Data as of Nov 4, 2026.

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Thematic ETFs

FBT vs IBBQ: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, FBT returned +47.0% to IBBQ's +42.7%; 33% of their weight is in the same names.

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Net assets on Nov 3, 2026: $3.1bn for First Trust NYSE Arca Biotechnology Index Fund and $121m for Invesco Nasdaq Biotechnology ETF.

At a glance
24.8%
FBT in the S&P 500
42.5%
IBBQ in the S&P 500
+47.0%
FBT total return, 1 year
+42.7%
IBBQ total return, 1 year
FBT · 1 year to Nov 4, 2026 75% of its weight is outside the S&P 500
75% of its weight is outside the S&P 50025% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.25%75%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 38% of the fund · 30 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 17% in75% of its weight is outside the S&P 50025% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.25%75%inoutside the S&P 500active share 99% · Nasdaq-100: 17% in

25% of FBT's weight is in S&P 500 companies and 75% is outside the index. Holdings as of Nov 3, 2026.

IBBQ · 1 year to Nov 4, 2026 58% of its weight is outside the S&P 500
58% of its weight is outside the S&P 50043% of IBBQ's weight is in S&P 500 companies and 58% is outside the index. Holdings as of Nov 3, 2026.43%58%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 48% of the fund · 254 holdings as published by its issuer for Nov 3, 2026 · Nasdaq-100: 33% in58% of its weight is outside the S&P 50043% of IBBQ's weight is in S&P 500 companies and 58% is outside the index. Holdings as of Nov 3, 2026.43%58%in the S&P 500outside the S&P 500active share 99% · Nasdaq-100: 33% in

43% of IBBQ's weight is in S&P 500 companies and 58% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

IBBQ costs 0.36 points a year less; their one-year returns differ by 4.3 points; FBT is far larger, $3.1bn against $121m.

FBT vs IBBQ: Holdings Overlap & Returns
MeasureFBTIBBQ
Return
Total return, 1 year+47.0%+42.7%
Benchmark
What it tracksBiotechBiotech
Cost and size
Expense ratio0.55%0.19%
Net assets, as of Nov 3, 2026$3.1bn$121m
Holdings
Holdings in common33%

Method

Risk and return

Jun 18, 2021 to Oct 30, 2026 · 280 weekly returns
FBT IBBQ
Return
Total return edge FBT +64.4% +52.1%
Annualized edge FBT +9.7% +8.1%
Price return edge FBT +61.1% +44.3%
Risk
Volatility edge FBT (slight) 20.4% 21.2%
Max drawdown edge FBT −26.0% −35.4%
Risk-adjusted
Sharpe edge FBT 0.37 0.30
Sortino edge FBT 0.55 0.44
Calmar edge FBT 0.37 0.23
Reading

From Jun 2021 to Oct 2026, FBT returned more: +64.4% to +52.1%. FBT swung slightly less: 20.4% to 21.2%. FBT fell less at its worst: −26.0% to −35.4%.

Full scorecard

9 measures, with how each is measured
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Risk and return: FBT vs IBBQ: Holdings Overlap & Returns
MeasureFBTIBBQEdgeHow it is measured
Return
Total return+64.4%+52.1%FBTPrice change plus distributions, reinvested.
Annualized+9.7%+8.1%FBTTotal return as a yearly rate.
Price return+61.1%+44.3%FBTPrice change alone, distributions left out.
Risk
Volatility20.4%21.2%FBT (slight)Spread of weekly returns, annualized. Lower is steadier.
Downside deviation13.8%14.6%FBT (slight)Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown−26.0%−35.4%FBTDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.370.30FBTReturn above Treasury bills per unit of volatility.
Sortino0.550.44FBTReturn above Treasury bills per unit of downside deviation.
Calmar0.370.23FBTAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 280 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

33%

By the books each fund has filed, FBT and IBBQ hold 33% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026.

0 half 100%

half

33% in common

Positions both hold · largest shared weight first FBT IBBQ
Regeneron Pharmaceuticals, Inc. 4.18% 6.31%
Amgen Inc. 3.57% 8.42%
Gilead Sciences, Inc. 3.56% 8.97%
Vertex Pharmaceuticals Incorporated 3.34% 7.65%
Biogen Inc. 3.54% 2.36%
Illumina, Inc. 2.75% 2.31%
United Therapeutics Corporation 3.51% 1.66%
argenx SE (ADR) 3.51% 1.57%
Incyte Corporation 3.35% 1.53%
Alnylam Pharmaceuticals, Inc. 2.21% 1.37%
Exelixis, Inc. 3.88% 1.15%
Neurocrine Biosciences, Inc. 3.71% 1.07%
Only in one fund ↓
Only in FBT
TG Therapeutics, Inc. 3.52%
NeoGenomics, Inc. 3.30%
Repligen Corporation 3.29%
Bio-Techne Corporation 3.22%
Natera, Inc. 3.11%
Bruker Corporation 3.08%
Corcept Therapeutics Inc. 2.17%
Only in IBBQ
Moderna Inc 5.85%
Revolution Medicines Inc 2.67%
Royalty Pharma PLC 1.90%
Roivant Sciences Ltd 1.67%
Guardant Health Inc 1.51%
Insmed Inc 1.46%
Viatris Inc 1.39%
Medpace Holdings Inc 1.18%
Check overlap with more funds →

Window by window

Window by window: FBT vs IBBQ: Holdings Overlap & Returns
Total return
WindowFBTIBBQ
3 months+12.2%+12.7%
6 months+30.5%+23.7%
1 year+47.0%+42.7%
3 years+100.5%+96.2%
Since launchNot the same days: FBT Jun 2006 · IBBQ Jun 2021+1,349.5%+51.9%

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Side by side

FBT First Trust NYSE Arca Biotechnology Index Fund · Holds 30 stocks in biotech, 25% of its weight in S&P 500 companies IBBQ Invesco Nasdaq Biotechnology ETF · Holds 254 stocks in biotech, 42% of its weight in S&P 500 companies
Theme Biotech Biotech
In the S&P 500 24.8% 42.5%
Active share vs the S&P 500 99.1% 99.0%
In the Nasdaq-100 16.9% 32.7%
Holdings 30 254
Top ten, share of the fund 38.2% 48.1%
Expense ratio 0.55% 0.19%
Fee for the differing part 0.55% 0.19%
Total return, 1 year +47.0% +42.7%
vs its benchmark not measured not measured
Below its high −0.3% 0.0%
Net assets, as of Nov 3, 2026 $3.1bn $121m

As of Nov 4, 2026. Source: ETFIQ.

33% of the two portfolios are the same securities at the same weight.

Client brief:

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About each fund
FBT

By weight, 25% of FBT's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 38% of the fund across 30 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +47.0% with distributions reinvested.

IBBQ

By weight, 42% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 48% of the fund across 254 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +42.7% with distributions reinvested.

Questions people ask

Do FBT and IBBQ hold the same stocks?
By their latest filings, 33% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, FBT or IBBQ?
FBT has 25% of its weight in S&P 500 names and IBBQ has 42%, so FBT differs more from the index.
Which is cheaper, FBT or IBBQ?
FBT charges 0.55% a year and IBBQ charges 0.19%, so IBBQ is cheaper. Fees come from each fund's prospectus.
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ETFIQ, FBT against IBBQ, data as of Nov 4, 2026. https://etfiq.com/compare/themes/fbt-vs-ibbq

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