ARKG ARK Genomic Revolution ETF
Holds 33 stocks in biotech and genomics, 4% of its weight in S&P 500 companies
ARKG holds 33 stocks, and 96% of its weight is outside the S&P 500.
Key facts
ETFIQ Off-Index Score
56.3joint 162nd of 371
ARKG shares 1 of its 33 holdings with the S&P 500. Only 1.5% of its weight overlaps the index.
How much of it is not the index it is sold as an alternative to?
That is the share of the 371 thematic ETFs with a holdings filing sitting at or below ARKG. A position in this set, not a rating: it moves when the set moves, and it is not a figure to average against another desk's.
2nd of 11 biotech and genomics ETFs by net assets 2nd of 11 biotech and genomics ETFs by least weight in the S&P 500
Its ten largest equity positions
| Holding | Ticker | Weight | |
|---|---|---|---|
| 10X GENOMICS INC-CLASS A | TXG | 10.26% | |
| TWIST BIOSCIENCE CORP | TWST | 8.33% | |
| TEMPUS AI INC-CL A | TEM | 7.67% | |
| CRISPR THERAPEUTICS AG | CRSP | 5.92% | |
| PERSONALIS INC | PSNL | 5.86% | |
| ABSCI CORP | ABSI | 4.63% | |
| GUARDANT HEALTH INC | GH | 4.43% | |
| NATERA INC | NTRA | 4.28% | |
| CAREDX INC | CDNA | 4.00% | |
| ILLUMINA INC | ILMN | 3.96% |
Period by period
| Window | Total return | S&P 500 | Gap to S&P 500 | Gap to Nasdaq-100 |
|---|---|---|---|---|
| 3 months | +36.1% | +3.3% | +32.8 pts | +36.9 pts |
| 6 months | +72.8% | +16.0% | +56.8 pts | +52.1 pts |
| 1 year | +74.0% | +17.5% | +56.5 pts | +51.0 pts |
| 3 years | +44.5% | +77.9% | −33.4 pts | −50.6 pts |
| Since launch | +142.3% | +361.8% | −219.5 pts | −529.3 pts |
In plain words
The top ten holdings are 59% of the fund across 33 positions, as published by its issuer for Sep 11, 2026. Over the year to Sep 11, 2026 the fund returned +74.0% with distributions reinvested against +17.5% for the S&P 500, so a holder was ahead by 56.5 pts. It sits 59.2% below its all-time high of Jan 20, 2021.
| Theme (ETFIQ, editorial) | Biotech and genomics |
|---|---|
| Launched | Oct 31, 2014 |
| Already in the S&P 500, by weight (ETFIQ) | 3.9% |
| Active share vs the S&P 500 (ETFIQ) | 98.5% |
| Already in the Nasdaq-100, by weight (ETFIQ) | 0.0% |
| Active share vs the Nasdaq-100 (ETFIQ) | 100.0% |
| Top ten holdings weight | 59.3% |
| Holdings | 33 |
| Holdings as of (the issuer’s daily file) | Sep 11, 2026 |
| Top holdings | 10X GENOMICS INC-CLASS A 10.3%, TWIST BIOSCIENCE CORP 8.3%, TEMPUS AI INC-CL A 7.7%, CRISPR THERAPEUTICS AG 5.9%, PERSONALIS INC 5.9%, ABSCI CORP 4.6%, GUARDANT HEALTH INC 4.4%, NATERA INC 4.3%, CAREDX INC 4.0%, ILLUMINA INC 4.0% |
| Net assets (the issuer daily holdings, added up, as of Sep 11, 2026) | $1.8bn |
| Below its all-time high (ETFIQ) | −59.2% |
| Expense ratio (485BPOS XBRL, Nov 26, 2025) | 0.75% |
| Fee for the part that differs from the S&P 500, active expense ratio (ETFIQ) | 0.76% |
| Closest funds by holdings overlap | GNOM 40%, WDNA 27%, ARKK 26%, HELX 25%, EKG 24% |
Holdings from the file the issuer publishes daily; overlap and active share computed by ETFIQ against the IVV and QQQM books; returns from Tiingo end-of-day prices with distributions reinvested. How these figures are computed
Questions people ask
- How much of ARKG is in S&P 500 companies?
- By its holdings published by its issuer for Sep 11, 2026, 4% of ARKG by weight is stocks the S&P 500 already holds. Its active share against the index is 98%, so that share is the part doing something different.
- What does ARKG hold?
- 33 positions as published by its issuer for Sep 11, 2026, with the top ten at 59% of the fund. The largest are 10X GENOMICS INC-CLASS A at 10.3%, TWIST BIOSCIENCE CORP at 8.3%, TEMPUS AI INC-CL A at 7.7%.
- Has ARKG beaten the S&P 500?
- Over the year to Sep 11, 2026 ARKG returned +74.0% with distributions reinvested, against +17.5% for the S&P 500, so it finished ahead of the index by 56.5 points.
- What does ARKG cost?
- The prospectus expense ratio is 0.75% a year. Because 98% of the fund differs from the S&P 500, the fee on that differing part works out at 0.76%.
The words on this page
- Active share
- The part of the fund doing something the index is not, as a percentage. It is the part a fee is actually buying.
- Weight overlap
- The share of money two portfolios hold in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice.
- Already in the index
- The fund’s weight in securities the S&P 500 holds at all. A fund can be made entirely of index names and still have high active share, because it holds them at very different weights.
- Top ten
- What the ten largest positions add up to. The higher it is, the more the fund is a bet on a few companies rather than a theme.
Every term used here, defined in full on the thematic ETFs vocabulary page.
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
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Cite this page. ETFIQ, ARKG, thematic ETFs, data as of Sep 11, 2026. https://etfiq.com/funds/arkg Free to use with attribution; the underlying files are at Open data.