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Data as of .

BBH vs PBPH: which is really different?

BBH and PBPH hold 18% of their weight in the same names.

VanEck Biotech ETF and Portfolio Building Block World Pharma and Biotech Index ETF.

60.4%BBH in the S&P 500
56.8%PBPH in the S&P 500
+40.5%BBH total return, 1 year
+13.3%PBPH total return, 1 year

ETFIQ Off-Index Score: BBH scores higher

How much of it is not the index it is sold as an alternative to?

BBH 61.7PBPH 32.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

BBH40% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
60%40%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 72% of the fund · 24 holdings filed Sep 17, 2026 · Nasdaq-100: 47% in60%40%in the S&P 500outsideactive share 99% · top ten 72% of the fund
PBPH43% of its weight is outside the S&P 500 · 6 months to Sep 18, 2026
57%43%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 95% · top ten 63% of the fund · 51 holdings filed Jan 31, 2026 · Nasdaq-100: 15% in57%43%in the S&P 500outsideactive share 95% · top ten 63% of the fund

18% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, BBH and PBPH hold 18% of their money in the same securities at the same weight.

Positions BBH and PBPH both hold, largest shared weight first
HoldingBBHPBPH
Amgen Inc15.03%4.33%
Gilead Sciences Inc13.81%4.10%
Argenx Se4.93%1.26%
Insmed Inc2.31%0.79%
Natera Inc4.97%0.71%
Biogen Inc2.71%0.62%
United Therapeutics Corp2.12%0.52%
Incyte Corp2.39%0.46%
Revolution Medicines Inc4.09%0.37%
Biomarin Pharmaceutical Inc1.25%0.24%
Only in each
Only in BBHOnly in PBPH
Vertex Pharmaceuticals Inc 8.32%ELI LILLY & CO 14.74%
Regeneron Pharmaceuticals Inc 7.00%JOHNSON & JOHNSON 9.10%
Moderna Inc 5.05%ABBVIE INC 6.53%
Iqvia Holdings Inc 4.61%ROCHE HOLDING AG-GENUSSCHEIN 5.28%
Illumina Inc 3.68%NOVARTIS AG-REG 4.99%
Guardant Health Inc 3.15%MERCK & CO. INC. 4.71%
Beone Medicines Ltd 2.75%ASTRAZENECA PLC 4.60%
Alnylam Pharmaceuticals Inc 2.73%NOVO NORDISK A/S-B 4.37%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jan 31, 2026 and Sep 18, 2026.

Performance, window by window

BBH and PBPH over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
BBHPBPHBBHPBPHBBHPBPH
3 months+24.8%+12.4%+22.5 pts+10.1 pts+27.3 pts+14.8 pts
6 months+29.0%+15.6%+11.0 pts−2.5 pts+4.8 pts−8.7 pts
1 year+40.5%not published+23.9 ptsnot published+18.7 ptsnot published
3 years+48.9%not published−29.5 ptsnot published−49.3 ptsnot published
Since launch+732.7%+13.3%−70.8 pts−0.8 pts−957.5 pts−5.7 pts
Open the live comparison on ETFIQ
BBH and PBPH on the same fields, as of Sep 18, 2026. Source: ETFIQ.
BBH
VanEck Biotech ETF
Holds 24 stocks in biotech, 60% of its weight in S&P 500 companies
PBPH
Portfolio Building Block World Pharma and Biotech Index ETF
Holds 51 stocks in biotech, 57% of its weight in S&P 500 companies
IssuerVanEckPortfolio Building Block
ThemeBiotechBiotech
In the S&P 50060.4%56.8%
Active share vs the S&P 50099.0%95.0%
In the Nasdaq-10047.2%14.7%
Holdings2451
Top ten, share of the fund72.4%62.7%
Expense ratio0.35%0.13%
Fee for the differing part0.35%0.14%
Total return, 1 year+40.5%+13.3% (since launch on Nov 25, 2025)
vs the S&P 500+23.9 pts−0.8 pts
vs the Nasdaq-100+18.7 pts−5.7 pts
Below its high−4.0%−4.8%
Net assets$470m$36m

BBH in plain words

By weight, 60% of BBH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 72% of the fund across 24 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +40.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 23.9 pts.

PBPH in plain words

By weight, 57% of PBPH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 63% of the fund across 51 positions, as filed for Jan 31, 2026. Since it launched on Nov 25, 2025 the fund returned +13.3% with distributions reinvested against +14.1% for the S&P 500, so a holder was behind by 0.8 pts.

Questions people ask

Do BBH and PBPH hold the same stocks?
By their latest filings, 18% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBH or PBPH?
BBH has 60% of its weight in S&P 500 names and PBPH has 57%, so BBH differs more from the index.
Which is cheaper, BBH or PBPH?
BBH charges 0.35% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

BBH against PBPH, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, BBH against PBPH, data as of Sep 18, 2026. https://etfiq.com/compare/themes/bbh-vs-pbph Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources