Data as of Oct 28, 2026.

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VB vs XBI: Differences, Returns & Fees

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Over the year to Oct 28, 2026, VB returned +14.4% to XBI's +41.2%, and VB charges 0.03% to XBI's 0.35%.

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Net assets: $76.9bn on Sep 30, 2026 for Vanguard Morningstar Small-Cap ETF, and $10.3bn on Oct 27, 2026 for State Street SPDR S&P Biotech ETF.

At a glance
+14.4%
VB total return, 1 year
+41.2%
XBI total return, 1 year
0.03%
VB expense ratio
0.35%
XBI expense ratio

Pair scorecard

VB costs 0.32 points a year less; their one-year returns differ by 26.8 points; VB is 7.4 times larger.

VB vs XBI: Differences, Returns & Fees
MeasureVBXBI
Return
Total return, 1 year+14.4%+41.2%
Drawdown
Below its high5.7%, high on Aug 14, 2026
Below its all-time high8.9%, high on Feb 8, 2021
Benchmark
What it tracksMorningstar US Small Cap IndexBiotech
Cost and size
Expense ratio0.03%0.35%
Net assets, as of Sep 30, 2026$76.9bn$10.4bn
Active share vs the S&P 50098%
Holdings
Holdings in common6%
Top ten holdings, share of the fund5.9%18%

Holdings in common uses holdings dated Sep 30, 2026 and Oct 27, 2026. Method

Risk and return

Feb 17, 2006 to Oct 23, 2026 · 1,079 weekly returns
VB XBI
Return
Total return edge XBI +505.2% +817.9%
Annualized edge XBI +9.1% +11.3%
Price return edge XBI +347.2% +767.9%
Risk
Volatility edge VB 22.0% 29.2%
Max drawdown edge VB (slight) −58.8% −61.5%
Risk-adjusted
Sharpe edge XBI (slight) 0.43 0.45
Sortino edge XBI (slight) 0.60 0.66
Calmar edge XBI 0.15 0.18
Reading

XBI returned more: +817.9% to +505.2%. VB swung less: 22.0% to 29.2%. VB fell slightly less at its worst: −58.8% to −61.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: VB vs XBI: Differences, Returns & Fees
MeasureVBXBIEdgeHow it is measured
Return
Total return+505.2%+817.9%XBIPrice change plus distributions, reinvested.
Annualized+9.1%+11.3%XBITotal return as a yearly rate.
Price return+347.2%+767.9%XBIPrice change alone, distributions left out.
Risk
Volatility22.0%29.2%VBSpread of weekly returns, annualized. Lower is steadier.
Downside deviation15.5%20.0%VBLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−58.8%−61.5%VB (slight)Deepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.430.45XBI (slight)Return above Treasury bills per unit of volatility.
Sortino0.600.66XBI (slight)Return above Treasury bills per unit of downside deviation.
Calmar0.150.18XBIAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 1,079 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

6%

By the books each fund has filed, VB and XBI hold 6% of their money in the same securities at the same weight. Holdings dated Sep 30, 2026 and Oct 27, 2026.

0 half 100%

half

6% in common

Positions both hold · largest shared weight first VB XBI
Natera Inc 0.72% 1.82%
Revolution Medicines Inc 0.53% 1.31%
Moderna Inc 0.44% 2.24%
United Therapeutics Corp 0.29% 1.71%
Incyte Corp 0.27% 1.35%
Roivant Sciences Ltd 0.23% 1.28%
Neurocrine Biosciences Inc 0.18% 1.38%
Exelixis Inc 0.17% 1.64%
Twist Bioscience Corp 0.16% 1.86%
Halozyme Therapeutics Inc 0.16% 1.75%
Insmed Inc 0.16% 1.08%
BioMarin Pharmaceutical Inc 0.15% 1.26%
Only in one fund ↓
Only in VB
SLCMT1142 1.31%
Twilio Inc 0.57%
Everpure Inc 0.52%
Illumina Inc 0.52%
Okta Inc 0.44%
EMCOR Group Inc 0.42%
Credo Technology Group Holding Ltd 0.42%
Jabil Inc 0.38%
Only in XBI
BIOGEN INC 1.75%
AMGEN INC 1.68%
ABBVIE INC 1.67%
GILEAD SCIENCES INC 1.60%
REGENERON PHARMACEUTICALS 1.48%
VERTEX PHARMACEUTICALS INC 1.46%
GRAIL INC 1.46%
CRISPR THERAPEUTICS AG 1.38%
Check overlap with more funds →

Side by side

VB Vanguard Morningstar Small-Cap ETF XBI State Street SPDR S&P Biotech ETF
Where it sits Stock ETF Thematic ETF
What it is Tracks an index of Small-Cap Biotech
Total return, 1 year +14.4% +41.2%
Expense ratio 0.03% 0.35%
Already in the S&P 500 21.6% 13.2%
Holdings 1303 165
Net assets, VB as of Sep 30, 2026 and XBI as of Oct 27, 2026 $76.9bn $10.3bn

VB and XBI on the fields both publish, as of Oct 28, 2026. Source: ETFIQ.

Client brief · page 1 of 2 Report BR-E3F26CF9D2

VB and XBI do different jobs. What does each one do in a portfolio?

  1. What each follows. VB follows Morningstar US Small Cap Index and XBI follows Biotech.
  2. Holdings in common. 6% of the weight is in the same securities (holdings dated Sep 30, 2026 and Oct 27, 2026).
  3. One-year total return. Over 1 year to Oct 28, 2026 VB returned +14.4% and XBI +41.2% with distributions reinvested, a gap of 26.8 points.

Data as of Oct 28, 2026.

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About each fund
VB

VB tracks an index of Small-Cap. Over the year to Oct 28, 2026 it returned +14.4% with distributions reinvested. The prospectus expense ratio is 0.03% a year. By its holdings published by its issuer as of Sep 30, 2026, 22% of the fund by weight is stocks the S&P 500 also holds, across 1,303 positions, with the top ten at 5.9%. It sat 5.7% below its high of Aug 14, 2026 on Oct 28, 2026.

XBI

By weight, 13% of XBI's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 18% of the fund across 165 positions, as published by its issuer for Oct 27, 2026. Over the year to Oct 28, 2026 the fund returned +41.2% with distributions reinvested. It sits 8.9% below its all-time high of Feb 8, 2021.

Questions people ask

Are VB and XBI in the same category?
VB is a stock ETF and XBI is a thematic ETF, so they do different jobs. The table compares what both publish: return, cost and holdings.
Which returned more over the last year, VB or XBI?
In the year to Oct 28, 2026, with distributions reinvested, VB returned +14.4% and XBI +41.2%.
Which is cheaper, VB or XBI?
VB is cheaper, by 0.32 percentage points a year. That is about $32 on $10,000 held for a year. Fees come from each fund's prospectus.
How much do VB and XBI overlap with the S&P 500?
By their latest filed holdings, 22% of VB and 13% of XBI by weight is stocks the S&P 500 already holds.
Other comparisons
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ETFIQ, VB against XBI, data as of Oct 28, 2026. https://etfiq.com/compare/any/vb-vs-xbi

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.