GNOM vs IBB: which is really different?
GNOM and IBB hold 25% of their weight in the same names, and GNOM returned +65.7% over the year. Global X Genomics & Biotechnology ETF and iShares Biotechnology ETF.
IBB costs 0.06 points a year less; their one-year returns differ by 29.6 points; IBB is far larger, $10.8bn against $104m.
| GNOM | IBB | |
|---|---|---|
| Expense ratio | 0.50% | 0.44% |
| Net assets | $104m | $10.8bn |
| Total return, 1 year | +65.7% | +36.1% |
| What it tracks | Genomics and gene editing | Biotech |
| Holdings in common | 25% | |
| S&P 500, total return, 1 year | +17.3% | |
| Against the S&P 500, 1 year | ahead by 48.5 pts | ahead by 18.8 pts |
| Below its all-time high | 37.4%, high on Feb 8, 2021 | |
Holdings in common uses holdings dated Oct 8, 2026 and Oct 9, 2026.
24% of GNOM's weight is in S&P 500 companies and 76% is outside the index. Holdings as of Oct 9, 2026.
40% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.
A percentile among the 391 thematic ETFs with a holdings filing. All thematic ETFs ranked by it → How it is computed →
What they hold in common
By the books each fund has filed, GNOM and IBB hold 25% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Oct 8, 2026 and Oct 9, 2026.
half
25% in common
25% of the two portfolios are the same securities at the same weight.
Performance, window by window
| Total return | vs the S&P 500 | vs the Nasdaq-100 | ||||
|---|---|---|---|---|---|---|
| Window | GNOM | IBB | GNOM | IBB | GNOM | IBB |
| 3 months | +21.4% | +7.5% | +18.0 pts | +4.1 pts | +17.7 pts | +3.9 pts |
| 6 months | +56.8% | +21.9% | +41.6 pts | +6.8 pts | +33.6 pts | −1.3 pts |
| 1 year | +65.7% | +36.1% | +48.5 pts | +18.8 pts | +42.1 pts | +12.5 pts |
| 3 years | +72.0% | +69.1% | −13.7 pts | −16.7 pts | −35.2 pts | −38.2 pts |
| Since launch GNOM Apr 2019 · IBB Feb 2001 | +13.7% | +525.3% | −187.8 pts | −299.7 pts | −310.8 pts | −936.3 pts |
Source: ETFIQ. Open the live comparison on ETFIQ →
On the same fields
As of Oct 9, 2026. Source: ETFIQ.
GNOM in plain words
By weight, 24% of GNOM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 56% of the fund across 50 positions, as published by its issuer for Oct 9, 2026. Over the year to Oct 9, 2026 the fund returned +65.7% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 48.5 pts. It sits 37.4% below its all-time high of Feb 8, 2021.
IBB in plain words
By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +36.1% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 18.8 pts.
Questions people ask
- Do GNOM and IBB hold the same stocks?
- By their latest filings, 25% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
ETFIQ links to the documents behind every figure; a link is not an endorsement. A comparison is not a recommendation.
How this is computed
It is a position in a set, not a rating, and neither end of it is a recommendation.
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.
Every figure is an ETFIQ calculation with distributions reinvested.
ETFIQ, GNOM against IBB, data as of Oct 9, 2026. https://etfiq.com/compare/themes/gnom-vs-ibb
ETFIQ. (Oct 9, 2026). GNOM against IBB. Retrieved from https://etfiq.com/compare/themes/gnom-vs-ibb
[GNOM against IBB (ETFIQ, Oct 9, 2026)](https://etfiq.com/compare/themes/gnom-vs-ibb)
Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms.