Data as of Nov 4, 2026.

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Thematic ETFs

BBH vs PBE: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, BBH returned +47.2% to PBE's +44.2%; 43% of their weight is in the same names.

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Net assets on Nov 3, 2026: $525m for VanEck Biotech ETF and $442m for Invesco Biotechnology & Genome ETF.

At a glance
64.4%
BBH in the S&P 500
32.3%
PBE in the S&P 500
+47.2%
BBH total return, 1 year
+44.2%
PBE total return, 1 year
BBH · 1 year to Nov 4, 2026 36% of its weight is outside the S&P 500
36% of its weight is outside the S&P 50064% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.64%36%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 74% of the fund · 25 holdings as published by its issuer for Nov 2, 2026 · Nasdaq-100: 49% in36% of its weight is outside the S&P 50064% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.64%36%in the S&P 500outsideactive share 99% · Nasdaq-100: 49% in

64% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.

PBE · 1 year to Nov 4, 2026 68% of its weight is outside the S&P 500
68% of its weight is outside the S&P 50032% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.32%68%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 49% of the fund · 32 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 21% in68% of its weight is outside the S&P 50032% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.32%68%inoutside the S&P 500active share 99% · Nasdaq-100: 21% in

32% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

BBH costs 0.24 points a year less; their one-year returns differ by 3.0 points; BBH is 1.2 times larger.

BBH vs PBE: Holdings Overlap & Returns
MeasureBBHPBE
Return
Total return, 1 year+47.2%+44.2%
Benchmark
What it tracksBiotechBiotech
Cost and size
Expense ratio0.35%0.59%
Net assets, as of Nov 3, 2026$525m$442m
Holdings
Holdings in common43%

Method

Risk and return

Dec 30, 2011 to Oct 30, 2026 · 774 weekly returns
BBH PBE
Return
Total return edge BBH +644.8% +437.2%
Annualized edge BBH +14.4% +12.0%
Price return edge BBH +608.2% +411.0%
Risk
Volatility edge BBH (slight) 22.2% 24.0%
Max drawdown edge BBH −37.7% −42.4%
Risk-adjusted
Sharpe edge BBH 0.64 0.52
Sortino edge BBH 0.96 0.77
Calmar edge BBH 0.38 0.28
Reading

From Dec 2011 to Oct 2026, BBH returned more: +644.8% to +437.2%. BBH swung slightly less: 22.2% to 24.0%. BBH fell less at its worst: −37.7% to −42.4%.

Full scorecard

9 measures, with how each is measured
Open ↓
Risk and return: BBH vs PBE: Holdings Overlap & Returns
MeasureBBHPBEEdgeHow it is measured
Return
Total return+644.8%+437.2%BBHPrice change plus distributions, reinvested.
Annualized+14.4%+12.0%BBHTotal return as a yearly rate.
Price return+608.2%+411.0%BBHPrice change alone, distributions left out.
Risk
Volatility22.2%24.0%BBH (slight)Spread of weekly returns, annualized. Lower is steadier.
Downside deviation14.9%16.2%BBH (slight)Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.7%−42.4%BBHDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.640.52BBHReturn above Treasury bills per unit of volatility.
Sortino0.960.77BBHReturn above Treasury bills per unit of downside deviation.
Calmar0.380.28BBHAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 774 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

43%

By the books each fund has filed, BBH and PBE hold 43% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026.

0 half 100%

half

43% in common

Positions both hold · largest shared weight first BBH PBE
Regeneron Pharmaceuticals Inc 7.99% 5.62%
Gilead Sciences Inc 14.17% 5.42%
Amgen Inc 16.53% 5.02%
Vertex Pharmaceuticals Inc 7.98% 4.62%
Natera Inc 4.44% 5.56%
Moderna Inc 6.88% 3.78%
Illumina Inc 3.37% 5.10%
Biogen Inc 2.88% 5.43%
United Therapeutics Corp 2.38% 3.05%
Incyte Corp 2.07% 2.38%
Neurocrine Biosciences Inc 1.55% 2.82%
Qiagen Nv 1.02% 3.03%
Only in one fund ↓
Only in BBH
Iqvia Holdings Inc 4.18%
Argenx Se 4.13%
Revolution Medicines Inc 3.82%
Guardant Health Inc 2.83%
Beone Medicines Ltd 2.56%
Insmed Inc 1.85%
Charles River Laboratories Internationa 1.71%
Alnylam Pharmaceuticals Inc 1.68%
Only in PBE
Royalty Pharma PLC 5.15%
Exelixis Inc 3.35%
Halozyme Therapeutics Inc 3.09%
Veracyte Inc 3.00%
TG Therapeutics Inc 2.88%
Novavax Inc 2.69%
Legend Biotech Corp 2.65%
Repligen Corp 2.58%
Check overlap with more funds →

Window by window

Window by window: BBH vs PBE: Holdings Overlap & Returns
Total return
WindowBBHPBE
3 months+24.3%+14.2%
6 months+38.3%+27.1%
1 year+47.2%+44.2%
3 years+75.4%+90.4%
Since launchNot the same days: BBH Dec 2011 · PBE Jun 2005+680.5%+650.5%

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Side by side

BBH VanEck Biotech ETF · Holds 25 stocks in biotech, 64% of its weight in S&P 500 companies PBE Invesco Biotechnology & Genome ETF · Holds 32 stocks in biotech, 32% of its weight in S&P 500 companies
Theme Biotech Biotech
In the S&P 500 64.4% 32.3%
Active share vs the S&P 500 99.0% 99.0%
In the Nasdaq-100 49.1% 20.7%
Holdings 25 32
Top ten, share of the fund 73.5% 49.1%
Expense ratio 0.35% 0.59%
Fee for the differing part 0.35% 0.60%
Total return, 1 year +47.2% +44.2%
vs its benchmark not measured not measured
Below its high 0.0% 0.0%
Net assets, as of Nov 3, 2026 $525m $442m

As of Nov 4, 2026. Source: ETFIQ.

43% of the two portfolios are the same securities at the same weight.

Client brief:

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About each fund
BBH

By weight, 64% of BBH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 74% of the fund across 25 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +47.2% with distributions reinvested.

PBE

By weight, 32% of PBE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 49% of the fund across 32 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +44.2% with distributions reinvested.

Questions people ask

Do BBH and PBE hold the same stocks?
By their latest filings, 43% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBH or PBE?
BBH has 64% of its weight in S&P 500 names and PBE has 32%, so BBH differs more from the index.
Which is cheaper, BBH or PBE?
BBH charges 0.35% a year and PBE charges 0.59%, so BBH is cheaper. Fees come from each fund's prospectus.
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ETFIQ, BBH against PBE, data as of Nov 4, 2026. https://etfiq.com/compare/themes/bbh-vs-pbe

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