Data as of .
IBBQ vs IDNA: which is really different?
IBBQ and IDNA hold 22% of their weight in the same names, and IDNA returned more over the year.
ETFIQ Off-Index Score: IDNA scores higher
How much of it is not the index it is sold as an alternative to?
A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed
22% of the two portfolios are the same securities at the same weight.
What they hold in common
By the books each fund has filed, IBBQ and IDNA hold 22% of their money in the same securities at the same weight.
| Holding | IBBQ | IDNA |
|---|---|---|
| Moderna Inc | 4.10% | 9.54% |
| Regeneron Pharmaceuticals Inc | 5.42% | 3.63% |
| Vertex Pharmaceuticals Inc | 7.98% | 3.34% |
| Revolution Medicines Inc | 2.72% | 3.76% |
| Incyte Corp | 1.68% | 3.60% |
| Exelixis Inc | 0.98% | 3.25% |
| BioNTech SE | 0.75% | 3.20% |
| Twist Bioscience Corp | 0.70% | 7.09% |
| Sanofi SA | 0.66% | 2.77% |
| ImmunityBio Inc | 0.60% | 2.94% |
| Caris Life Sciences Inc | 0.57% | 3.39% |
| CRISPR Therapeutics AG | 0.37% | 1.50% |
| Only in IBBQ | Only in IDNA |
|---|---|
| Amgen Inc 8.05% | BAYER AG 3.87% |
| Gilead Sciences Inc 7.89% | TAKEDA PHARMACEUTICAL 3.62% |
| Illumina Inc 2.43% | MERCK & CO INC 3.57% |
| Alnylam Pharmaceuticals Inc 2.14% | ROCHE PS PAR AG 3.09% |
| Biogen Inc 2.13% | IPSEN SA 2.88% |
| Roivant Sciences Ltd 1.92% | GLAXOSMITHKLINE 2.84% |
| Argenx SE 1.83% | ARCUS BIOSCIENCES 1.95% |
| Insmed Inc 1.74% | ONO PHARMACEUTICAL 1.57% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 19, 2026.
Performance, window by window
| Window | Total return | vs the S&P 500 | vs the Nasdaq-100 | |||
|---|---|---|---|---|---|---|
| IBBQ | IDNA | IBBQ | IDNA | IBBQ | IDNA | |
| 3 months | +15.8% | +30.3% | +13.6 pts | +28.1 pts | +18.3 pts | +32.8 pts |
| 6 months | +24.9% | +41.4% | +6.9 pts | +23.4 pts | +0.7 pts | +17.2 pts |
| 1 year | +44.6% | +73.4% | +28.0 pts | +56.9 pts | +22.8 pts | +51.7 pts |
| 3 years | +76.7% | +91.3% | −1.7 pts | +12.9 pts | −21.5 pts | −6.9 pts |
| Since launch | +42.0% | +69.7% | −51.2 pts | −123.9 pts | −76.1 pts | −242.0 pts |
| IBBQ Invesco Nasdaq Biotechnology ETF Holds 256 stocks in biotech, 39% of its weight in S&P 500 companies | IDNA iShares Genomics Immunology and Healthcare ETF Holds 62 stocks in genomics and gene editing, 24% of its weight in S&P 500 companies | |
|---|---|---|
| Issuer | Invesco | iShares |
| Theme | Biotech | Genomics and gene editing |
| In the S&P 500 | 38.6% | 23.9% |
| Active share vs the S&P 500 | 99.0% | 99.1% |
| In the Nasdaq-100 | 33.2% | 7.0% |
| Holdings | 256 | 62 |
| Top ten, share of the fund | 44.8% | 46.2% |
| Expense ratio | 0.19% | 0.47% |
| Fee for the differing part | 0.19% | 0.47% |
| Total return, 1 year | +44.6% | +73.4% |
| vs the S&P 500 | +28.0 pts | +56.9 pts |
| vs the Nasdaq-100 | +22.8 pts | +51.7 pts |
| Below its high | −5.8% | −24.7% |
| Net assets | $96m | $271m |
IBBQ in plain words
By weight, 39% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 256 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +44.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 28.0 pts. It sits 5.8% below its all-time high of Aug 19, 2026.
IDNA in plain words
By weight, 24% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 46% of the fund across 62 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +73.4% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 56.9 pts. It sits 24.7% below its all-time high of Sep 2, 2021.
Questions people ask
- Do IBBQ and IDNA hold the same stocks?
- By their latest filings, 22% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
- Which is more different from the S&P 500, IBBQ or IDNA?
- IBBQ has 39% of its weight in S&P 500 names and IDNA has 24%, so IDNA differs more from the index.
- Which is cheaper, IBBQ or IDNA?
- IBBQ charges 0.19% a year and IDNA charges 0.47%, so IBBQ is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBBQ against IDNA, data as of Sep 18, 2026. https://etfiq.com/compare/themes/ibbq-vs-idna Free to use with attribution; the underlying files are at Open data.