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Data as of .

ARKG vs IDNA: which is really different?

ARKG and IDNA hold 10% of their weight in the same names, and ARKG returned more over the year.

ARK Genomic Revolution ETF and iShares Genomics Immunology and Healthcare ETF.

3.5%ARKG in the S&P 500
23.9%IDNA in the S&P 500
+87.1%ARKG total return, 1 year
+73.4%IDNA total return, 1 year

ETFIQ Off-Index Score: IDNA scores higher

How much of it is not the index it is sold as an alternative to?

ARKG 55.9IDNA 64.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

ARKG97% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
4%97%inof its weight outside the S&P 500active share 99% · top ten 60% of the fund · 33 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in4%97%4% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 60% of the fund
IDNA76% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
24%76%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 46% of the fund · 62 holdings filed Sep 17, 2026 · Nasdaq-100: 7% in24%76%inoutside the S&P 500active share 99% · top ten 46% of the fund

10% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, ARKG and IDNA hold 10% of their money in the same securities at the same weight.

Positions ARKG and IDNA both hold, largest shared weight first
HoldingARKGIDNA
TWIST BIOSCIENCE CORP9.63%7.09%
CRISPR THERAPEUTICS AG5.63%1.50%
PERSONALIS INC5.16%0.94%
INTELLIA THERAPEUTICS INC1.49%0.47%
PACIFIC BIOSCIENCES OF CALIF0.70%0.36%
PRIME MEDICINE INC1.12%0.09%
Only in each
Only in ARKGOnly in IDNA
10X GENOMICS INC-CLASS A 9.39%MODERNA 9.54%
TEMPUS AI INC-CL A 8.92%GENMAB 4.13%
GUARDANT HEALTH INC 4.87%BAYER AG 3.87%
ABSCI CORP 4.76%REVOLUTION MEDICINES 3.76%
NATERA INC 4.25%IOVANCE BIOTHERAPEUTICS INC 3.67%
ILLUMINA INC 4.13%REGENERON PHARMACEUTICALS 3.63%
CAREDX INC 3.78%TAKEDA PHARMACEUTICAL 3.62%
ELI LILLY & CO 3.51%INCYTE CORP 3.60%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 21, 2026.

Performance, window by window

ARKG and IDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
ARKGIDNAARKGIDNAARKGIDNA
3 months+40.1%+30.3%+37.9 pts+28.1 pts+42.6 pts+32.8 pts
6 months+98.2%+41.4%+80.2 pts+23.4 pts+74.0 pts+17.2 pts
1 year+87.1%+73.4%+70.6 pts+56.9 pts+65.4 pts+51.7 pts
3 years+74.8%+91.3%−3.6 pts+12.9 pts−23.4 pts−6.9 pts
Since launch+174.6%+69.7%−186.8 pts−123.9 pts−504.0 pts−242.0 pts
Open the live comparison on ETFIQ
ARKG and IDNA on the same fields, as of Sep 18, 2026. Source: ETFIQ.
ARKG
ARK Genomic Revolution ETF
Holds 33 stocks in genomics and gene editing, 4% of its weight in S&P 500 companies
IDNA
iShares Genomics Immunology and Healthcare ETF
Holds 62 stocks in genomics and gene editing, 24% of its weight in S&P 500 companies
IssuerARKiShares
ThemeGenomics and gene editingGenomics and gene editing
In the S&P 5003.5%23.9%
Active share vs the S&P 50098.5%99.1%
In the Nasdaq-1000.0%7.0%
Holdings3362
Top ten, share of the fund60.4%46.2%
Expense ratio0.75%0.47%
Fee for the differing part0.76%0.47%
Total return, 1 year+87.1%+73.4%
vs the S&P 500+70.6 pts+56.9 pts
vs the Nasdaq-100+65.4 pts+51.7 pts
Below its high−53.8%−24.7%
Net assets$2.2bn$271m

ARKG in plain words

By weight, 4% of ARKG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 60% of the fund across 33 positions, as published by its issuer for Sep 21, 2026. Over the year to Sep 18, 2026 the fund returned +87.1% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 70.6 pts. It sits 53.8% below its all-time high of Jan 20, 2021.

IDNA in plain words

By weight, 24% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 46% of the fund across 62 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +73.4% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 56.9 pts. It sits 24.7% below its all-time high of Sep 2, 2021.

Questions people ask

Do ARKG and IDNA hold the same stocks?
By their latest filings, 10% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, ARKG or IDNA?
ARKG has 4% of its weight in S&P 500 names and IDNA has 24%, so IDNA differs more from the index.
Which is cheaper, ARKG or IDNA?
ARKG charges 0.75% a year and IDNA charges 0.47%, so IDNA is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

ARKG against IDNA, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, ARKG against IDNA, data as of Sep 18, 2026. https://etfiq.com/compare/themes/arkg-vs-idna Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources