLC 1.21%
NESTLE SA 1.21%
SAP 1.13%
Only in XBI
MODERNA INC 2.24%
TWIST BIOSCIENCE CORP 1.86%
NATERA INC 1.82%
BIOGEN INC 1.75%
HALOZYME THERAPEUTICS INC 1.75%
UNITED THERAPEUTICS CORP 1.71%
AMGEN INC 1.68%
ABBVIE INC 1.67%
Check overlap with more funds →

Side by side

EFA iShares MSCI EAFE ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of Developed markets ex US Biotech
Total return, 1 year +12.1% +41.2%
Its benchmark over the same days +14.3% (ACWX) not measured
Gap to its benchmark −2.2 pts vs ACWX not measured
Expense ratio 0.32% 0.35%
Already in the S&P 500 0.0% 13.2%
Holdings 665 165
Net assets, as of Oct 27, 2026 $76.8bn $10.3bn

EFA and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

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About each fund
EFA

EFA tracks an index of Developed markets ex US. Over the year to Oct 28, 2026 it returned +12.1% with distributions reinvested, against +14.3% for its benchmark, the MSCI ACWI ex USA Index. The prospectus expense ratio is 0.32% a year. By its holdings published by its issuer for Oct 27, 2026, 0% of the fund by weight is stocks the S&P 500 also holds, across 665 positions, with the top ten at 14.3%. It sat 4.7% below its high of Aug 25, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are EFA and XBI in the same category?
EFA is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, EFA or XBI?
In the year to Oct 28, 2026, with distributions reinvested, EFA returned +12.1% and XBI +41.2%.
Which is cheaper, EFA or XBI?
EFA is cheaper, by 0.03 percentage points a year. That is about $3 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do EFA and XBI overlap with the S&P 500?
By their latest filed holdings, 0% of EFA and 13% of XBI by weight is stocks the S&P 500 already holds.
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ETFIQ, EFA against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/efa-vs-xbi

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