Do IBBQ and IDNA hold the same stocks?

By their latest filings, 24% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, IBBQ or IDNA?

IBBQ has 42% of its weight in S&P 500 names and IDNA has 27%, so IDNA differs more from the index.

Which is cheaper, IBBQ or IDNA?

IBBQ charges 0.19% a year and IDNA charges 0.47%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

IBBQ vs IDNA: Holdings Overlap & Returns

Share on X Download as PDF

Over the year to Nov 4, 2026, IBBQ returned +42.7% to IDNA's +81.1%; 24% of their weight is in the same names.

askIQ about this page

askIQ about IBBQ and IDNA

Net assets on Nov 3, 2026: $121m for Invesco Nasdaq Biotechnology ETF and $340m for iShares Genomics Immunology and Healthcare ETF.

IBBQ on its own →IDNA on its own →

At a glance

42.5%

IBBQ in the S&P 500

27.4%

IDNA in the S&P 500

+42.7%

IBBQ total return, 1 year

+81.1%

IDNA total return, 1 year

IBBQ · 1 year to Nov 4, 2026 58% of its weight is outside the S&P 500

43% of IBBQ's weight is in S&P 500 companies and 58% is outside the index. Holdings as of Nov 3, 2026.

IDNA · 1 year to Nov 4, 2026 73% of its weight is outside the S&P 500

27% of IDNA's weight is in S&P 500 companies and 73% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

IBBQ costs 0.28 points a year less; their one-year returns differ by 38.4 points; IDNA is 2.8 times larger.

IBBQ vs IDNA: Holdings Overlap & Returns
Measure	IBBQ	IDNA
Return
Measure	IBBQ	IDNA
Total return, 1 year	+42.7%	+81.1%
Drawdown
Measure	IBBQ	IDNA
Below its all-time high		16.5%, high on Sep 2, 2021
Benchmark
Measure	IBBQ	IDNA
What it tracks	Biotech	Genomics and gene editing
Cost and size
Measure	IBBQ	IDNA
Expense ratio	0.19%	0.47%
Net assets, as of Nov 3, 2026	$121m	$340m
Holdings
Measure	IBBQ	IDNA
Holdings in common	24%

Method

Risk and return

Jun 18, 2021 to Oct 30, 2026 · 280 weekly returns

IBBQ IDNA

Return

Total return edge IBBQ +52.1% −6.3%

Annualized edge IBBQ +8.1% −1.2%

Price return edge IBBQ +44.3% −10.7%

Risk

Volatility edge IBBQ 21.2% 28.6%

Max drawdown edge IBBQ −35.4% −68.1%

Risk-adjusted

Sharpe edge IBBQ 0.30 −0.03

Sortino edge IBBQ 0.44 −0.04

Calmar edge IBBQ 0.23 −0.02

Reading

From Jun 2021 to Oct 2026, IBBQ returned more: +52.1% to −6.3%. IBBQ swung less: 21.2% to 28.6%. IBBQ fell less at its worst: −35.4% to −68.1%.

Full scorecard

9 measures, with how each is measured Open ↓

Risk and return: IBBQ vs IDNA: Holdings Overlap & Returns
Measure	IBBQ	IDNA	Edge	How it is measured
Return
Total return	+52.1%	−6.3%	IBBQ	Price change plus distributions, reinvested.
Annualized	+8.1%	−1.2%	IBBQ	Total return as a yearly rate.
Price return	+44.3%	−10.7%	IBBQ	Price change alone, distributions left out.
Risk
Volatility	21.2%	28.6%	IBBQ	Spread of weekly returns, annualized. Lower is steadier.
Downside deviation	14.6%	19.4%	IBBQ	Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown	−35.4%	−68.1%	IBBQ	Deepest fall from a high to the low after it.
Risk-adjusted
Sharpe	0.30	−0.03	IBBQ	Return above Treasury bills per unit of volatility.
Sortino	0.44	−0.04	IBBQ	Return above Treasury bills per unit of downside deviation.
Calmar	0.23	−0.02	IBBQ	Annualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 280 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

24%

By the books each fund has filed, IBBQ and IDNA hold 24% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026.

50%

0 half 100%

half

24% in common

Positions both hold · largest shared weight first IBBQ IDNA

Moderna Inc 5.85% 13.33%

Regeneron Pharmaceuticals Inc 6.31% 4.24%

Vertex Pharmaceuticals Inc 7.65% 3.29%

Revolution Medicines Inc 2.67% 3.60%

Incyte Corp 1.53% 3.18%

Exelixis Inc 1.15% 3.80%

BioNTech SE 0.65% 2.73%

Sanofi SA 0.63% 2.79%

Twist Bioscience Corp 0.60% 5.61%

Caris Life Sciences Inc 0.59% 3.50%

ImmunityBio Inc 0.56% 2.71%

Genmab A/S 0.34% 6.26%

Only in one fund ↓

Only in IBBQ

Gilead Sciences Inc 8.97%

Amgen Inc 8.42%

Biogen Inc 2.36%

Illumina Inc 2.31%

Royalty Pharma PLC 1.90%

Roivant Sciences Ltd 1.67%

United Therapeutics Corp 1.66%

Argenx SE 1.57%

Only in IDNA

BAYER AG 3.85%

TAKEDA PHARMACEUTICAL 3.77%

MERCK & CO INC 3.32%

ROCHE PS PAR AG 3.20%

GLAXOSMITHKLINE 2.62%

IPSEN SA 2.61%

ONO PHARMACEUTICAL 1.43%

ARCUS BIOSCIENCES 1.37%

Check overlap with more funds →

Window by window

Window by window: IBBQ vs IDNA: Holdings Overlap & Returns
	Total return
Window	IBBQ	IDNA
3 months	+12.7%	+32.4%
6 months	+23.7%	+45.6%
1 year	+42.7%	+81.1%
3 years	+96.2%	+134.8%
Since launchNot the same days: IBBQ Jun 2021 · IDNA Jun 2019	+51.9%	+88.1%

Open this comparison in the app →

Side by side

IBBQ Invesco Nasdaq Biotechnology ETF · Holds 254 stocks in biotech, 42% of its weight in S&P 500 companies IDNA iShares Genomics Immunology and Healthcare ETF · Holds 52 stocks in genomics and gene editing, 27% of its weight in S&P 500 companies

Issuer Invesco iShares

Theme Biotech Genomics and gene editing

In the S&P 500 42.5% 27.4%

Active share vs the S&P 500 99.0% 99.1%

In the Nasdaq-100 32.7% 7.5%

Holdings 254 52

Top ten, share of the fund 48.1% 51.3%

Expense ratio 0.19% 0.47%

Fee for the differing part 0.19% 0.47%

Total return, 1 year +42.7% +81.1%

vs its benchmark not measured not measured

Below its high 0.0% −16.5%

Net assets, as of Nov 3, 2026 $121m $340m

As of Nov 4, 2026. Source: ETFIQ.

24% of the two portfolios are the same securities at the same weight.

Client brief:

The two-page PDF for this pair is coming. Save the comparison to follow its changes. Free. It needs an email sign-in, once.

Your saved page · Privacy.

Alert

About each fund

IBBQ

By weight, 42% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 48% of the fund across 254 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +42.7% with distributions reinvested.

IDNA

By weight, 27% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 51% of the fund across 52 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +81.1% with distributions reinvested. It sits 16.5% below its all-time high of Sep 2, 2021.

Questions people ask

Do IBBQ and IDNA hold the same stocks?: By their latest filings, 24% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, IBBQ or IDNA?: IBBQ has 42% of its weight in S&P 500 names and IDNA has 27%, so IDNA differs more from the index.
Which is cheaper, IBBQ or IDNA?: IBBQ charges 0.19% a year and IDNA charges 0.47%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Other comparisons

IBBQ vs ARKG IBBQ vs GNOM IBBQ vs GNMX IBBQ vs BBP IDNA vs BBC IDNA vs IBB IDNA vs BBP IDNA vs PBE

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →IBBQ on its own →IDNA on its own →IBBQ dividend history →IBBQ holdings →IDNA dividend history →IDNA holdings →Method →Standards and sources →

Sources and dates

IBBQ filings on SEC EDGAR ↗

IBBQ prospectus with the expense ratio (SEC) ↗

Invesco page for IBBQ ↗

IDNA filings on SEC EDGAR ↗

IDNA prospectus with the expense ratio (SEC) ↗

iShares page for IDNA ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, IBBQ against IDNA, data as of Nov 4, 2026. https://etfiq.com/compare/themes/ibbq-vs-idna

Open data →

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.