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Data as of .

BBP vs FBT: which is really different?

BBP and FBT hold 30% of their weight in the same names, and FBT returned more over the year.

Virtus Biotech ETF and First Trust NYSE Arca Biotechnology Index Fund.

12.4%BBP in the S&P 500
23.6%FBT in the S&P 500
+47.5%BBP total return, 1 year
+48.9%FBT total return, 1 year

ETFIQ Off-Index Score: FBT scores higher

How much of it is not the index it is sold as an alternative to?

BBP 61.7FBT 64.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

BBP88% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
12%88%inof its weight outside the S&P 500active share 99% · top ten 26% of the fund · 60 holdings filed Apr 30, 2026 · Nasdaq-100: 9% in12%88%inof its weight outside the S&P 500active share 99% · top ten 26% of the fund
FBT76% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
24%76%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 39% of the fund · 31 holdings filed Sep 18, 2026 · Nasdaq-100: 16% in24%76%inoutside the S&P 500active share 99% · top ten 39% of the fund

30% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, BBP and FBT hold 30% of their money in the same securities at the same weight.

Positions BBP and FBT both hold, largest shared weight first
HoldingBBPFBT
AXSOME THERAPEUTICS INC2.25%2.75%
UNITED THERAPEUTICS CORP1.85%2.80%
BIONTECH SE1.75%3.25%
AMGEN INC1.75%3.29%
EXELIXIS INC1.74%3.20%
BIOGEN INC1.74%3.35%
GILEAD SCIENCES INC1.74%3.58%
TG THERAPEUTICS INC1.73%3.08%
HALOZYME THERAPEUTICS INC1.64%4.57%
BIOMARIN PHARMACEUTICAL INC1.62%3.35%
INCYTE CORP1.60%3.33%
SAREPTA THERAPEUTICS INC1.55%3.29%
Only in each
Only in BBPOnly in FBT
IMMUNITYBIO INC 4.83%NeoGenomics, Inc. 4.37%
APELLIS PHARMACEUTICALS INC 2.60%Natera, Inc. 4.24%
KALVISTA PHARMACEUTICALS INC 2.53%Illumina, Inc. 3.90%
MODERNA INC 2.50%Repligen Corporation 3.80%
IOVANCE BIOTHERAPEUTICS INC 2.45%Corcept Therapeutics Inc. 3.72%
MIRUM PHARMACEUTICALS INC 2.40%Genmab A/S (ADR) 3.71%
KINIKSA PHARMACEUTICALS INTERNATIONAL PL 2.07%argenx SE (ADR) 3.50%
ROIVANT SCIENCES LTD 2.07%Bruker Corporation 3.17%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Sep 18, 2026.

Performance, window by window

BBP and FBT over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
BBPFBTBBPFBTBBPFBT
3 months+15.3%+17.2%+13.1 pts+14.9 pts+17.8 pts+19.6 pts
6 months+29.5%+40.6%+11.5 pts+22.6 pts+5.3 pts+16.4 pts
1 year+47.5%+48.9%+30.9 pts+32.3 pts+25.7 pts+27.1 pts
3 years+103.0%+80.7%+24.6 pts+2.3 pts+4.8 pts−17.5 pts
Since launch+304.4%+848.2%−56.6 pts+44.6 pts−371.1 pts−842.1 pts
Open the live comparison on ETFIQ
BBP and FBT on the same fields, as of Sep 18, 2026. Source: ETFIQ.
BBP
Virtus Biotech ETF
Holds 60 stocks in biotech, 12% of its weight in S&P 500 companies
FBT
First Trust NYSE Arca Biotechnology Index Fund
Holds 31 stocks in biotech, 24% of its weight in S&P 500 companies
IssuerVirtusFirst Trust
ThemeBiotechBiotech
In the S&P 50012.4%23.6%
Active share vs the S&P 50099.0%99.1%
In the Nasdaq-1008.9%16.2%
Holdings6031
Top ten, share of the fund25.7%39.2%
Expense ratio0.34%0.55%
Fee for the differing part0.34%0.55%
Total return, 1 year+47.5%+48.9%
vs the S&P 500+30.9 pts+32.3 pts
vs the Nasdaq-100+25.7 pts+27.1 pts
Below its high−5.5%−2.1%
Net assets$59m$2.9bn

BBP in plain words

By weight, 12% of BBP's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 26% of the fund across 60 positions, as filed for Apr 30, 2026. Over the year to Sep 18, 2026 the fund returned +47.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 30.9 pts. It sits 5.5% below its all-time high of Aug 19, 2026.

FBT in plain words

By weight, 24% of FBT's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 39% of the fund across 31 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +48.9% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 32.3 pts.

Questions people ask

Do BBP and FBT hold the same stocks?
By their latest filings, 30% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBP or FBT?
BBP has 12% of its weight in S&P 500 names and FBT has 24%, so FBT differs more from the index.
Which is cheaper, BBP or FBT?
BBP charges 0.34% a year and FBT charges 0.55%, so BBP is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

BBP against FBT, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, BBP against FBT, data as of Sep 18, 2026. https://etfiq.com/compare/themes/bbp-vs-fbt Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources