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Data as of .

GNMX vs IBBQ: which is really different?

GNMX and IBBQ hold 30% of their weight in the same names.

Corgi Genomics & Precision Medicine ETF and Invesco Nasdaq Biotechnology ETF.

26.7%GNMX in the S&P 500
38.6%IBBQ in the S&P 500
+41.2%GNMX total return, 1 year
+44.6%IBBQ total return, 1 year

ETFIQ Off-Index Score: GNMX scores higher

How much of it is not the index it is sold as an alternative to?

GNMX 67.4IBBQ 61.70.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

GNMX73% of its weight is outside the S&P 500 · 3 months to Sep 18, 2026
27%73%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 45% of the fund · 58 holdings filed Sep 18, 2026 · Nasdaq-100: 9% in27%73%inoutside the S&P 500active share 99% · top ten 45% of the fund
IBBQ61% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
39%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 45% of the fund · 256 holdings filed Sep 19, 2026 · Nasdaq-100: 33% in39%61%in the S&P 500outside the S&P 500active share 99% · top ten 45% of the fund

30% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, GNMX and IBBQ hold 30% of their money in the same securities at the same weight.

Positions GNMX and IBBQ both hold, largest shared weight first
HoldingGNMXIBBQ
Vertex Pharmaceuticals Inc5.89%7.98%
Moderna Inc7.05%4.10%
Revolution Medicines Inc3.27%2.72%
Illumina Inc4.36%2.43%
Alnylam Pharmaceuticals Inc2.64%2.14%
Incyte Corp2.90%1.68%
Guardant Health Inc3.86%1.59%
Tempus AI Inc2.02%0.91%
BioMarin Pharmaceutical Inc2.22%0.83%
Twist Bioscience Corp2.86%0.70%
Krystal Biotech Inc1.86%0.67%
Arrowhead Pharmaceuticals Inc1.50%0.63%
Only in each
Only in GNMXOnly in IBBQ
Thermo Fisher Scientific Inc 8.62%Amgen Inc 8.05%
First American Government Obligations Fu 2.62%Gilead Sciences Inc 7.89%
Bio-Techne Corp 2.20%Regeneron Pharmaceuticals Inc 5.42%
QIAGEN NV 1.86%Biogen Inc 2.13%
CareDx Inc 1.60%Roivant Sciences Ltd 1.92%
NeoGenomics Inc 1.60%Argenx SE 1.83%
Schrodinger Inc/United States 1.46%Insmed Inc 1.74%
GeneDx Holdings Corp 1.12%Royalty Pharma PLC 1.74%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 19, 2026.

Performance, window by window

GNMX and IBBQ over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
GNMXIBBQGNMXIBBQGNMXIBBQ
3 months+29.7%+15.8%+27.4 pts+13.6 pts+32.2 pts+18.3 pts
6 monthsnot published+24.9%not published+6.9 ptsnot published+0.7 pts
1 yearnot published+44.6%not published+28.0 ptsnot published+22.8 pts
3 yearsnot published+76.7%not published−1.7 ptsnot published−21.5 pts
Since launch+41.2%+42.0%+36.9 pts−51.2 pts+37.4 pts−76.1 pts
Open the live comparison on ETFIQ
GNMX and IBBQ on the same fields, as of Sep 18, 2026. Source: ETFIQ.
GNMX
Corgi Genomics & Precision Medicine ETF
Holds 58 stocks in genomics and gene editing, 27% of its weight in S&P 500 companies
IBBQ
Invesco Nasdaq Biotechnology ETF
Holds 256 stocks in biotech, 39% of its weight in S&P 500 companies
IssuerCorgiInvesco
ThemeGenomics and gene editingBiotech
In the S&P 50026.7%38.6%
Active share vs the S&P 50099.4%99.0%
In the Nasdaq-1008.5%33.2%
Holdings58256
Top ten, share of the fund45.1%44.8%
Expense ratio0.35%0.19%
Fee for the differing part0.35%0.19%
Total return, 1 year+41.2% (since launch on May 6, 2026)+44.6%
vs the S&P 500+36.9 pts+28.0 pts
vs the Nasdaq-100+37.4 pts+22.8 pts
Below its high−1.0%−5.8%
Net assets$3m$96m

GNMX in plain words

By weight, 27% of GNMX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 58 positions, as published by its issuer for Sep 18, 2026. Since it launched on May 6, 2026 the fund returned +41.2% with distributions reinvested against +4.3% for the S&P 500, so a holder was ahead by 36.9 pts.

IBBQ in plain words

By weight, 39% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 256 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +44.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 28.0 pts. It sits 5.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do GNMX and IBBQ hold the same stocks?
By their latest filings, 30% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, GNMX or IBBQ?
GNMX has 27% of its weight in S&P 500 names and IBBQ has 39%, so GNMX differs more from the index.
Which is cheaper, GNMX or IBBQ?
GNMX charges 0.35% a year and IBBQ charges 0.19%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

GNMX against IBBQ, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, GNMX against IBBQ, data as of Sep 18, 2026. https://etfiq.com/compare/themes/gnmx-vs-ibbq Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources