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Data as of .

ARKG vs GNOM: which is really different?

ARKG and GNOM hold 42% of their weight in the same names, and ARKG returned more over the year.

ARK Genomic Revolution ETF and Global X Genomics & Biotechnology ETF.

3.5%ARKG in the S&P 500
20.9%GNOM in the S&P 500
+87.1%ARKG total return, 1 year
+77.5%GNOM total return, 1 year

ETFIQ Off-Index Score: ARKG scores higher

How much of it is not the index it is sold as an alternative to?

ARKG 55.9GNOM 44.50.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

ARKG97% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
4%97%inof its weight outside the S&P 500active share 99% · top ten 60% of the fund · 33 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in4%97%4% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 60% of the fund
GNOM79% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
21%79%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 53% of the fund · 52 holdings filed Sep 18, 2026 · Nasdaq-100: 5% in21%79%inoutside the S&P 500active share 98% · top ten 53% of the fund

42% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, ARKG and GNOM hold 42% of their money in the same securities at the same weight.

Positions ARKG and GNOM both hold, largest shared weight first
HoldingARKGGNOM
TWIST BIOSCIENCE CORP9.63%7.40%
10X GENOMICS INC-CLASS A9.39%6.53%
GUARDANT HEALTH INC4.87%5.78%
NATERA INC4.25%5.13%
ILLUMINA INC4.13%5.30%
CRISPR THERAPEUTICS AG5.63%2.89%
GENEDX HOLDINGS CORP2.43%1.96%
CAREDX INC3.78%1.85%
ELI LILLY & CO3.51%1.79%
VERACYTE INC1.76%2.33%
BEAM THERAPEUTICS INC2.93%1.75%
INTELLIA THERAPEUTICS INC1.49%1.03%
Only in each
Only in ARKGOnly in GNOM
TEMPUS AI INC-CL A 8.92%MODERNA INC 7.99%
ABSCI CORP 4.76%GENSCRIPT BIOTECH CORP 4.29%
COMPASS PATHWAYS PLC 3.25%BIO-TECHNE CORP 3.56%
SCHRODINGER INC 3.04%BIOMARIN PHARMACEUTICAL INC 3.41%
RECURSION PHARMACEUTICALS-A 2.50%VERTEX PHARMACEUTICALS INC 3.35%
ADAPTIVE BIOTECHNOLOGIES 2.43%QIAGEN N.V. 3.13%
ARCTURUS THERAPEUTICS HOLDIN 2.11%CARIS LIFE SCIENCES INC 2.72%
NURIX THERAPEUTICS INC 2.05%ARROWHEAD PHARMACEUTICALS IN 2.59%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026 and Sep 21, 2026.

Performance, window by window

ARKG and GNOM over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
ARKGGNOMARKGGNOMARKGGNOM
3 months+40.1%+27.6%+37.9 pts+25.4 pts+42.6 pts+30.1 pts
6 months+98.2%+56.4%+80.2 pts+38.4 pts+74.0 pts+32.2 pts
1 year+87.1%+77.5%+70.6 pts+60.9 pts+65.4 pts+55.7 pts
3 years+74.8%+59.3%−3.6 pts−19.1 pts−23.4 pts−38.9 pts
Since launch+174.6%+9.8%−186.8 pts−185.2 pts−504.0 pts−297.4 pts
Open the live comparison on ETFIQ
ARKG and GNOM on the same fields, as of Sep 18, 2026. Source: ETFIQ.
ARKG
ARK Genomic Revolution ETF
Holds 33 stocks in genomics and gene editing, 4% of its weight in S&P 500 companies
GNOM
Global X Genomics & Biotechnology ETF
Holds 52 stocks in genomics and gene editing, 21% of its weight in S&P 500 companies
IssuerARKGlobal X
ThemeGenomics and gene editingGenomics and gene editing
In the S&P 5003.5%20.9%
Active share vs the S&P 50098.5%97.6%
In the Nasdaq-1000.0%5.0%
Holdings3352
Top ten, share of the fund60.4%52.7%
Expense ratio0.75%0.50%
Fee for the differing part0.76%0.51%
Total return, 1 year+87.1%+77.5%
vs the S&P 500+70.6 pts+60.9 pts
vs the Nasdaq-100+65.4 pts+55.7 pts
Below its high−53.8%−39.6%
Net assets$2.2bn$100m

ARKG in plain words

By weight, 4% of ARKG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 60% of the fund across 33 positions, as published by its issuer for Sep 21, 2026. Over the year to Sep 18, 2026 the fund returned +87.1% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 70.6 pts. It sits 53.8% below its all-time high of Jan 20, 2021.

GNOM in plain words

By weight, 21% of GNOM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 53% of the fund across 52 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +77.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 60.9 pts. It sits 39.6% below its all-time high of Feb 8, 2021.

Questions people ask

Do ARKG and GNOM hold the same stocks?
By their latest filings, 42% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, ARKG or GNOM?
ARKG has 4% of its weight in S&P 500 names and GNOM has 21%, so ARKG differs more from the index.
Which is cheaper, ARKG or GNOM?
ARKG charges 0.75% a year and GNOM charges 0.50%, so GNOM is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

ARKG against GNOM, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, ARKG against GNOM, data as of Sep 18, 2026. https://etfiq.com/compare/themes/arkg-vs-gnom Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources