PBE Invesco Biotechnology & Genome ETF
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Over the year to Oct 28, 2026, PBE returned 40.1%.
Promise check: Not measuredIts theme exposure is measured once ETFIQ defines its theme company by company.
PBE risk and return scorecard
vs its own holdings
Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data
Money in and out
Net fund flows · Oct 27, 2026What you earned
What did you actually buy?
Biotech · holdings as of Oct 27, 2026More on PBE
Every number below is on this page. Open what you need.Price, 1 year
$101.87+1.1%1 day, priceClose, Oct 28, 2026
Price only. Total return over the same days, distributions reinvested, was +40.1%. Computed by ETFIQ from Tiingo daily prices.
Source: Tiingo end-of-day prices. Data as of Oct 28, 2026. Updated every trading night. Report a data error
| Window | Total return | S&P 500 (SPY) |
|---|---|---|
| 1M Sep 28 – Oct 28, 2026 | +4.7% | +0.9% |
| 3M Jul 29 – Oct 28, 2026 | +11.8% | +6.1% |
| 6M Apr 29 – Oct 28, 2026 | +31.0% | +9.1% |
| YTD Dec 31, 2025 – Oct 28, 2026 | +25.4% | +14.1% |
| 1Y Oct 28, 2025 – Oct 28, 2026 | +40.1% | +13.6% |
| 3Y Oct 27, 2023 – Oct 28, 2026 | +98.3% | +95.0% |
| 5Y Oct 29, 2021 – Oct 28, 2026 | +38.8% | +79.8% |
| 10Y Oct 28, 2016 – Oct 28, 2026 | +179.8% | +325.8% |
| Since launch Jun 23, 2005 – Oct 28, 2026 | +630.4% | +850.3% |
| Since launch, annualised Jun 23, 2005 – Oct 28, 2026 | +9.8% | – |
Total returns, distributions reinvested.
Source: Tiingo end-of-day prices, with distributions reinvested.
Money in and out
Daily data · as of Oct 27, 2026PBE: in the 17 trading days to Oct 27, 2026, net $1.9m went out, from 14 counts.
Oct 27, 2026
Oct 21, 2026 to Oct 27, 2026
Aug 1, 2025 to Jul 31, 2026
monthly, from SEC filings
Aug 1, 2023 to Jul 31, 2026
monthly, from SEC filings
Aug 1, 2021 to Jul 31, 2026
monthly, from SEC filings
monthly, from SEC filings
PBE, net flow each trading day over the 65 sessions from Jul 28, 2026 to Oct 27, 2026: money came in on 1 day and went out on 2 days, of the 14 days with daily data; the other 51 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.
In on 1 day, out on 2. 51 days missing.
PBE, net flow each trading day over the 251 sessions from Oct 28, 2025 to Oct 27, 2026: money came in on 1 day and went out on 2 days, of the 14 days with daily data; the other 237 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.
In on 1 day, out on 2. 237 days missing.
PBE, net flow each trading day over the 400 sessions from Mar 26, 2025 to Oct 27, 2026: money came in on 1 day and went out on 2 days, of the 14 days with daily data; the other 386 have none. Before Oct 6, 2026 ETFIQ has the fund’s monthly data only, from SEC filings: that span is shaded and draws no bars, and its months are in the month by month list.
In on 1 day, out on 2. 386 days missing.
Daily data starts Oct 6, 2026.
How this is computed
Computed by ETFIQ from Invesco’s daily data: each day’s change in shares outstanding times the previous day’s net asset value. Percentages are of net assets at the start of each window. Numbers are net: money in less money out. Every day and month ETFIQ holds for PBE, back to Aug 2019, is in its flows file. Flows across every fund · How these flows are computed · Compare PBE with other funds in the flows tool
Every trading day, last 3 months14 days
Most recent first.
Week by week, last year4 weeks
Net flow into PBE each week, Oct 6, 2026 to Oct 27, 2026, most recent first, each week named by its last trading day with data. Computed by ETFIQ.
Month by month, money in and money outSep 2023 to Oct 2026
PBE, money in and money out each month from Sep 2023 to Jul 2026: two bars a month, money in above the line and money out below. Every bar is from PBE’s SEC filings (N-PORT item B.6). Oct 2026 is still in progress, so it is in the list and not drawn. Of the 36 months listed, money came in on net in 11 and went out in 25.
Every bar is from PBE’s SEC filings (N-PORT item B.6). Of the 36 months listed, money came in on net in 11 and went out in 25.
Most recent first.
How this is computed
N-PORT months: money in is sales plus reinvestments; money out is redemptions. Months summed from daily data: money in adds the days money came in; money out adds the days it went out.
N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.
Source: ETFIQ, from the fund’s daily share counts and net asset values, and its SEC N-PORT filings. Data as of Oct 27, 2026. Last checked Oct 29, 2026.
PBE key stats
Trading
as of Oct 27, 2026
PBE top ten by weight, 49.0% of the fund, of its 32 equity positions, from the holdings published by its issuer for Oct 27, 2026. Source: the issuer’s own daily file.
Source: Invesco’s daily holdings file. Updated each trading day. Last checked Oct 28, 2026.
About PBE
12 seats on PBE, as of Oct 28, 2026: 1 Supports, 1 Mixed, 7 Challenges, 3 Not enough data.
Questions people ask about PBE
- How much of PBE is in S&P 500 companies?
- By its holdings published by its issuer for Oct 27, 2026, 31% of PBE by weight is stocks the S&P 500 already holds. Its active share against the index is 99%, so that share is the part doing something different.
- What does PBE hold?
- 32 positions as published by its issuer for Oct 27, 2026, with the top ten at 49% of the fund. The largest are Illumina Inc at 6.1%, Natera Inc at 6.0%, Biogen Inc at 5.6%.
- Has PBE beaten the S&P 500?
- Over the year to Oct 28, 2026 PBE returned +40.1% with distributions reinvested, against +13.6% for the S&P 500, so it finished ahead of the index by 26.5 points.
- What does PBE cost?
- The prospectus expense ratio is 0.59% a year. Because 99% of the fund differs from the S&P 500, the fee on that differing part works out at 0.60%.
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ETFIQ, PBE, thematic ETFs, data as of Oct 28, 2026. https://etfiq.com/funds/pbe
ETFIQ. (Oct 28, 2026). PBE, thematic ETFs. Retrieved from https://etfiq.com/funds/pbe
[PBE, thematic ETFs (ETFIQ, Oct 28, 2026)](https://etfiq.com/funds/pbe)
The difference bar for PBE, redrawn every trading night.
Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data.
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<figure style="margin:0;max-width:640px">
<a href="https://etfiq.com/funds/pbe"><img src="https://etfiq.com/assistant/api/embed/themes/pbe.svg" alt="PBE: 31% of PBE's weight is in S&P 500 companies and 69% is outside the index. Holdings as of Oct 27, 2026." width="640" style="max-width:100%;height:auto"></a>
<figcaption style="font:13px/1.5 sans-serif">PBE: 31% of PBE's weight is in S&P 500 companies and 69% is outside the index. Holdings as of Oct 27, 2026. Data: <a href="https://etfiq.com/funds/pbe">ETFIQ</a></figcaption>
</figure>The day's ETF flows, a comparison and one number. Every trading morning. About the Daily
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