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Data as of Nov 4, 2026.

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Thematic ETFs

GNMX vs PBE: Holdings Overlap & Returns

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GNMX and PBE hold 21% of their weight in the same names.

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Net assets: $1.3m on Nov 4, 2026 for Corgi Genomics & Precision Medicine ETF, and $442m on Nov 3, 2026 for Invesco Biotechnology & Genome ETF.

GNMX on its own →PBE on its own →
At a glance
31.0%
GNMX in the S&P 500
32.3%
PBE in the S&P 500
+48.3%
GNMX total return, 6 months
+44.2%
PBE total return, 1 year
GNMX · 6 months to Nov 4, 2026 69% of its weight is outside the S&P 500
69% of its weight is outside the S&P 50031% of GNMX's weight is in S&P 500 companies and 69% is outside the index. Holdings as of Nov 4, 2026.31%69%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 49% of the fund · 57 holdings as published by its issuer for Nov 4, 2026 · Nasdaq-100: 8% in69% of its weight is outside the S&P 50031% of GNMX's weight is in S&P 500 companies and 69% is outside the index. Holdings as of Nov 4, 2026.31%69%inoutside the S&P 500active share 99% · Nasdaq-100: 8% in

31% of GNMX's weight is in S&P 500 companies and 69% is outside the index. Holdings as of Nov 4, 2026.

PBE · 1 year to Nov 4, 2026 68% of its weight is outside the S&P 500
68% of its weight is outside the S&P 50032% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.32%68%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 49% of the fund · 32 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 21% in68% of its weight is outside the S&P 50032% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.32%68%inoutside the S&P 500active share 99% · Nasdaq-100: 21% in

32% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

GNMX costs 0.24 points a year less; PBE is far larger, $442m against $1.3m.

GNMX vs PBE: Holdings Overlap & Returns
MeasureGNMXPBE
Return
Total return, 1 yearnot published+44.2%
Benchmark
What it tracksGenomics and gene editingBiotech
Cost and size
Expense ratio0.35%0.59%
Net assets, as of Nov 3, 2026$1.3m$442m
Holdings
Holdings in common21%

Method

What they share

21%

By the books each fund has filed, GNMX and PBE hold 21% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026 and Nov 4, 2026.

0 half 100%

half

21% in common

Positions both hold · largest shared weight first GNMX PBE
Vertex Pharmaceuticals Inc 6.04% 4.62%
Illumina Inc 3.92% 5.10%
Moderna Inc 11.24% 3.78%
Incyte Corp 2.70% 2.38%
QIAGEN NV 2.08% 3.03%
BioMarin Pharmaceutical Inc 1.89% 2.21%
Veracyte Inc 1.46% 3.00%
Sarepta Therapeutics Inc 0.84% 2.57%
Only in one fund ↓
Only in GNMX
Thermo Fisher Scientific Inc 8.88%
Genmab A/S 4.39%
Guardant Health Inc 3.45%
Revolution Medicines Inc 3.24%
10X Genomics Inc 2.87%
CareDx Inc 2.43%
Twist Bioscience Corp 2.32%
GRAIL Inc 2.26%
Only in PBE
Regeneron Pharmaceuticals Inc 5.62%
Natera Inc 5.56%
Biogen Inc 5.43%
Gilead Sciences Inc 5.42%
Royalty Pharma PLC 5.15%
Amgen Inc 5.02%
Exelixis Inc 3.35%
Halozyme Therapeutics Inc 3.09%
Check overlap with more funds →

Window by window

Window by window: GNMX vs PBE: Holdings Overlap & Returns
Total return
WindowGNMXPBE
3 months+24.3%+14.2%
6 months+48.3%+27.1%
1 year–+44.2%
3 years–+90.4%
Since launchNot the same days: GNMX May 2026 · PBE Jun 2005+48.3%+650.5%

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Side by side

GNMX Corgi Genomics & Precision Medicine ETF · Holds 57 stocks in genomics and gene editing, 31% of its weight in S&P 500 companies PBE Invesco Biotechnology & Genome ETF · Holds 32 stocks in biotech, 32% of its weight in S&P 500 companies
Issuer Corgi Invesco
Theme Genomics and gene editing Biotech
In the S&P 500 31.0% 32.3%
Active share vs the S&P 500 99.4% 99.0%
In the Nasdaq-100 7.7% 20.7%
Holdings 57 32
Top ten, share of the fund 49.2% 49.1%
Expense ratio 0.35% 0.59%
Fee for the differing part 0.35% 0.60%
Total return, 1 year +48.3% (since launch, May 6, 2026) +44.2%
vs its benchmark not measured not measured
Below its high −4.2% 0.0%
Net assets, GNMX as of Nov 4, 2026 and PBE as of Nov 3, 2026 $1.3m $442m

As of Nov 4, 2026. Source: ETFIQ.

21% of the two portfolios are the same securities at the same weight.

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About each fund
GNMX

By weight, 31% of GNMX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 49% of the fund across 57 positions, as published by its issuer for Nov 4, 2026. Since it first traded on May 6, 2026 the fund returned +48.3% with distributions reinvested.

PBE

By weight, 32% of PBE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 49% of the fund across 32 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +44.2% with distributions reinvested.

Questions people ask

Do GNMX and PBE hold the same stocks?
By their latest filings, 21% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, GNMX or PBE?
GNMX has 31% of its weight in S&P 500 names and PBE has 32%, so GNMX differs more from the index.
Which is cheaper, GNMX or PBE?
GNMX charges 0.35% a year and PBE charges 0.59%, so GNMX is cheaper. Fees come from each fund's prospectus.
Other comparisons
GNMX vs PBPHGNMX vs IBBQGNMX vs FBTGNMX vs XBIPBE vs GNOMPBE vs IDNAPBE vs ARKGPBE vs BBC
Where to next
All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →GNMX on its own →PBE on its own →GNMX holdings →PBE dividend history →PBE holdings →Method →Standards and sources →
Sources and dates
GNMX filings on SEC EDGAR ↗
GNMX prospectus with the expense ratio (SEC) ↗
Corgi website ↗
PBE filings on SEC EDGAR ↗
PBE prospectus with the expense ratio (SEC) ↗
Invesco page for PBE ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, GNMX against PBE, data as of Nov 4, 2026. https://etfiq.com/compare/themes/gnmx-vs-pbe

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.