Data as of Nov 4, 2026.

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Thematic ETFs

FBT vs PBPH: Holdings Overlap & Returns

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FBT and PBPH hold 18% of their weight in the same names.

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Net assets: $3.1bn on Nov 3, 2026 for First Trust NYSE Arca Biotechnology Index Fund, and $952m on Jul 31, 2026 for Portfolio Building Block World Pharma and Biotech Index ETF.

At a glance
24.8%
FBT in the S&P 500
59.2%
PBPH in the S&P 500
+47.0%
FBT total return, 1 year
+27.0%
PBPH total return, since launch, Nov 25, 2025
FBT · 1 year to Nov 4, 2026 75% of its weight is outside the S&P 500
75% of its weight is outside the S&P 50025% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.25%75%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 38% of the fund · 30 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 17% in75% of its weight is outside the S&P 50025% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.25%75%inoutside the S&P 500active share 99% · Nasdaq-100: 17% in

25% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.

PBPH · 6 months to Nov 4, 2026 41% of its weight is outside the S&P 500
41% of its weight is outside the S&P 50059% of PBPH's weight is in S&P 500 companies and 41% is outside the index. Holdings as of Jul 31, 2026.59%41%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 95% · top ten 62% of the fund · 53 holdings as filed for Jul 31, 2026 · Nasdaq-100: 14% in41% of its weight is outside the S&P 50059% of PBPH's weight is in S&P 500 companies and 41% is outside the index. Holdings as of Jul 31, 2026.59%41%in the S&P 500outsideactive share 95% · Nasdaq-100: 14% in

59% of PBPH's weight is in S&P 500 companies and 41% is outside the index. Holdings as of Jul 31, 2026.

Pair scorecard

PBPH costs 0.42 points a year less.

FBT vs PBPH: Holdings Overlap & Returns
MeasureFBTPBPH
Return
Total return, 1 year+47.0%not published
Benchmark
What it tracksBiotechBiotech
Cost and size
Expense ratio0.55%0.13%
Net assets, FBT as of Nov 3, 2026 and PBPH as of Jul 31, 2026$3.1bn$952m
Holdings
Holdings in common18%

Method

What they share

18%

By the books each fund has filed, FBT and PBPH hold 18% of their money in the same securities at the same weight. Holdings dated Jul 31, 2026 and Nov 3, 2026.

0 half 100%

half

18% in common

Positions both hold · largest shared weight first FBT PBPH
Amgen Inc. 3.57% 4.63%
Gilead Sciences, Inc. 3.56% 3.77%
Vertex Pharmaceuticals Incorporated 3.34% 2.82%
Regeneron Pharmaceuticals, Inc. 4.18% 1.79%
argenx SE (ADR) 3.51% 1.24%
Natera, Inc. 3.11% 0.85%
Illumina, Inc. 2.75% 0.72%
Biogen Inc. 3.54% 0.70%
Alnylam Pharmaceuticals, Inc. 2.21% 0.63%
Incyte Corporation 3.35% 0.56%
United Therapeutics Corporation 3.51% 0.51%
Genmab A/S (ADR) 4.81% 0.40%
Only in one fund ↓
Only in FBT
Halozyme Therapeutics, Inc. 3.74%
Alkermes Plc 3.61%
Veracyte, Inc. 3.57%
TG Therapeutics, Inc. 3.52%
ADMA Biologics, Inc. 3.44%
NeoGenomics, Inc. 3.30%
Repligen Corporation 3.29%
Bio-Techne Corporation 3.22%
Only in PBPH
ELI LILLY & COMPANY 15.20%
JOHNSON & JOHNSON 9.66%
ABBVIE INC 6.94%
MERCK & COMPANY INC 5.04%
ROCHE HOLDING AG 4.74%
NOVARTIS AG 4.47%
ASTRAZENECA PLC 3.90%
NOVO NORDISK A/S 3.51%
Check overlap with more funds →

Window by window

Window by window: FBT vs PBPH: Holdings Overlap & Returns
Total return
WindowFBTPBPH
3 months+12.2%+16.2%
6 months+30.5%+25.6%
1 year+47.0%–
3 years+100.5%–
Since launchNot the same days: FBT Jun 2006 · PBPH Nov 2025+1,349.5%+27.0%

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Side by side

FBT First Trust NYSE Arca Biotechnology Index Fund · Holds 30 stocks in biotech, 25% of its weight in S&P 500 companies PBPH Portfolio Building Block World Pharma and Biotech Index ETF · Holds 53 stocks in biotech, 59% of its weight in S&P 500 companies
Theme Biotech Biotech
In the S&P 500 24.8% 59.2%
Active share vs the S&P 500 99.1% 95.0%
In the Nasdaq-100 16.9% 13.6%
Holdings 30 53
Top ten, share of the fund 38.2% 61.9%
Expense ratio 0.55% 0.13%
Fee for the differing part 0.55% 0.14%
Total return, 1 year +47.0% +27.0% (since launch, Nov 25, 2025)
vs its benchmark not measured not measured
Below its high −0.3% 0.0%
Net assets, FBT as of Nov 3, 2026 and PBPH as of Jul 31, 2026 $3.1bn $952m

As of Nov 4, 2026. Source: ETFIQ.

18% of the two portfolios are the same securities at the same weight.

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About each fund
FBT

By weight, 25% of FBT's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 38% of the fund across 30 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +47.0% with distributions reinvested.

PBPH

By weight, 59% of PBPH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 62% of the fund across 53 positions, as filed for Jul 31, 2026. Since it first traded on Nov 25, 2025 the fund returned +27.0% with distributions reinvested.

Questions people ask

Do FBT and PBPH hold the same stocks?
By their latest filings, 18% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FBT or PBPH?
FBT has 25% of its weight in S&P 500 names and PBPH has 59%, so FBT differs more from the index.
Which is cheaper, FBT or PBPH?
FBT charges 0.55% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.
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ETFIQ, FBT against PBPH, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fbt-vs-pbph

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