BBP vs IBB: which is really different?

BBP and IBB hold 33% of their weight in the same names, and BBP returned +45.2% over the year. Virtus Biotech ETF and iShares Biotechnology ETF.

BBP costs 0.10 points a year less; their one-year returns differ by 9.1 points; IBB is far larger, $10.8bn against $99m.

BBPIBB
Expense ratio0.34%0.44%
Net assets, BBP as of Jul 31, 2026 and IBB as of Oct 9, 2026$99m$10.8bn
Total return, 1 year+45.2%+36.1%
What it tracksBiotechBiotech
Holdings in common33%
S&P 500, total return, 1 year+17.3%
Against the S&P 500, 1 yearahead by 27.9 ptsahead by 18.8 pts

Holdings in common uses holdings dated Jul 31, 2026 and Oct 8, 2026.

10.5%
BBP in the S&P 500
39.5%
IBB in the S&P 500
+45.2%
BBP total return, 1 year
+36.1%
IBB total return, 1 year
BBP · 1 year to Oct 9, 202690% of its weight is outside the S&P 500
90% of its weight is outside the S&P 50011% of BBP's weight is in S&P 500 companies and 90% is outside the index. Holdings as of Jul 31, 2026.11%90%inof its weight outside the S&P 500active share 99% · top ten 20% of the fund · 67 holdings as filed for Jul 31, 2026 · Nasdaq-100: 9% in90% of its weight is outside the S&P 50011% of BBP's weight is in S&P 500 companies and 90% is outside the index. Holdings as of Jul 31, 2026.11%90%inof its weight outside the S&P 500active share 99% · Nasdaq-100: 9% in

11% of BBP's weight is in S&P 500 companies and 90% is outside the index. Holdings as of Jul 31, 2026.

IBB · 1 year to Oct 9, 202661% of its weight is outside the S&P 500
61% of its weight is outside the S&P 50040% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.40%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 50% of the fund · 245 holdings as published by its issuer for Oct 8, 2026 · Nasdaq-100: 33% in61% of its weight is outside the S&P 50040% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.40%61%in the S&P 500outside the S&P 500active share 99% · Nasdaq-100: 33% in

40% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.

ETFIQ Off-Index Score · BBP and IBB score the sameHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.3, the highest

A percentile among the 391 thematic ETFs with a holdings filing. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, BBP and IBB hold 33% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Jul 31, 2026 and Oct 8, 2026.

half

33% in common

Positions both hold, largest shared weight first
Holding BBP IBB
REGENERON PHARMACEUTICALS 1.72% 5.40%
BEONE MEDICINES LTD 1.65% 2.17%
INCYTE CORP 1.52% 1.67%
MODERNA INC 1.51% 5.30%
AMGEN INC 1.49% 7.89%
VERTEX PHARMACEUTICALS INC 1.48% 7.69%
GILEAD SCIENCES INC 1.43% 8.37%
BIOGEN INC 1.40% 2.36%
INSMED INC 1.39% 1.59%
ROIVANT SCIENCES LTD 1.55% 1.32%
UNITED THERAPEUTICS CORP 1.31% 1.63%
NEUROCRINE BIOSCIENCES INC 1.44% 1.05%
Only in BBP
CRINETICS PHARMACEUTICALS INC 3.34%
KINIKSA PHARMACEUTICALS INTERNATIONAL PLC 1.97%
VERASTEM INC 1.95%
OMEROS CORP 1.87%
XERIS BIOPHARMA HOLDINGS INC 1.64%
LIQUIDIA CORP 1.63%
LIGAND PHARMACEUTICALS 1.55%
TG THERAPEUTICS INC 1.45%
Only in IBB
NATERA 3.88%
ARGENX SE ADR 3.35%
ILLUMINA INC 2.94%
REVOLUTION MEDICINES 2.67%
GENMAB SPONSORED ADR 1.47%
CHARLES RIVER LABORATORIES INTERNA 1.04%
MEDPACE HOLDINGS 1.00%
BIO TECHNE 0.83%

33% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowBBPIBBBBPIBBBBPIBB
3 months+4.5%+7.5%+1.1 pts+4.1 pts+0.8 pts+3.9 pts
6 months+24.3%+21.9%+9.2 pts+6.8 pts+1.1 pts−1.3 pts
1 year+45.2%+36.1%+27.9 pts+18.8 pts+21.6 pts+12.5 pts
3 years+110.3%+69.1%+24.5 pts−16.7 pts+3.0 pts−38.2 pts
Since launch
BBP Dec 2014 · IBB Feb 2001
+308.1%+525.3%−63.1 pts−299.7 pts−400.3 pts−936.3 pts

Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

BBP
Virtus Biotech ETF · Holds 67 stocks in biotech, 10% of its weight in S&P 500 companies
IBB
iShares Biotechnology ETF · Holds 245 stocks in biotech, 40% of its weight in S&P 500 companies
Theme Biotech Biotech
In the S&P 500 10.5% 39.5%
Active share vs the S&P 500 99.0% 99.0%
In the Nasdaq-100 8.5% 33.1%
Holdings 67 245
Top ten, share of the fund 19.6% 49.9%
Expense ratio 0.34% 0.44%
Fee for the differing part 0.34% 0.44%
Total return, 1 year +45.2% +36.1%
vs the S&P 500 +27.9 pts +18.8 pts
vs the Nasdaq-100 +21.6 pts +12.5 pts
Below its high −4.7% −4.8%
Net assets, BBP as of Jul 31, 2026 and IBB as of Oct 9, 2026 $99m $10.8bn

As of Oct 9, 2026. Source: ETFIQ.

BBP in plain words

By weight, 10% of BBP's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 20% of the fund across 67 positions, as filed for Jul 31, 2026. Over the year to Oct 9, 2026 the fund returned +45.2% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 27.9 pts.

IBB in plain words

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +36.1% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 18.8 pts.

Questions people ask

Do BBP and IBB hold the same stocks?
By their latest filings, 33% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBP or IBB?
BBP has 10% of its weight in S&P 500 names and IBB has 40%, so BBP differs more from the index.
Which is cheaper, BBP or IBB?
BBP charges 0.34% a year and IBB charges 0.44%, so BBP is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from

ETFIQ links to the documents behind every figure; a link is not an endorsement. A comparison is not a recommendation.

How this is computed

It is a position in a set, not a rating, and neither end of it is a recommendation.

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

Every figure is an ETFIQ calculation with distributions reinvested.

Cite this page

ETFIQ, BBP against IBB, data as of Oct 9, 2026. https://etfiq.com/compare/themes/bbp-vs-ibb

Open data

Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms.