Do IBBQ and PBE hold the same stocks?

By their latest filings, 40% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, IBBQ or PBE?

IBBQ has 42% of its weight in S&P 500 names and PBE has 32%, so IBBQ differs more from the index.

Which is cheaper, IBBQ or PBE?

IBBQ charges 0.19% a year and PBE charges 0.59%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

IBBQ vs PBE: Holdings Overlap & Returns

Share on X Download as PDF

Over the year to Nov 4, 2026, IBBQ returned +42.7% to PBE's +44.2%; 40% of their weight is in the same names.

askIQ about this page

askIQ about IBBQ and PBE

Net assets on Nov 3, 2026: $121m for Invesco Nasdaq Biotechnology ETF and $442m for Invesco Biotechnology & Genome ETF.

IBBQ on its own →PBE on its own →

At a glance

42.5%

IBBQ in the S&P 500

32.3%

PBE in the S&P 500

+42.7%

IBBQ total return, 1 year

+44.2%

PBE total return, 1 year

IBBQ · 1 year to Nov 4, 2026 58% of its weight is outside the S&P 500

43% of IBBQ's weight is in S&P 500 companies and 58% is outside the index. Holdings as of Nov 3, 2026.

PBE · 1 year to Nov 4, 2026 68% of its weight is outside the S&P 500

32% of PBE's weight is in S&P 500 companies and 68% is outside the index. Holdings as of Nov 3, 2026.

Pair scorecard

IBBQ costs 0.40 points a year less; their one-year returns differ by 1.5 points; PBE is 3.7 times larger.

IBBQ vs PBE: Holdings Overlap & Returns
Measure	IBBQ	PBE
Return
Measure	IBBQ	PBE
Total return, 1 year	+42.7%	+44.2%
Benchmark
Measure	IBBQ	PBE
What it tracks	Biotech	Biotech
Cost and size
Measure	IBBQ	PBE
Expense ratio	0.19%	0.59%
Net assets, as of Nov 3, 2026	$121m	$442m
Holdings
Measure	IBBQ	PBE
Holdings in common	40%

Method

Risk and return

Jun 18, 2021 to Oct 30, 2026 · 280 weekly returns

IBBQ PBE

Return

Total return edge IBBQ +52.1% +37.0%

Annualized edge IBBQ +8.1% +6.0%

Price return edge IBBQ +44.3% +34.0%

Risk

Volatility edge Tie 21.2% 21.3%

Max drawdown edge PBE (slight) −35.4% −33.5%

Risk-adjusted

Sharpe edge IBBQ 0.30 0.21

Sortino edge IBBQ 0.44 0.30

Calmar edge IBBQ 0.23 0.18

Reading

From Jun 2021 to Oct 2026, IBBQ returned more: +52.1% to +37.0%. IBBQ and PBE swung about the same: 21.2% and 21.3%. PBE fell slightly less at its worst: −33.5% to −35.4%.

Full scorecard

9 measures, with how each is measured Open ↓

Risk and return: IBBQ vs PBE: Holdings Overlap & Returns
Measure	IBBQ	PBE	Edge	How it is measured
Return
Total return	+52.1%	+37.0%	IBBQ	Price change plus distributions, reinvested.
Annualized	+8.1%	+6.0%	IBBQ	Total return as a yearly rate.
Price return	+44.3%	+34.0%	IBBQ	Price change alone, distributions left out.
Risk
Volatility	21.2%	21.3%	Tie	Spread of weekly returns, annualized. Lower is steadier.
Downside deviation	14.6%	14.7%	Tie	Like volatility, counting only weeks below the Treasury bill rate.
Max drawdown	−35.4%	−33.5%	PBE (slight)	Deepest fall from a high to the low after it.
Risk-adjusted
Sharpe	0.30	0.21	IBBQ	Return above Treasury bills per unit of volatility.
Sortino	0.44	0.30	IBBQ	Return above Treasury bills per unit of downside deviation.
Calmar	0.23	0.18	IBBQ	Annualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 280 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

40%

By the books each fund has filed, IBBQ and PBE hold 40% of their money in the same securities at the same weight. Holdings dated Nov 3, 2026.

50%

0 half 100%

half

40% in common

Positions both hold · largest shared weight first IBBQ PBE

Regeneron Pharmaceuticals Inc 6.31% 5.62%

Gilead Sciences Inc 8.97% 5.42%

Amgen Inc 8.42% 5.02%

Vertex Pharmaceuticals Inc 7.65% 4.62%

Moderna Inc 5.85% 3.78%

Biogen Inc 2.36% 5.43%

Illumina Inc 2.31% 5.10%

Royalty Pharma PLC 1.90% 5.15%

United Therapeutics Corp 1.66% 3.05%

Incyte Corp 1.53% 2.38%

Exelixis Inc 1.15% 3.35%

Neurocrine Biosciences Inc 1.07% 2.82%

Only in one fund ↓

Only in IBBQ

Revolution Medicines Inc 2.67%

Roivant Sciences Ltd 1.67%

Argenx SE 1.57%

Guardant Health Inc 1.51%

Insmed Inc 1.46%

Viatris Inc 1.39%

Alnylam Pharmaceuticals Inc 1.37%

Medpace Holdings Inc 1.18%

Only in PBE

Natera Inc 5.56%

QIAGEN NV 3.03%

TG Therapeutics Inc 2.88%

Repligen Corp 2.58%

Check overlap with more funds →

Window by window

Window by window: IBBQ vs PBE: Holdings Overlap & Returns
	Total return
Window	IBBQ	PBE
3 months	+12.7%	+14.2%
6 months	+23.7%	+27.1%
1 year	+42.7%	+44.2%
3 years	+96.2%	+90.4%
Since launchNot the same days: IBBQ Jun 2021 · PBE Jun 2005	+51.9%	+650.5%

Open this comparison in the app →

Side by side

IBBQ Invesco Nasdaq Biotechnology ETF · Holds 254 stocks in biotech, 42% of its weight in S&P 500 companies PBE Invesco Biotechnology & Genome ETF · Holds 32 stocks in biotech, 32% of its weight in S&P 500 companies

Issuer Invesco Invesco

Theme Biotech Biotech

In the S&P 500 42.5% 32.3%

Active share vs the S&P 500 99.0% 99.0%

In the Nasdaq-100 32.7% 20.7%

Holdings 254 32

Top ten, share of the fund 48.1% 49.1%

Expense ratio 0.19% 0.59%

Fee for the differing part 0.19% 0.60%

Total return, 1 year +42.7% +44.2%

vs its benchmark not measured not measured

Below its high 0.0% 0.0%

Net assets, as of Nov 3, 2026 $121m $442m

As of Nov 4, 2026. Source: ETFIQ.

40% of the two portfolios are the same securities at the same weight.

Client brief:

The two-page PDF for this pair is coming. Save the comparison to follow its changes. Free. It needs an email sign-in, once.

Your saved page · Privacy.

Alert

About each fund

IBBQ

By weight, 42% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 48% of the fund across 254 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +42.7% with distributions reinvested.

PBE

By weight, 32% of PBE's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 49% of the fund across 32 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +44.2% with distributions reinvested.

Questions people ask

Do IBBQ and PBE hold the same stocks?: By their latest filings, 40% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, IBBQ or PBE?: IBBQ has 42% of its weight in S&P 500 names and PBE has 32%, so IBBQ differs more from the index.
Which is cheaper, IBBQ or PBE?: IBBQ charges 0.19% a year and PBE charges 0.59%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Other comparisons

IBBQ vs BBH IBBQ vs BBP IBBQ vs BBC IBBQ vs XBI PBE vs BBC PBE vs BBP PBE vs BBH PBE vs XBI

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →IBBQ on its own →PBE on its own →IBBQ dividend history →IBBQ holdings →PBE dividend history →PBE holdings →Method →Standards and sources →

Sources and dates

IBBQ filings on SEC EDGAR ↗

IBBQ prospectus with the expense ratio (SEC) ↗

Invesco page for IBBQ ↗

PBE filings on SEC EDGAR ↗

PBE prospectus with the expense ratio (SEC) ↗

Invesco page for PBE ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, IBBQ against PBE, data as of Nov 4, 2026. https://etfiq.com/compare/themes/ibbq-vs-pbe

Open data →

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.