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Data as of .

BBH vs GNOM: which is really different?

BBH and GNOM hold 26% of their weight in the same names, and GNOM returned more over the year.

VanEck Biotech ETF and Global X Genomics & Biotechnology ETF.

60.4%BBH in the S&P 500
20.9%GNOM in the S&P 500
+40.5%BBH total return, 1 year
+77.5%GNOM total return, 1 year

ETFIQ Off-Index Score: BBH scores higher

How much of it is not the index it is sold as an alternative to?

BBH 61.7GNOM 44.50.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

BBH40% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
60%40%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 72% of the fund · 24 holdings filed Sep 17, 2026 · Nasdaq-100: 47% in60%40%in the S&P 500outsideactive share 99% · top ten 72% of the fund
GNOM79% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
21%79%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 53% of the fund · 52 holdings filed Sep 18, 2026 · Nasdaq-100: 5% in21%79%inoutside the S&P 500active share 98% · top ten 53% of the fund

26% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, BBH and GNOM hold 26% of their money in the same securities at the same weight.

Positions BBH and GNOM both hold, largest shared weight first
HoldingBBHGNOM
Moderna Inc5.05%7.99%
Natera Inc4.97%5.13%
Illumina Inc3.68%5.30%
Vertex Pharmaceuticals Inc8.32%3.35%
Guardant Health Inc3.15%5.78%
Gilead Sciences Inc13.81%1.63%
Biontech Se1.62%2.55%
Biomarin Pharmaceutical Inc1.25%3.41%
Bio-Techne Corp1.21%3.56%
Qiagen Nv0.96%3.13%
Only in each
Only in BBHOnly in GNOM
Amgen Inc 15.03%TWIST BIOSCIENCE CORP 7.40%
Regeneron Pharmaceuticals Inc 7.00%10X GENOMICS INC-CLASS A 6.53%
Argenx Se 4.93%GENSCRIPT BIOTECH CORP 4.29%
Iqvia Holdings Inc 4.61%CRISPR THERAPEUTICS AG 2.89%
Revolution Medicines Inc 4.09%CARIS LIFE SCIENCES INC 2.72%
Beone Medicines Ltd 2.75%ARROWHEAD PHARMACEUTICALS IN 2.59%
Alnylam Pharmaceuticals Inc 2.73%PRAXIS PRECISION MEDICINES I 2.56%
Biogen Inc 2.71%VERACYTE INC 2.33%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026.

Performance, window by window

BBH and GNOM over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
BBHGNOMBBHGNOMBBHGNOM
3 months+24.8%+27.6%+22.5 pts+25.4 pts+27.3 pts+30.1 pts
6 months+29.0%+56.4%+11.0 pts+38.4 pts+4.8 pts+32.2 pts
1 year+40.5%+77.5%+23.9 pts+60.9 pts+18.7 pts+55.7 pts
3 years+48.9%+59.3%−29.5 pts−19.1 pts−49.3 pts−38.9 pts
Since launch+732.7%+9.8%−70.8 pts−185.2 pts−957.5 pts−297.4 pts
Open the live comparison on ETFIQ
BBH and GNOM on the same fields, as of Sep 18, 2026. Source: ETFIQ.
BBH
VanEck Biotech ETF
Holds 24 stocks in biotech, 60% of its weight in S&P 500 companies
GNOM
Global X Genomics & Biotechnology ETF
Holds 52 stocks in genomics and gene editing, 21% of its weight in S&P 500 companies
IssuerVanEckGlobal X
ThemeBiotechGenomics and gene editing
In the S&P 50060.4%20.9%
Active share vs the S&P 50099.0%97.6%
In the Nasdaq-10047.2%5.0%
Holdings2452
Top ten, share of the fund72.4%52.7%
Expense ratio0.35%0.50%
Fee for the differing part0.35%0.51%
Total return, 1 year+40.5%+77.5%
vs the S&P 500+23.9 pts+60.9 pts
vs the Nasdaq-100+18.7 pts+55.7 pts
Below its high−4.0%−39.6%
Net assets$470m$100m

BBH in plain words

By weight, 60% of BBH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 72% of the fund across 24 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +40.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 23.9 pts.

GNOM in plain words

By weight, 21% of GNOM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 53% of the fund across 52 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +77.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 60.9 pts. It sits 39.6% below its all-time high of Feb 8, 2021.

Questions people ask

Do BBH and GNOM hold the same stocks?
By their latest filings, 26% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBH or GNOM?
BBH has 60% of its weight in S&P 500 names and GNOM has 21%, so BBH differs more from the index.
Which is cheaper, BBH or GNOM?
BBH charges 0.35% a year and GNOM charges 0.50%, so BBH is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

BBH against GNOM, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, BBH against GNOM, data as of Sep 18, 2026. https://etfiq.com/compare/themes/bbh-vs-gnom Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources