Do PBE and PBPH hold the same stocks?

By their latest filings, 18% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, PBE or PBPH?

PBE has 32% of its weight in S&P 500 names and PBPH has 59%, so PBE differs more from the index.

Which is cheaper, PBE or PBPH?

PBE charges 0.59% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

PBE vs PBPH: Holdings Overlap & Returns

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PBE and PBPH hold 18% of their weight in the same names.

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Net assets: $442m on Nov 3, 2026 for Invesco Biotechnology & Genome ETF, and $952m on Jul 31, 2026 for Portfolio Building Block World Pharma and Biotech Index ETF.

PBE on its own →PBPH on its own →

At a glance

32.3%

PBE in the S&P 500

59.2%

PBPH in the S&P 500

+44.2%

PBE total return, 1 year

+27.0%

PBPH total return, since launch, Nov 25, 2025

PBE · 1 year to Nov 4, 2026 68% of its weight is outside the S&P 500

32% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.

PBPH · 6 months to Nov 4, 2026 41% of its weight is outside the S&P 500

59% of PBPH's weight is in S&P 500 companies and 41% is outside the index. Holdings as of Jul 31, 2026.

Pair scorecard

PBPH costs 0.46 points a year less.

PBE vs PBPH: Holdings Overlap & Returns
Measure	PBE	PBPH
Return
Measure	PBE	PBPH
Total return, 1 year	+44.2%	not published
Benchmark
Measure	PBE	PBPH
What it tracks	Biotech	Biotech
Cost and size
Measure	PBE	PBPH
Expense ratio	0.59%	0.13%
Net assets, PBE as of Nov 3, 2026 and PBPH as of Jul 31, 2026	$442m	$952m
Holdings
Measure	PBE	PBPH
Holdings in common	18%

Method

What they share

18%

By the books each fund has filed, PBE and PBPH hold 18% of their money in the same securities at the same weight. Holdings dated Jul 31, 2026 and Nov 3, 2026.

50%

0 half 100%

half

18% in common

Positions both hold · largest shared weight first PBE PBPH

Amgen Inc 5.02% 4.63%

Gilead Sciences Inc 5.42% 3.77%

Vertex Pharmaceuticals Inc 4.62% 2.82%

Regeneron Pharmaceuticals Inc 5.62% 1.79%

Natera Inc 5.56% 0.85%

Illumina Inc 5.10% 0.72%

Biogen Inc 5.43% 0.70%

Incyte Corp 2.38% 0.56%

United Therapeutics Corp 3.05% 0.51%

Royalty Pharma PLC 5.15% 0.51%

Moderna Inc 3.78% 0.45%

Neurocrine Biosciences Inc 2.82% 0.39%

Only in one fund ↓

Only in PBE

Halozyme Therapeutics Inc 3.09%

QIAGEN NV 3.03%

Veracyte Inc 3.00%

TG Therapeutics Inc 2.88%

Novavax Inc 2.69%

Legend Biotech Corp 2.65%

Repligen Corp 2.58%

Sarepta Therapeutics Inc 2.57%

Only in PBPH

ELI LILLY & COMPANY 15.20%

JOHNSON & JOHNSON 9.66%

ABBVIE INC 6.94%

MERCK & COMPANY INC 5.04%

ROCHE HOLDING AG 4.74%

NOVARTIS AG 4.47%

ASTRAZENECA PLC 3.90%

NOVO NORDISK A/S 3.51%

Check overlap with more funds →

Window by window

Window by window: PBE vs PBPH: Holdings Overlap & Returns
	Total return
Window	PBE	PBPH
3 months	+14.2%	+16.2%
6 months	+27.1%	+25.6%
1 year	+44.2%	–
3 years	+90.4%	–
Since launchNot the same days: PBE Jun 2005 · PBPH Nov 2025	+650.5%	+27.0%

– means no data for this window. Open this comparison in the app →

Side by side

PBE Invesco Biotechnology & Genome ETF · Holds 32 stocks in biotech, 32% of its weight in S&P 500 companies PBPH Portfolio Building Block World Pharma and Biotech Index ETF · Holds 53 stocks in biotech, 59% of its weight in S&P 500 companies

Issuer Invesco Portfolio Building Block

Theme Biotech Biotech

In the S&P 500 32.3% 59.2%

Active share vs the S&P 500 99.0% 95.0%

In the Nasdaq-100 20.7% 13.6%

Holdings 32 53

Top ten, share of the fund 49.1% 61.9%

Expense ratio 0.59% 0.13%

Fee for the differing part 0.60% 0.14%

Total return, 1 year +44.2% +27.0% (since launch, Nov 25, 2025)

vs its benchmark not measured not measured

Below its high 0.0% 0.0%

Net assets, PBE as of Nov 3, 2026 and PBPH as of Jul 31, 2026 $442m $952m

As of Nov 4, 2026. Source: ETFIQ.

18% of the two portfolios are the same securities at the same weight.

Alert

About each fund

PBE

By weight, 32% of PBE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 49% of the fund across 32 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +44.2% with distributions reinvested.

PBPH

By weight, 59% of PBPH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 62% of the fund across 53 positions, as filed for Jul 31, 2026. Since it first traded on Nov 25, 2025 the fund returned +27.0% with distributions reinvested.

Questions people ask

Do PBE and PBPH hold the same stocks?: By their latest filings, 18% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, PBE or PBPH?: PBE has 32% of its weight in S&P 500 names and PBPH has 59%, so PBE differs more from the index.
Which is cheaper, PBE or PBPH?: PBE charges 0.59% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Other comparisons

PBE vs BBH PBE vs FBT PBE vs BBP PBE vs XBI PBPH vs BBH PBPH vs BBP PBPH vs FBT PBPH vs BBC

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →PBE on its own →PBPH on its own →PBE dividend history →PBE holdings →PBPH dividend history →PBPH holdings →Method →Standards and sources →

Sources and dates

PBE filings on SEC EDGAR ↗

PBE prospectus with the expense ratio (SEC) ↗

Invesco page for PBE ↗

PBPH filings on SEC EDGAR ↗

PBPH prospectus with the expense ratio (SEC) ↗

Portfolio Building Block page for PBPH ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, PBE against PBPH, data as of Nov 4, 2026. https://etfiq.com/compare/themes/pbe-vs-pbph

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Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.