Data as of .
IBBQ vs PBE: which is really different?
IBBQ and PBE hold 38% of their weight in the same names, and IBBQ returned more over the year.
ETFIQ Off-Index Score: IBBQ scores higher
How much of it is not the index it is sold as an alternative to?
A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed
38% of the two portfolios are the same securities at the same weight.
What they hold in common
By the books each fund has filed, IBBQ and PBE hold 38% of their money in the same securities at the same weight.
| Holding | IBBQ | PBE |
|---|---|---|
| Gilead Sciences Inc | 7.89% | 5.27% |
| Regeneron Pharmaceuticals Inc | 5.42% | 4.89% |
| Vertex Pharmaceuticals Inc | 7.98% | 4.77% |
| Amgen Inc | 8.05% | 4.53% |
| Moderna Inc | 4.10% | 2.75% |
| Illumina Inc | 2.43% | 5.53% |
| Biogen Inc | 2.13% | 5.07% |
| Royalty Pharma PLC | 1.74% | 4.88% |
| Incyte Corp | 1.68% | 2.73% |
| United Therapeutics Corp | 1.41% | 2.70% |
| Neurocrine Biosciences Inc | 0.98% | 2.70% |
| Exelixis Inc | 0.98% | 2.91% |
| Only in IBBQ | Only in PBE |
|---|---|
| Revolution Medicines Inc 2.72% | Natera Inc 5.70% |
| Alnylam Pharmaceuticals Inc 2.14% | TG Therapeutics Inc 2.91% |
| Roivant Sciences Ltd 1.92% | QIAGEN NV 2.81% |
| Argenx SE 1.83% | Repligen Corp 2.76% |
| Insmed Inc 1.74% | |
| Guardant Health Inc 1.59% | |
| Viatris Inc 1.32% | |
| Medpace Holdings Inc 1.17% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 19, 2026.
Performance, window by window
| Window | Total return | vs the S&P 500 | vs the Nasdaq-100 | |||
|---|---|---|---|---|---|---|
| IBBQ | PBE | IBBQ | PBE | IBBQ | PBE | |
| 3 months | +15.8% | +13.2% | +13.6 pts | +11.0 pts | +18.3 pts | +15.7 pts |
| 6 months | +24.9% | +25.9% | +6.9 pts | +7.8 pts | +0.7 pts | +1.6 pts |
| 1 year | +44.6% | +36.2% | +28.0 pts | +19.6 pts | +22.8 pts | +14.4 pts |
| 3 years | +76.7% | +65.0% | −1.7 pts | −13.4 pts | −21.5 pts | −33.1 pts |
| Since launch | +42.0% | +492.4% | −51.2 pts | −311.1 pts | −76.1 pts | −1197.8 pts |
| IBBQ Invesco Nasdaq Biotechnology ETF Holds 256 stocks in biotech, 39% of its weight in S&P 500 companies | PBE Invesco Biotechnology & Genome ETF Holds 33 stocks in biotech, 30% of its weight in S&P 500 companies | |
|---|---|---|
| Issuer | Invesco | Invesco |
| Theme | Biotech | Biotech |
| In the S&P 500 | 38.6% | 30.0% |
| Active share vs the S&P 500 | 99.0% | 99.0% |
| In the Nasdaq-100 | 33.2% | 19.5% |
| Holdings | 256 | 33 |
| Top ten, share of the fund | 44.8% | 46.7% |
| Expense ratio | 0.19% | 0.59% |
| Fee for the differing part | 0.19% | 0.60% |
| Total return, 1 year | +44.6% | +36.2% |
| vs the S&P 500 | +28.0 pts | +19.6 pts |
| vs the Nasdaq-100 | +22.8 pts | +14.4 pts |
| Below its high | −5.8% | −3.9% |
| Net assets | $96m | $414m |
IBBQ in plain words
By weight, 39% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 256 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +44.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 28.0 pts. It sits 5.8% below its all-time high of Aug 19, 2026.
PBE in plain words
By weight, 30% of PBE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 47% of the fund across 33 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +36.2% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 19.6 pts.
Questions people ask
- Do IBBQ and PBE hold the same stocks?
- By their latest filings, 38% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
- Which is more different from the S&P 500, IBBQ or PBE?
- IBBQ has 39% of its weight in S&P 500 names and PBE has 30%, so IBBQ differs more from the index.
- Which is cheaper, IBBQ or PBE?
- IBBQ charges 0.19% a year and PBE charges 0.59%, so IBBQ is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, IBBQ against PBE, data as of Sep 18, 2026. https://etfiq.com/compare/themes/ibbq-vs-pbe Free to use with attribution; the underlying files are at Open data.