BBC Virtus Biotech Clinical Trials ETF

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$43.62
+1.9% · 1 day, price
IQ’s readingComputed nightly from ETFIQ data. Not written live.

Between Jul 31, 2026 and Oct 12, 2026, BBC lost 11.7%, against −11.6% for its own holdings.

Holds 131 stocks in biotech, 0% of its weight in S&P 500 companiesVirtus ↗Expense ratio 0.65%Fund assets $46m net assets, latest filing (Jul 31, 2026)First traded Dec 17, 2014Benchmark Its own holdings, as of Jul 31, 2026; no other fund tracks the LifeSci Biotechnology Clinical Trials Index, the index its prospectus namesSEC filings ↗Every Virtus fund ETFIQ coversDividend history

Promise check: Not measuredETFIQ has not yet listed which companies belong to the biotech theme.

BBC risk and return scorecard

vs its own holdings

Not measured: its benchmark is its own holdings, which has no weekly price series.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data

Money in and out

Net fund flows · Jul 31, 2026
12 months to Jul 31, 2026
+$11.7m
3 years to Jul 31, 2026
+$15.6m
5 years to Jul 31, 2026
+$5.9m

What you earned

BBC −2.2%: total return over one month to Nov 4, 2026.
BBC−2.2%
BBC −14.8%: total return over three months to Nov 4, 2026.
BBC−14.8%
BBC −5.2%: total return over six months to Nov 4, 2026.
BBC−5.2%
BBC +13.1%: total return over the year to Nov 4, 2026.
BBC+13.1%
BBC +45.9%: total return over one year to Nov 4, 2026.
BBC+45.9%
BBC +132.0%: total return over three years to Nov 4, 2026.
BBC+132.0%
BBC −5.5%: total return over five years to Nov 4, 2026.
BBC−5.5%
BBC +165.1%: total return over ten years to Nov 4, 2026.
BBC+165.1%
BBC +72.8%: total return since launch to Nov 4, 2026.
BBC+72.8%

What did you actually buy?

Biotech · holdings as of Jul 31, 2026
0.0%
Already in the S&P 500
100.0%
Active share vs the S&P 500
11.8%
Top ten holdings
+45.9%
Total return, 1 year
2.2%
12-month yield, capital gains included, on its starting price
$0.6554
Last payment (paid annually), ex-date Dec 22, 2025
Share already in the S&P 500
0.0% of the fund by weight, holdings as of Jul 31, 2026.
Ten largest holdings
FIRST TRACKS BIOTHERAPEUTICS INC1.7%
MBX BIOSCIENCES INC1.2%
ATAIBECKLEY INC1.2%
MONOPAR THERAPEUTICS INC1.2%
DEFINIUM THERAPEUTICS INC1.2%
XENCOR INC1.1%
ZENAS BIOPHARMA INC1.1%
UNIQURE NV1.1%
APOGEE THERAPEUTICS INC1.0%
VOR BIOPHARMA INC1.0%

More on BBC

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Price, 1 year

$43.62+1.9%1 day, priceClose, Nov 4, 2026

Price only. Total return over the same days, distributions reinvested, was +45.9%. Computed by ETFIQ from Tiingo daily prices.

Source: Tiingo end-of-day prices. Data as of Nov 4, 2026. Updated every trading night. Report a data error

Points (pts) are percentage points.

BBC returns by window: total return, cash paid and price change
WindowTotal returnS&P 500 (SPY)
1M Oct 5 – Nov 4, 2026−2.2%−1.0%
3M Aug 5 – Nov 4, 2026−14.8%−0.1%
6M May 6 – Nov 4, 2026−5.2%+5.0%
YTD Dec 31, 2025 – Nov 4, 2026+13.1%+13.3%
1Y Nov 4, 2025 – Nov 4, 2026+45.9%+14.8%
3Y Nov 3, 2023 – Nov 4, 2026+132.0%+82.9%
5Y Nov 5, 2021 – Nov 4, 2026−5.5%+75.0%
10Y Nov 4, 2016 – Nov 4, 2026+165.1%+330.8%
Since launch Dec 17, 2014 – Nov 4, 2026+72.8%+364.1%
Since launch, annualised Dec 17, 2014 – Nov 4, 2026+4.7%–

Total returns, distributions reinvested.

Source: Tiingo end-of-day prices, with distributions reinvested.

Money in and out

Monthly data · as of Jul 31, 2026

BBC: in the month to Jul 31, 2026, net $161k came in, by its SEC filing.

12 months
+$11.7m
77.3% of $15.1m on Jul 31, 2025
Aug 1, 2025 to Jul 31, 2026
monthly, from SEC filings
3 years
+$15.6m
129.3% of $12.1m on Jul 31, 2023
Aug 1, 2023 to Jul 31, 2026
monthly, from SEC filings
5 years
+$5.9m
Aug 1, 2021 to Jul 31, 2026
monthly, from SEC filings
Since Aug 2019
+$1.7m
Aug 1, 2019 to Jul 31, 2026
monthly, from SEC filings

Computed by ETFIQ from the monthly sales and redemptions BBC files with the SEC on Form N-PORT.

How this is computed

ETFIQ reads no daily data for this fund, so its flows are monthly, and the latest month filed is Jul 2026. Every day and month ETFIQ holds for BBC, back to Aug 2019, is in its flows file. Flows across every fund · How these flows are computed · Compare BBC with other funds in the flows tool

Month by month, money in and money outAug 2023 to Jul 2026

BBC, money in and money out each month from Aug 2023 to Jul 2026: two bars a month, money in above the line and money out below. Every bar is from BBC’s SEC filings (N-PORT item B.6). Of the 36 months listed, money came in on net in 9 and went out in 10.

Every bar is from BBC’s SEC filings (N-PORT item B.6). Of the 36 months listed, money came in on net in 9 and went out in 10.

MonthInOutNet
Jul 2026 SEC Form N-PORT+$5.2m−$5.1m+$161k
Jun 2026 SEC Form N-PORT$0−$2.1m−$2.1m
May 2026 SEC Form N-PORT+$9.1m−$2.1m+$7.0m
Apr 2026 SEC Form N-PORT+$2.3m−$2.1m+$175k
Mar 2026 SEC Form N-PORT$0−$2.0m−$2.0m
Feb 2026 SEC Form N-PORT+$2.0m−$2.0m−$26k
Jan 2026 SEC Form N-PORT+$1.9m$0+$1.9m
Dec 2025 SEC Form N-PORT+$9.7m−$3.8m+$5.9m
Nov 2025 SEC Form N-PORT+$1.8m$0+$1.8m
Oct 2025 SEC Form N-PORT$0$0$0
Sep 2025 SEC Form N-PORT$0−$1.2m−$1.2m
Aug 2025 SEC Form N-PORT$0$0$0
Jul 2025 SEC Form N-PORT+$3.2m$0+$3.2m
Jun 2025 SEC Form N-PORT+$2.0m−$1.9m+$122k
May 2025 SEC Form N-PORT$0−$4.4m−$4.4m
Apr 2025 SEC Form N-PORT+$6.8m−$7.0m−$188k
Mar 2025 SEC Form N-PORT+$9.9m$0+$9.9m
Feb 2025 SEC Form N-PORT$0$0$0
Jan 2025 SEC Form N-PORT$0−$1.1m−$1.1m
Dec 2024 SEC Form N-PORT$0−$1.2m−$1.2m
Nov 2024 SEC Form N-PORT$0$0$0
Oct 2024 SEC Form N-PORT$0$0$0
Sep 2024 SEC Form N-PORT$0$0$0
Aug 2024 SEC Form N-PORT$0$0$0
Jul 2024 SEC Form N-PORT$0$0$0
Jun 2024 SEC Form N-PORT$0$0$0
May 2024 SEC Form N-PORT$0$0$0
Apr 2024 SEC Form N-PORT$0$0$0
Mar 2024 SEC Form N-PORT$0$0$0
Feb 2024 SEC Form N-PORT$0$0$0
Jan 2024 SEC Form N-PORT$0−$1.2m−$1.2m
Dec 2023 SEC Form N-PORT$0$0$0
Nov 2023 SEC Form N-PORT$0$0$0
Oct 2023 SEC Form N-PORT$0$0$0
Sep 2023 SEC Form N-PORT$0$0$0
Aug 2023 SEC Form N-PORT$0−$1.1m−$1.1m

Most recent first.

How this is computed

N-PORT months: money in is sales plus reinvestments; money out is redemptions.

N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.

Source: ETFIQ, from the fund’s SEC N-PORT filings. Data as of Jul 31, 2026. Updated when the fund files its next report.

BBC key stats

52-week high, daily closes to Nov 4, 2026 (ETFIQ)$56.03 on Aug 19, 2026
52-week low, daily closes to Nov 4, 2026 (ETFIQ)$29.69 on Nov 7, 2025
Close on Nov 4, 2026, within that range (ETFIQ)$43.62, 53% of the way from the low to the high
Holdings131
Top ten holdings weight11.8%
Range, beta and R-squared computed by ETFIQ from Tiingo daily prices.

Trading

as of Nov 4, 2026
Trading · BBCas of Nov 4, 2026
·
Not scored2 of 6 measured · Nov 4, 2026
0 · Hard to tradeIQ Liquidity Score100 · Trades like a giant
Cost for your order · one way, half its 30-day median spread
How to tradeSpread not read.
Full trading page: components, premium history, dealers →

BBC for holders outside the US

US tax withheld on dividends, no treaty30%
Treaty rates on dividends (IRS table, read Oct 30, 2026)65 countries, 10% to 30%
BBC interest-related and short-term gain dividendsnot read by ETFIQ
US estate tax filing threshold, non-resident holders$60,000
Share classDistributing

BBC is a US fund. Stock of US corporations counts as US property for a non-resident's estate. Facts from the IRS, not tax advice. How withholding and treaties work
Download all holdings

BBC top ten by weight, 11.8% of the fund, of its 131 equity positions, from the holdings filed for Jul 31, 2026. Source: the fund’s SEC filing.

ATAIBECKLEY INC ATAI 1.23%
MONOPAR THERAPEUTICS INC MNPR 1.21%
XENCOR INC XNCR 1.10%
UNIQURE NV QURE 1.06%

Source: Holdings filing (SEC Form N-PORT).

About BBC

Theme (ETFIQ, editorial)Biotech
First tradedDec 17, 2014
Already in the S&P 500, by weight (ETFIQ)0.0%
Outside the S&P 500, by weight (ETFIQ)100%
Active share vs the S&P 500 (ETFIQ)100.0%
Already in the Nasdaq-100, by weight (ETFIQ)0.0%
Active share vs the Nasdaq-100 (ETFIQ)100.0%
Top ten holdings weight11.8%
Holdings131
Holdings as of (SEC N-PORT)Jul 31, 2026
Top holdingsFIRST TRACKS BIOTHERAPEUTICS INC 1.7%, MBX BIOSCIENCES INC 1.2%, ATAIBECKLEY INC 1.2%, MONOPAR THERAPEUTICS INC 1.2%, DEFINIUM THERAPEUTICS INC 1.2%, XENCOR INC 1.1%, ZENAS BIOPHARMA INC 1.1%, UNIQURE NV 1.1%, APOGEE THERAPEUTICS INC 1.0%, VOR BIOPHARMA INC 1.0%
Net assets (SEC filing, whole fund, as filed for Jul 31, 2026)$46mReport
Benchmark (ETFIQ, from its filings)Its own holdings, as of Jul 31, 2026; no other fund tracks the LifeSci Biotechnology Clinical Trials Index, the index its prospectus names
BBC, Jul 31, 2026 to Oct 12, 2026−11.65%
Its book of Jul 31, 2026, the same days (ETFIQ, measured on 98% of the book by weight)−11.61%
Against its own holdings (ETFIQ)−0.04 pts
Stated benchmarkLifeSci Biotechnology Clinical Trials Index (from its prospectus). BBC is the only ETF ETFIQ covers that tracks it.
Below its all-time high (ETFIQ)−27.4%
Expense ratio (485BPOS XBRL, Feb 27, 2026)0.65%Report
Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ)0.65%
Closest funds by holdings overlapXBI 31%, FMED 19%, CANC 16%, WDNA 13%, IBBQ 13%
Below its all-time high27.4%, high on Feb 8, 2021
How we measure
The top ten holdings are 12% of the fund across 131 positions, as filed for Jul 31, 2026. Over the year to Nov 4, 2026 the fund returned +45.9% with distributions reinvested. It sits 27.4% below its all-time high of Feb 8, 2021.
Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. Method
IQ Investment Committee on BBC

12 seats on BBC, as of Nov 4, 2026: 2 Mixed, 7 Challenges, 3 Not enough data.

In the tradition ofJohn BogleBogle-style Low CostChallenges
In the tradition ofBenjamin GrahamGraham-style Margin of SafetyChallenges
In the tradition ofWarren Buffett & Charlie MungerBuffett & Munger-style QualityNot enough data
In the tradition ofPeter LynchLynch-style Growth at a Reasonable PriceNot enough data
In the tradition ofJohn TempletonTempleton-style Global ContrarianMixed
In the tradition ofRay DalioDalio-style All-WeatherChallenges
In the tradition ofHoward MarksMarks-style Cycles & RiskChallenges
In the tradition ofStanley DruckenmillerDruckenmiller-style Macro & LiquidityChallenges
In the tradition ofDavid SwensenSwensen-style DiversificationChallenges
In the tradition ofCathie WoodWood-style Disruptive InnovationNot enough data
In the tradition ofJesse LivermoreLivermore-style Trend FollowingChallenges
Uses ETFIQ’s measuresThe ETFIQ SkepticETFIQ’s own seatMixed
Put BBC to the committee →See all seats →No investor named is affiliated with or endorses ETFIQ. Not investment advice.

Questions people ask about BBC

How much of BBC is in S&P 500 companies?
By its holdings filed for Jul 31, 2026, 0% of BBC by weight is stocks the S&P 500 already holds. Its active share against the index is 100%, so that share is the part doing something different.
What does BBC hold?
131 positions as filed for Jul 31, 2026, with the top ten at 12% of the fund. The largest are FIRST TRACKS BIOTHERAPEUTICS INC at 1.7%, MBX BIOSCIENCES INC at 1.2%, ATAIBECKLEY INC at 1.2%.
Has BBC beaten the S&P 500?
Over the year to Nov 4, 2026 BBC returned +45.9% with distributions reinvested, against +14.8% for the S&P 500, so it finished ahead of the index by 31.1 points.
What does BBC cost?
The prospectus expense ratio is 0.65% a year. Because 100% of the fund differs from the S&P 500, the fee on that differing part works out at 0.65%.
Sources and dates
Prices, BBC and S&P 500 (SPY)Tiingo end-of-day · Nov 4, 2026
Net assets, $46mSEC filing, whole fund · Jul 31, 2026

Links are sources, not endorsements.

Cite this pageCitation, APA and Markdown

ETFIQ, BBC, thematic ETFs, data as of Nov 4, 2026. https://etfiq.com/funds/bbc

The difference bar for BBC, redrawn every trading night.

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data.

How differently the money is placed, counting weights: one minus the sum of the smaller weight of each security across the fund and the index. 100% means nothing in common; 0% means the index itself. Two funds can hold the same names and still have a high active share if they weight them very differently.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at different weights.
The weight of the ten largest holdings. Above 50% the fund is a bet on a handful of companies, whatever the theme.
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BBC: 0% of BBC's weight is in S&P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026.
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<iframe src="https://etfiq.com/embed/themes/bbc/" title="BBC: 0% of BBC&#x27;s weight is in S&amp;P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026." width="640" height="346" loading="lazy" style="border:0;max-width:100%;width:100%"></iframe>
<figcaption style="font:13px/1.5 sans-serif">BBC: 0% of BBC&#x27;s weight is in S&amp;P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026. Data: <a href="https://etfiq.com/funds/bbc">ETFIQ</a></figcaption>
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