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Data as of .

BBC vs IDNA: which is really different?

BBC and IDNA hold 9% of their weight in the same names, and BBC returned more over the year.

Virtus Biotech Clinical Trials ETF and iShares Genomics Immunology and Healthcare ETF.

0.0%BBC in the S&P 500
23.9%IDNA in the S&P 500
+95.6%BBC total return, 1 year
+73.4%IDNA total return, 1 year

ETFIQ Off-Index Score: BBC scores higher

How much of it is not the index it is sold as an alternative to?

BBC 91.8IDNA 64.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

BBC100% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 16% of the fund · 124 holdings filed Apr 30, 2026 · Nasdaq-100: 0% in0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 16% of the fund
IDNA76% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
24%76%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 46% of the fund · 62 holdings filed Sep 17, 2026 · Nasdaq-100: 7% in24%76%inoutside the S&P 500active share 99% · top ten 46% of the fund

9% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, BBC and IDNA hold 9% of their money in the same securities at the same weight.

Positions BBC and IDNA both hold, largest shared weight first
HoldingBBCIDNA
REVOLUTION MEDICINES INC1.35%3.86%
VIR BIOTECHNOLOGY INC1.13%1.34%
ARCUS BIOSCIENCES INC0.88%1.96%
ABCELLERA BIOLOGICS INC0.85%2.74%
CORVUS PHARMACEUTICALS INC1.34%0.73%
JANUX THERAPEUTICS INC0.69%0.88%
IDEAYA BIOSCIENCES INC0.63%2.95%
RIGEL PHARMACEUTICALS INC0.52%0.75%
XENCOR INC0.53%0.51%
INTELLIA THERAPEUTICS INC1.11%0.48%
CYTOMX THERAPEUTICS INC0.74%0.45%
VERASTEM INC0.42%0.57%
Only in each
Only in BBCOnly in IDNA
ERASCA INC 2.19%MODERNA 9.74%
ENLIVEN THERAPEUTICS INC 1.81%TWIST BIOSCIENCE 6.57%
TANGO THERAPEUTICS INC 1.71%GENMAB 4.09%
ORUKA THERAPEUTICS INC 1.68%BAYER AG 3.94%
SPYRE THERAPEUTICS INC 1.64%INCYTE CORP 3.64%
ALUMIS INC 1.59%REGENERON PHARMACEUTICALS 3.63%
DIANTHUS THERAPEUTICS INC 1.54%TAKEDA PHARMACEUTICAL 3.63%
KODIAK SCIENCES INC 1.35%IOVANCE BIOTHERAPEUTICS INC 3.57%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Sep 17, 2026.

Performance, window by window

BBC and IDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
BBCIDNABBCIDNABBCIDNA
3 months+6.9%+30.3%+4.7 pts+28.1 pts+9.4 pts+32.8 pts
6 months+22.7%+41.4%+4.7 pts+23.4 pts−1.5 pts+17.2 pts
1 year+95.6%+73.4%+79.0 pts+56.9 pts+73.8 pts+51.7 pts
3 years+143.8%+91.3%+65.3 pts+12.9 pts+45.6 pts−6.9 pts
Since launch+92.6%+69.7%−268.5 pts−123.9 pts−583.0 pts−242.0 pts
Open the live comparison on ETFIQ
BBC and IDNA on the same fields, as of Sep 18, 2026. Source: ETFIQ.
BBC
Virtus Biotech Clinical Trials ETF
Holds 124 stocks in biotech, 0% of its weight in S&P 500 companies
IDNA
iShares Genomics Immunology and Healthcare ETF
Holds 62 stocks in genomics and gene editing, 24% of its weight in S&P 500 companies
IssuerVirtusiShares
ThemeBiotechGenomics and gene editing
In the S&P 5000.0%23.9%
Active share vs the S&P 500100.0%99.1%
In the Nasdaq-1000.0%7.0%
Holdings12462
Top ten, share of the fund16.2%46.2%
Expense ratio0.65%0.47%
Fee for the differing part0.65%0.47%
Total return, 1 year+95.6%+73.4%
vs the S&P 500+79.0 pts+56.9 pts
vs the Nasdaq-100+73.8 pts+51.7 pts
Below its high−19.1%−24.7%
Net assets$37m$271m

BBC in plain words

By weight, 0% of BBC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 16% of the fund across 124 positions, as filed for Apr 30, 2026. Over the year to Sep 18, 2026 the fund returned +95.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 79.0 pts. It sits 19.1% below its all-time high of Feb 8, 2021.

IDNA in plain words

By weight, 24% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 46% of the fund across 62 positions, as published by its issuer for Sep 17, 2026. Over the year to Sep 18, 2026 the fund returned +73.4% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 56.9 pts. It sits 24.7% below its all-time high of Sep 2, 2021.

Questions people ask

Do BBC and IDNA hold the same stocks?
By their latest filings, 9% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBC or IDNA?
BBC has 0% of its weight in S&P 500 names and IDNA has 24%, so BBC differs more from the index.
Which is cheaper, BBC or IDNA?
BBC charges 0.65% a year and IDNA charges 0.47%, so IDNA is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

BBC against IDNA, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, BBC against IDNA, data as of Sep 18, 2026. https://etfiq.com/compare/themes/bbc-vs-idna Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources