GNOM Global X Genomics & Biotechnology ETF

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$71.51
+3.9% · 1 day, price
IQ’s readingComputed nightly from ETFIQ data. Not written live.

Between May 29, 2026 and Oct 16, 2026, GNOM returned 29.6%, against 27.8% for its own holdings.

Holds 50 stocks in genomics and gene editing, 18% of its weight in S&P 500 companiesGlobal X ↗Expense ratio 0.50%Fund assets $104m on Oct 12, 2026First traded Apr 10, 2019Benchmark Its own holdings, as of May 31, 2026; no other fund tracks the Solactive Genomics Index, the index its prospectus namesFund page at the issuer ↗SEC filings ↗Every Global X fund ETFIQ coversDividend history

Promise check: Not measuredIts theme exposure is measured once ETFIQ defines its theme company by company.

GNOM risk and return scorecard

vs its own holdings

Not measured: its benchmark is its own holdings, which has no weekly price series.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records; risk-free rate: U.S. Treasury, Daily Treasury Bill Rates, 13-week coupon equivalent Method · Data

Money in and out

Net fund flows · Oct 12, 2026
12 months to May 31, 2026
−$8.1m
3 years to May 31, 2026
−$129m
5 years to May 31, 2026
−$499k

What you earned

GNOM +1.7%: total return over one month to Oct 28, 2026.
GNOM+1.7%
GNOM +33.1%: total return over three months to Oct 28, 2026.
GNOM+33.1%
GNOM +62.9%: total return over six months to Oct 28, 2026.
GNOM+62.9%
GNOM +57.5%: total return over the year to Oct 28, 2026.
GNOM+57.5%
GNOM +63.5%: total return over one year to Oct 28, 2026.
GNOM+63.5%
GNOM +106.9%: total return over three years to Oct 28, 2026.
GNOM+106.9%
GNOM −15.3%: total return over five years to Oct 28, 2026.
GNOM−15.3%
GNOM +18.2%: total return since launch to Oct 28, 2026.
GNOM+18.2%

What did you actually buy?

Genomics and gene editing · holdings as of May 31, 2026
17.9%
Already in the S&P 500
97.6%
Active share vs the S&P 500
42.5%
Top ten holdings
+63.5%
Total return, 1 year
1.5%
12-month yield, capital gains included, on its starting price
$0.0579
Last payment (paid annually), ex-date Jun 29, 2026
Share already in the S&P 500
17.9% of the fund by weight, holdings as of May 31, 2026.
Ten largest holdings
GUARDANT HEALTH, INC.5.6%
ILLUMINA, INC.4.8%
NATERA, INC.4.2%
BIOMARIN PHARMACEUTICAL INC.4.1%
ARROWHEAD PHARMACEUTICALS, INC.4.1%
Legend Biotech Corp4.0%
Praxis Precision Medicines Inc4.0%
Twist Bioscience Corp4.0%
VERTEX PHARMACEUTICALS INCORPORATED4.0%
CRISPR Therapeutics AG3.9%

More on GNOM

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Price, 1 year

$71.51+3.9%1 day, priceClose, Oct 28, 2026

Price only. Total return over the same days, distributions reinvested, was +63.5%. Computed by ETFIQ from Tiingo daily prices.

Source: Tiingo end-of-day prices. Data as of Oct 28, 2026. Updated every trading night. Report a data error

Points (pts) are percentage points.

GNOM returns by window: total return, cash paid and price change
WindowTotal returnS&P 500 (SPY)
1M Sep 28 – Oct 28, 2026+1.7%+0.9%
3M Jul 29 – Oct 28, 2026+33.1%+6.1%
6M Apr 29 – Oct 28, 2026+62.9%+9.1%
YTD Dec 31, 2025 – Oct 28, 2026+57.5%+14.1%
1Y Oct 28, 2025 – Oct 28, 2026+63.5%+13.6%
3Y Oct 27, 2023 – Oct 28, 2026+106.9%+95.0%
5Y Oct 29, 2021 – Oct 28, 2026−15.3%+79.8%
Since launch Apr 10, 2019 – Oct 28, 2026+18.2%+199.1%
Since launch, annualised Apr 10, 2019 – Oct 28, 2026+2.2%–

Total returns, distributions reinvested.

Source: Tiingo end-of-day prices, with distributions reinvested.

Money in and out

Monthly data · as of Oct 12, 2026

GNOM: in the month to Oct 31, 2026, net $5.4m came in.

12 months
−$8.1m
−19.8% of $41.0m on May 31, 2025
Jun 1, 2025 to May 31, 2026
monthly, from SEC filings
3 years
−$129m
−66.1% of $195m on May 31, 2023
Jun 1, 2023 to May 31, 2026
monthly, from SEC filings
5 years
−$499k
−0.3% of $201m on May 31, 2021
Jun 1, 2021 to May 31, 2026
monthly, from SEC filings
Sep 2019 to May 2026
+$184m
Sep 1, 2019 to May 31, 2026
monthly, from SEC filings

Computed by ETFIQ from the monthly sales and redemptions GNOM files with the SEC on Form N-PORT.

How this is computed

ETFIQ reads no daily data for this fund, so its flows are monthly, and the latest month filed is Oct 2026. Every day and month ETFIQ holds for GNOM, back to Sep 2019, is in its flows file. Flows across every fund · How these flows are computed · Compare GNOM with other funds in the flows tool

Month by month, money in and money outJul 2023 to Oct 2026

GNOM, money in and money out each month from Jul 2023 to May 2026: two bars a month, money in above the line and money out below. Every bar is from GNOM’s SEC filings (N-PORT item B.6). Oct 2026 is still in progress, so it is in the list and not drawn. Of the 36 months listed, money came in on net in 8 and went out in 18.

Every bar is from GNOM’s SEC filings (N-PORT item B.6). Of the 36 months listed, money came in on net in 8 and went out in 18.

MonthInOutNet
Oct 2026 ETFIQ, the sum of its days, Oct 7 to Oct 12+$5.4m$0+$5.4m
May 2026 SEC Form N-PORT+$6.6m−$6.5m+$52k
Apr 2026 SEC Form N-PORT$0$0$0
Mar 2026 SEC Form N-PORT+$2.1m−$828k+$1.3m
Feb 2026 SEC Form N-PORT$0$0$0
Jan 2026 SEC Form N-PORT$0−$1.9m−$1.9m
Dec 2025 SEC Form N-PORT$0−$1.9m−$1.9m
Nov 2025 SEC Form N-PORT$0−$2.1m−$2.1m
Oct 2025 SEC Form N-PORT$0$0$0
Sep 2025 SEC Form N-PORT+$661−$1.2m−$1.2m
Aug 2025 SEC Form N-PORT$0$0$0
Jul 2025 SEC Form N-PORT$0−$2.4m−$2.4m
Jun 2025 SEC Form N-PORT+$84k$0+$84k
May 2025 SEC Form N-PORT$0−$3.7m−$3.7m
Apr 2025 SEC Form N-PORT−$153k−$5.2m−$5.3m
Mar 2025 SEC Form N-PORT$0−$2.7m−$2.7m
Feb 2025 SEC Form N-PORT$0−$2.7m−$2.7m
Jan 2025 SEC Form N-PORT$0$0$0
Dec 2024 SEC Form N-PORT$0−$3.5m−$3.5m
Nov 2024 SEC Form N-PORT$0$0$0
Oct 2024 SEC Form N-PORT$0−$1.6m−$1.6m
Sep 2024 SEC Form N-PORT+$219k$0+$219k
Aug 2024 SEC Form N-PORT$0$0$0
Jul 2024 SEC Form N-PORT+$450k−$18.9m−$18.5m
Jun 2024 SEC Form N-PORT−$22.6m$0−$22.6m
May 2024 SEC Form N-PORT$0$0$0
Apr 2024 SEC Form N-PORT$0$0$0
Mar 2024 SEC Form N-PORT+$11.7m−$1.1m+$10.6m
Feb 2024 SEC Form N-PORT$0$0$0
Jan 2024 SEC Form N-PORT$0−$2.9m−$2.9m
Dec 2023 SEC Form N-PORT$0−$5.1m−$5.1m
Nov 2023 SEC Form N-PORT$0−$2.3m−$2.3m
Oct 2023 SEC Form N-PORT+$793k−$75.0m−$74.2m
Sep 2023 SEC Form N-PORT+$50.0m−$3.3m+$46.7m
Aug 2023 SEC Form N-PORT+$1.5m−$40.9m−$39.4m
Jul 2023 SEC Form N-PORT+$6.0m$0+$6.0m

Most recent first.

How this is computed

N-PORT months: money in is sales plus reinvestments; money out is redemptions. Months summed from daily data: money in adds the days money came in; money out adds the days it went out.

N-PORT months are the filed sales plus reinvestments less redemptions. Later months add up the daily data; the Source column names any missing day.

Source: ETFIQ, from the fund’s SEC N-PORT filings. Data as of Oct 12, 2026. Updated when the fund files its next report.

GNOM key stats

52-week high, daily closes to Oct 28, 2026 (ETFIQ)$72.30 on Oct 5, 2026
52-week low, daily closes to Oct 28, 2026 (ETFIQ)$41.40 on Mar 30, 2026
Close on Oct 28, 2026, within that range (ETFIQ)$71.51, 97% of the way from the low to the high
Holdings50
Top ten holdings weight42.5%
Range, beta and R-squared computed by ETFIQ from Tiingo daily prices.

Trading

as of Oct 28, 2026
Trading · GNOMas of Oct 28, 2026
·
Not scored2 of 6 measured · Oct 28, 2026
0 · Hard to tradeIQ Liquidity Score100 · Trades like a giant
Cost for your order · one way, half its 30-day median spread
$1,000$2.550.26%
$10,000$260.26%
Premium or discount to NAV, Oct 12 close−0.10%
−0.6%95% of days within ±0.42% · the 1% band is off this scale+0.6%
How to tradeLimit: midpoint + 17¢ to buy, midpoint − 17¢ to sell.At the Oct 12 close of $66.64, that’s $66.81 to buy and $66.47 to sell.
Full trading page: components, premium history, dealers →

GNOM top ten by weight, 42.5% of the fund, of its 50 equity positions, from the holdings filed for May 31, 2026. That is 150 days before Oct 28, 2026, older than the issuer’s daily file, which ETFIQ could not read. Source: the fund’s SEC filing.

Source: Holdings filing (SEC Form N-PORT). Data as of May 31, 2026.

About GNOM

Theme (ETFIQ, editorial)Genomics and gene editing
First tradedApr 10, 2019
Already in the S&P 500, by weight (ETFIQ)17.9%
Outside the S&P 500, by weight (ETFIQ)82%
Active share vs the S&P 500 (ETFIQ)97.6%
Already in the Nasdaq-100, by weight (ETFIQ)5.9%
Active share vs the Nasdaq-100 (ETFIQ)98.8%
Top ten holdings weight42.5%
Holdings50
Holdings as of (SEC N-PORT)May 31, 2026
Top holdingsGUARDANT HEALTH, INC. 5.6%, ILLUMINA, INC. 4.8%, NATERA, INC. 4.2%, BIOMARIN PHARMACEUTICAL INC. 4.1%, ARROWHEAD PHARMACEUTICALS, INC. 4.1%, Legend Biotech Corp 4.0%, Praxis Precision Medicines Inc 4.0%, Twist Bioscience Corp 4.0%, VERTEX PHARMACEUTICALS INCORPORATED 4.0%, CRISPR Therapeutics AG 3.9%
Net assets (issuer page, as of Oct 12, 2026)$104mReport
Benchmark (ETFIQ, from its filings)Its own holdings, as of May 31, 2026; no other fund tracks the Solactive Genomics Index, the index its prospectus names
GNOM, May 29, 2026 to Oct 16, 2026+29.57%
Its book of May 29, 2026, the same days (ETFIQ, measured on 98% of the book by weight)+27.84%
Against its own holdings (ETFIQ)+1.73 pts
Below its all-time high (ETFIQ)−34.9%
Expense ratio (485BPOS XBRL, Mar 27, 2026)0.50%Report
Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ)0.51%
Closest funds by holdings overlapGNMX 41%, ARKG 40%, WDNA 31%, PBE 31%, HLTH 31%
Below its all-time high34.9%, high on Feb 8, 2021
How we measure
The top ten holdings are 42% of the fund across 50 positions, as filed for May 31, 2026. Over the year to Oct 28, 2026 the fund returned +63.5% with distributions reinvested. It sits 34.9% below its all-time high of Feb 8, 2021.
Holdings from the fund’s latest public SEC N-PORT filing; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. Method
IQ Investment Committee on GNOM

12 seats on GNOM, as of Oct 28, 2026: 1 Supports, 1 Mixed, 5 Challenges, 5 Not enough data.

In the tradition ofJohn BogleBogle-style Low CostChallenges
In the tradition ofBenjamin GrahamGraham-style Margin of SafetyNot enough data
In the tradition ofWarren Buffett & Charlie MungerBuffett & Munger-style QualityNot enough data
In the tradition ofPeter LynchLynch-style Growth at a Reasonable PriceNot enough data
In the tradition ofJohn TempletonTempleton-style Global ContrarianNot enough data
In the tradition ofRay DalioDalio-style All-WeatherChallenges
In the tradition ofHoward MarksMarks-style Cycles & RiskChallenges
In the tradition ofStanley DruckenmillerDruckenmiller-style Macro & LiquidityChallenges
In the tradition ofDavid SwensenSwensen-style DiversificationChallenges
In the tradition ofCathie WoodWood-style Disruptive InnovationNot enough data
In the tradition ofJesse LivermoreLivermore-style Trend FollowingSupports
Uses ETFIQ’s measuresThe ETFIQ SkepticETFIQ’s own seatMixed
Put GNOM to the committee →See all seats →No investor named is affiliated with or endorses ETFIQ. Not investment advice.

Questions people ask about GNOM

How much of GNOM is in S&P 500 companies?
By its holdings filed for May 31, 2026, 18% of GNOM by weight is stocks the S&P 500 already holds. Its active share against the index is 98%, so that share is the part doing something different.
What does GNOM hold?
50 positions as filed for May 31, 2026, with the top ten at 42% of the fund. The largest are GUARDANT HEALTH, INC. at 5.6%, ILLUMINA, INC. at 4.8%, NATERA, INC. at 4.2%.
Has GNOM beaten the S&P 500?
Over the year to Oct 28, 2026 GNOM returned +63.5% with distributions reinvested, against +13.6% for the S&P 500, so it finished ahead of the index by 49.9 points.
What does GNOM cost?
The prospectus expense ratio is 0.50% a year. Because 98% of the fund differs from the S&P 500, the fee on that differing part works out at 0.51%.
Sources and dates
Prices, GNOM and S&P 500 (SPY)Tiingo end-of-day · Oct 28, 2026
Net assets, $104mIssuer page · Oct 12, 2026

Links are sources, not endorsements.

Cite this pageCitation, APA and Markdown

ETFIQ, GNOM, thematic ETFs, data as of Oct 28, 2026. https://etfiq.com/funds/gnom

The difference bar for GNOM, redrawn every trading night.

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms. The underlying files are at Open data.

How differently the money is placed, counting weights: one minus the sum of the smaller weight of each security across the fund and the index. 100% means nothing in common; 0% means the index itself. Two funds can hold the same names and still have a high active share if they weight them very differently.
Weight overlap
The share of money two portfolios hold in the same securities at the same weight.
Already in the index
The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at different weights.
The weight of the ten largest holdings. Above 50% the fund is a bet on a handful of companies, whatever the theme.
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GNOM: 18% of GNOM's weight is in S&P 500 companies and 82% is outside the index. Holdings as of May 31, 2026.
<figure style="margin:0;max-width:640px">
<a href="https://etfiq.com/funds/gnom"><img src="https://etfiq.com/assistant/api/embed/themes/gnom.svg" alt="GNOM: 18% of GNOM&#x27;s weight is in S&amp;P 500 companies and 82% is outside the index. Holdings as of May 31, 2026." width="640" style="max-width:100%;height:auto"></a>
<figcaption style="font:13px/1.5 sans-serif">GNOM: 18% of GNOM&#x27;s weight is in S&amp;P 500 companies and 82% is outside the index. Holdings as of May 31, 2026. Data: <a href="https://etfiq.com/funds/gnom">ETFIQ</a></figcaption>
</figure>

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Snapshot, Oct 28, 2026. More on the tabs above.