Do IDNA and PBPH hold the same stocks?

By their latest filings, 21% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.

Which is more different from the S&P 500, IDNA or PBPH?

IDNA has 27% of its weight in S&P 500 names and PBPH has 59%, so IDNA differs more from the index.

Which is cheaper, IDNA or PBPH?

IDNA charges 0.47% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Data as of Nov 4, 2026.

Thematic ETFs

IDNA vs PBPH: Holdings Overlap & Returns

Share on X Download as PDF

IDNA and PBPH hold 21% of their weight in the same names.

askIQ about this page

askIQ about IDNA and PBPH

Net assets: $340m on Nov 3, 2026 for iShares Genomics Immunology and Healthcare ETF, and $952m on Jul 31, 2026 for Portfolio Building Block World Pharma and Biotech Index ETF.

IDNA on its own →PBPH on its own →

At a glance

27.4%

IDNA in the S&P 500

59.2%

PBPH in the S&P 500

+81.1%

IDNA total return, 1 year

+27.0%

PBPH total return, since launch, Nov 25, 2025

IDNA · 1 year to Nov 4, 2026 73% of its weight is outside the S&P 500

27% of IDNA's weight is in S&P 500 companies and 73% is outside the index. Holdings as of Nov 3, 2026.

PBPH · 6 months to Nov 4, 2026 41% of its weight is outside the S&P 500

59% of PBPH's weight is in S&P 500 companies and 41% is outside the index. Holdings as of Jul 31, 2026.

Pair scorecard

PBPH costs 0.34 points a year less.

IDNA vs PBPH: Holdings Overlap & Returns
Measure	IDNA	PBPH
Return
Measure	IDNA	PBPH
Total return, 1 year	+81.1%	not published
Drawdown
Measure	IDNA	PBPH
Below its all-time high	16.5%, high on Sep 2, 2021
Benchmark
Measure	IDNA	PBPH
What it tracks	Genomics and gene editing	Biotech
Cost and size
Measure	IDNA	PBPH
Expense ratio	0.47%	0.13%
Net assets, IDNA as of Nov 3, 2026 and PBPH as of Jul 31, 2026	$340m	$952m
Holdings
Measure	IDNA	PBPH
Holdings in common	21%

Method

What they share

21%

By the books each fund has filed, IDNA and PBPH hold 21% of their money in the same securities at the same weight. Holdings dated Jul 31, 2026 and Nov 3, 2026.

50%

0 half 100%

half

21% in common

Positions both hold · largest shared weight first IDNA PBPH

MERCK & CO INC 3.32% 5.04%

ROCHE PS PAR AG 3.20% 4.74%

VERTEX PHARMACEUTICALS 3.29% 2.82%

GLAXOSMITHKLINE 2.62% 2.26%

SANOFI SA 2.79% 2.17%

REGENERON PHARMACEUTICALS 4.24% 1.79%

BAYER AG 3.85% 1.27%

TAKEDA PHARMACEUTICAL 3.77% 1.25%

REVOLUTION MEDICINES 3.60% 0.77%

INCYTE CORP 3.18% 0.56%

MODERNA 13.33% 0.45%

GENMAB 6.26% 0.40%

Only in one fund ↓

Only in IDNA

TWIST BIOSCIENCE 5.61%

CARIS LIFE SCIENCES 3.50%

IOVANCE BIOTHERAPEUTICS INC 2.98%

BIONTECH SE ADR 2.73%

IMMUNITYBIO 2.71%

IPSEN SA 2.61%

ABCELLERA BIOLOGICS 2.48%

IDEAYA BIOSCIENCES 2.26%

Only in PBPH

ELI LILLY & COMPANY 15.20%

JOHNSON & JOHNSON 9.66%

ABBVIE INC 6.94%

AMGEN INC 4.63%

NOVARTIS AG 4.47%

ASTRAZENECA PLC 3.90%

GILEAD SCIENCES INC 3.77%

NOVO NORDISK A/S 3.51%

Check overlap with more funds →

Window by window

Window by window: IDNA vs PBPH: Holdings Overlap & Returns
	Total return
Window	IDNA	PBPH
3 months	+32.4%	+16.2%
6 months	+45.6%	+25.6%
1 year	+81.1%	–
3 years	+134.8%	–
Since launchNot the same days: IDNA Jun 2019 · PBPH Nov 2025	+88.1%	+27.0%

– means no data for this window. Open this comparison in the app →

Side by side

IDNA iShares Genomics Immunology and Healthcare ETF · Holds 52 stocks in genomics and gene editing, 27% of its weight in S&P 500 companies PBPH Portfolio Building Block World Pharma and Biotech Index ETF · Holds 53 stocks in biotech, 59% of its weight in S&P 500 companies

Issuer iShares Portfolio Building Block

Theme Genomics and gene editing Biotech

In the S&P 500 27.4% 59.2%

Active share vs the S&P 500 99.1% 95.0%

In the Nasdaq-100 7.5% 13.6%

Holdings 52 53

Top ten, share of the fund 51.3% 61.9%

Expense ratio 0.47% 0.13%

Fee for the differing part 0.47% 0.14%

Total return, 1 year +81.1% +27.0% (since launch, Nov 25, 2025)

vs its benchmark not measured not measured

Below its high −16.5% 0.0%

Net assets, IDNA as of Nov 3, 2026 and PBPH as of Jul 31, 2026 $340m $952m

As of Nov 4, 2026. Source: ETFIQ.

21% of the two portfolios are the same securities at the same weight.

Alert

About each fund

IDNA

By weight, 27% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 51% of the fund across 52 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +81.1% with distributions reinvested. It sits 16.5% below its all-time high of Sep 2, 2021.

PBPH

By weight, 59% of PBPH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 95%. The top ten holdings are 62% of the fund across 53 positions, as filed for Jul 31, 2026. Since it first traded on Nov 25, 2025 the fund returned +27.0% with distributions reinvested.

Questions people ask

Do IDNA and PBPH hold the same stocks?: By their latest filings, 21% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, IDNA or PBPH?: IDNA has 27% of its weight in S&P 500 names and PBPH has 59%, so IDNA differs more from the index.
Which is cheaper, IDNA or PBPH?: IDNA charges 0.47% a year and PBPH charges 0.13%, so PBPH is cheaper. Fees come from each fund's prospectus.

Other comparisons

IDNA vs PBE IDNA vs XBI IDNA vs IBB IDNA vs BBC PBPH vs ARKG PBPH vs GNOM PBPH vs GNMX PBPH vs IBB

Where to next

All thematic ETFs ranked by the S&P 500 Difference Score →How the scores are computed →IDNA on its own →PBPH on its own →IDNA dividend history →IDNA holdings →PBPH dividend history →PBPH holdings →Method →Standards and sources →

Sources and dates

IDNA filings on SEC EDGAR ↗

IDNA prospectus with the expense ratio (SEC) ↗

iShares page for IDNA ↗

PBPH filings on SEC EDGAR ↗

PBPH prospectus with the expense ratio (SEC) ↗

Portfolio Building Block page for PBPH ↗

Links are sources, not endorsements. A comparison is not a recommendation.

How this is computed

Overlap adds up the smaller of the two weights for each security both funds hold.

Every number is an ETFIQ calculation with distributions reinvested.

Cite this pageCitation, APA and Markdown

ETFIQ, IDNA against PBPH, data as of Nov 4, 2026. https://etfiq.com/compare/themes/idna-vs-pbph

Open data →

Free to use with attribution for data ETFIQ computes; issuer data stays under its owner's terms.