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Data as of .

IBBQ vs PBPH: which is really different?

IBBQ and PBPH hold 21% of their weight in the same names.

Invesco Nasdaq Biotechnology ETF and Portfolio Building Block World Pharma and Biotech Index ETF.

38.6%IBBQ in the S&P 500
56.8%PBPH in the S&P 500
+44.6%IBBQ total return, 1 year
+13.3%PBPH total return, 1 year

ETFIQ Off-Index Score: IBBQ scores higher

How much of it is not the index it is sold as an alternative to?

IBBQ 61.7PBPH 32.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

IBBQ61% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
39%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 45% of the fund · 256 holdings filed Sep 19, 2026 · Nasdaq-100: 33% in39%61%in the S&P 500outside the S&P 500active share 99% · top ten 45% of the fund
PBPH43% of its weight is outside the S&P 500 · 6 months to Sep 18, 2026
57%43%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 95% · top ten 63% of the fund · 51 holdings filed Jan 31, 2026 · Nasdaq-100: 15% in57%43%in the S&P 500outsideactive share 95% · top ten 63% of the fund

21% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, IBBQ and PBPH hold 21% of their money in the same securities at the same weight.

Positions IBBQ and PBPH both hold, largest shared weight first
HoldingIBBQPBPH
Amgen Inc8.05%4.33%
Gilead Sciences Inc7.89%4.10%
Argenx SE1.83%1.26%
Insmed Inc1.74%0.79%
Biogen Inc2.13%0.62%
United Therapeutics Corp1.41%0.52%
Incyte Corp1.68%0.46%
Revolution Medicines Inc2.72%0.37%
Viatris Inc1.32%0.35%
Ionis Pharmaceuticals Inc0.49%0.32%
Bridgebio Pharma Inc0.87%0.30%
BioMarin Pharmaceutical Inc0.83%0.24%
Only in each
Only in IBBQOnly in PBPH
Vertex Pharmaceuticals Inc 7.98%JOHNSON & JOHNSON 9.10%
Regeneron Pharmaceuticals Inc 5.42%ABBVIE INC 6.53%
Moderna Inc 4.10%ROCHE HOLDING AG-GENUSSCHEIN 5.28%
Illumina Inc 2.43%NOVARTIS AG-REG 4.99%
Alnylam Pharmaceuticals Inc 2.14%MERCK & CO. INC. 4.71%
Roivant Sciences Ltd 1.92%ASTRAZENECA PLC 4.60%
Royalty Pharma PLC 1.74%NOVO NORDISK A/S-B 4.37%
Guardant Health Inc 1.59%PFIZER INC 3.48%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Jan 31, 2026 and Sep 19, 2026.

Performance, window by window

IBBQ and PBPH over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
IBBQPBPHIBBQPBPHIBBQPBPH
3 months+15.8%+12.4%+13.6 pts+10.1 pts+18.3 pts+14.8 pts
6 months+24.9%+15.6%+6.9 pts−2.5 pts+0.7 pts−8.7 pts
1 year+44.6%not published+28.0 ptsnot published+22.8 ptsnot published
3 years+76.7%not published−1.7 ptsnot published−21.5 ptsnot published
Since launch+42.0%+13.3%−51.2 pts−0.8 pts−76.1 pts−5.7 pts
Open the live comparison on ETFIQ
IBBQ and PBPH on the same fields, as of Sep 18, 2026. Source: ETFIQ.
IBBQ
Invesco Nasdaq Biotechnology ETF
Holds 256 stocks in biotech, 39% of its weight in S&P 500 companies
PBPH
Portfolio Building Block World Pharma and Biotech Index ETF
Holds 51 stocks in biotech, 57% of its weight in S&P 500 companies
IssuerInvescoPortfolio Building Block
ThemeBiotechBiotech
In the S&P 50038.6%56.8%
Active share vs the S&P 50099.0%95.0%
In the Nasdaq-10033.2%14.7%
Holdings25651
Top ten, share of the fund44.8%62.7%
Expense ratio0.19%0.13%
Fee for the differing part0.19%0.14%
Total return, 1 year+44.6%+13.3% (since launch on Nov 25, 2025)
vs the S&P 500+28.0 pts−0.8 pts
vs the Nasdaq-100+22.8 pts−5.7 pts
Below its high−5.8%−4.8%
Net assets$96m$36m

IBBQ in plain words

By weight, 39% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 256 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +44.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 28.0 pts. It sits 5.8% below its all-time high of Aug 19, 2026.

PBPH in plain words

By weight, 57% of PBPH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 63% of the fund across 51 positions, as filed for Jan 31, 2026. Since it launched on Nov 25, 2025 the fund returned +13.3% with distributions reinvested against +14.1% for the S&P 500, so a holder was behind by 0.8 pts.

Questions people ask

Do IBBQ and PBPH hold the same stocks?
By their latest filings, 21% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, IBBQ or PBPH?
IBBQ has 39% of its weight in S&P 500 names and PBPH has 57%, so IBBQ differs more from the index.
Which is cheaper, IBBQ or PBPH?
IBBQ charges 0.19% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

IBBQ against PBPH, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, IBBQ against PBPH, data as of Sep 18, 2026. https://etfiq.com/compare/themes/ibbq-vs-pbph Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources