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Data as of .

ARKG vs IBBQ: which is really different?

ARKG and IBBQ hold 9% of their weight in the same names, and ARKG returned more over the year.

ARK Genomic Revolution ETF and Invesco Nasdaq Biotechnology ETF.

3.5%ARKG in the S&P 500
38.6%IBBQ in the S&P 500
+87.1%ARKG total return, 1 year
+44.6%IBBQ total return, 1 year

ETFIQ Off-Index Score: IBBQ scores higher

How much of it is not the index it is sold as an alternative to?

ARKG 55.9IBBQ 61.70.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

ARKG97% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
4%97%inof its weight outside the S&P 500active share 99% · top ten 60% of the fund · 33 holdings filed Sep 18, 2026 · Nasdaq-100: 0% in4%97%4% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 60% of the fund
IBBQ61% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
39%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 45% of the fund · 256 holdings filed Sep 19, 2026 · Nasdaq-100: 33% in39%61%in the S&P 500outside the S&P 500active share 99% · top ten 45% of the fund

9% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, ARKG and IBBQ hold 9% of their money in the same securities at the same weight.

Positions ARKG and IBBQ both hold, largest shared weight first
HoldingARKGIBBQ
ILLUMINA INC4.13%2.43%
GUARDANT HEALTH INC4.87%1.59%
TEMPUS AI INC-CL A8.92%0.91%
TWIST BIOSCIENCE CORP9.63%0.70%
10X GENOMICS INC-CLASS A9.39%0.60%
IONIS PHARMACEUTICALS INC1.60%0.49%
CRISPR THERAPEUTICS AG5.63%0.37%
ADAPTIVE BIOTECHNOLOGIES2.43%0.31%
VERACYTE INC1.76%0.21%
NURIX THERAPEUTICS INC2.05%0.18%
BEAM THERAPEUTICS INC2.93%0.17%
COMPASS PATHWAYS PLC3.25%0.14%
Only in each
Only in ARKGOnly in IBBQ
NATERA INC 4.25%Amgen Inc 8.05%
CAREDX INC 3.78%Vertex Pharmaceuticals Inc 7.98%
SCHRODINGER INC 3.04%Gilead Sciences Inc 7.89%
GENEDX HOLDINGS CORP 2.43%Regeneron Pharmaceuticals Inc 5.42%
BUTTERFLY NETWORK INC 1.80%Moderna Inc 4.10%
ALAMAR BIOSCIENCES INC 1.60%Revolution Medicines Inc 2.72%
GENERATE BIOMEDICINES INC 1.26%Alnylam Pharmaceuticals Inc 2.14%
908 DEVICES INC 0.96%Biogen Inc 2.13%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 19, 2026 and Sep 21, 2026.

Performance, window by window

ARKG and IBBQ over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
ARKGIBBQARKGIBBQARKGIBBQ
3 months+40.1%+15.8%+37.9 pts+13.6 pts+42.6 pts+18.3 pts
6 months+98.2%+24.9%+80.2 pts+6.9 pts+74.0 pts+0.7 pts
1 year+87.1%+44.6%+70.6 pts+28.0 pts+65.4 pts+22.8 pts
3 years+74.8%+76.7%−3.6 pts−1.7 pts−23.4 pts−21.5 pts
Since launch+174.6%+42.0%−186.8 pts−51.2 pts−504.0 pts−76.1 pts
Open the live comparison on ETFIQ
ARKG and IBBQ on the same fields, as of Sep 18, 2026. Source: ETFIQ.
ARKG
ARK Genomic Revolution ETF
Holds 33 stocks in genomics and gene editing, 4% of its weight in S&P 500 companies
IBBQ
Invesco Nasdaq Biotechnology ETF
Holds 256 stocks in biotech, 39% of its weight in S&P 500 companies
IssuerARKInvesco
ThemeGenomics and gene editingBiotech
In the S&P 5003.5%38.6%
Active share vs the S&P 50098.5%99.0%
In the Nasdaq-1000.0%33.2%
Holdings33256
Top ten, share of the fund60.4%44.8%
Expense ratio0.75%0.19%
Fee for the differing part0.76%0.19%
Total return, 1 year+87.1%+44.6%
vs the S&P 500+70.6 pts+28.0 pts
vs the Nasdaq-100+65.4 pts+22.8 pts
Below its high−53.8%−5.8%
Net assets$2.2bn$96m

ARKG in plain words

By weight, 4% of ARKG's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 60% of the fund across 33 positions, as published by its issuer for Sep 21, 2026. Over the year to Sep 18, 2026 the fund returned +87.1% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 70.6 pts. It sits 53.8% below its all-time high of Jan 20, 2021.

IBBQ in plain words

By weight, 39% of IBBQ's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 256 positions, as published by its issuer for Sep 19, 2026. Over the year to Sep 18, 2026 the fund returned +44.6% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 28.0 pts. It sits 5.8% below its all-time high of Aug 19, 2026.

Questions people ask

Do ARKG and IBBQ hold the same stocks?
By their latest filings, 9% of their books are the same securities at the same weight, which is mostly different names. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, ARKG or IBBQ?
ARKG has 4% of its weight in S&P 500 names and IBBQ has 39%, so IBBQ differs more from the index.
Which is cheaper, ARKG or IBBQ?
ARKG charges 0.75% a year and IBBQ charges 0.19%, so IBBQ is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

ARKG against IBBQ, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, ARKG against IBBQ, data as of Sep 18, 2026. https://etfiq.com/compare/themes/arkg-vs-ibbq Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources