Data as of Nov 4, 2026.

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Thematic ETFs

BBH vs GNOM: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, BBH returned +47.2% to GNOM's +66.6%; 27% of their weight is in the same names.

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Net assets: $525m on Nov 3, 2026 for VanEck Biotech ETF, and $104m on Oct 12, 2026 for Global X Genomics & Biotechnology ETF.

At a glance
64.4%
BBH in the S&P 500
21.0%
GNOM in the S&P 500
+47.2%
BBH total return, 1 year
+66.6%
GNOM total return, 1 year
BBH · 1 year to Nov 4, 2026 36% of its weight is outside the S&P 500
36% of its weight is outside the S&P 50064% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.64%36%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 74% of the fund · 25 holdings as published by its issuer for Nov 2, 2026 · Nasdaq-100: 49% in36% of its weight is outside the S&P 50064% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.64%36%in the S&P 500outsideactive share 99% · Nasdaq-100: 49% in

64% of BBH's weight is in S&P 500 companies and 36% is outside the index. Holdings as of Nov 2, 2026.

GNOM · 1 year to Nov 4, 2026 79% of its weight is outside the S&P 500
79% of its weight is outside the S&P 50021% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.21%79%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 49% of the fund · 50 holdings as filed for Aug 31, 2026 · Nasdaq-100: 5% in79% of its weight is outside the S&P 50021% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.21%79%inoutside the S&P 500active share 98% · Nasdaq-100: 5% in

21% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.

Pair scorecard

BBH costs 0.15 points a year less; their one-year returns differ by 19.4 points; BBH is 4.6 times larger.

BBH vs GNOM: Holdings Overlap & Returns
MeasureBBHGNOM
Return
Total return, 1 year+47.2%+66.6%
Drawdown
Below its all-time high36.2%, high on Feb 8, 2021
Benchmark
What it tracksBiotechGenomics and gene editing
Cost and size
Expense ratio0.35%0.50%
Net assets, as of Oct 12, 2026$482m$104m
Holdings
Holdings in common27%

Method

Risk and return

Apr 18, 2019 to Oct 30, 2026 · 393 weekly returns
BBH GNOM
Return
Total return edge BBH +121.3% +25.4%
Annualized edge BBH +11.1% +3.0%
Price return edge BBH +114.6% +23.4%
Risk
Volatility edge BBH 22.2% 32.9%
Max drawdown edge BBH −37.7% −73.5%
Risk-adjusted
Sharpe edge BBH 0.46 0.17
Sortino edge BBH 0.68 0.25
Calmar edge BBH 0.29 0.04
Reading

From Apr 2019 to Oct 2026, BBH returned more: +121.3% to +25.4%. BBH swung less: 22.2% to 32.9%. BBH fell less at its worst: −37.7% to −73.5%.

Full scorecard

9 measures, with how each is measured
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Risk and return: BBH vs GNOM: Holdings Overlap & Returns
MeasureBBHGNOMEdgeHow it is measured
Return
Total return+121.3%+25.4%BBHPrice change plus distributions, reinvested.
Annualized+11.1%+3.0%BBHTotal return as a yearly rate.
Price return+114.6%+23.4%BBHPrice change alone, distributions left out.
Risk
Volatility22.2%32.9%BBHSpread of weekly returns, annualized. Lower is steadier.
Downside deviation14.8%22.3%BBHLike volatility, counting only weeks below the Treasury bill rate.
Max drawdown−37.7%−73.5%BBHDeepest fall from a high to the low after it.
Risk-adjusted
Sharpe0.460.17BBHReturn above Treasury bills per unit of volatility.
Sortino0.680.25BBHReturn above Treasury bills per unit of downside deviation.
Calmar0.290.04BBHAnnualized return divided by the max drawdown.

Computed by ETFIQ from Tiingo daily prices and ETFIQ's distribution records, 393 weekly returns. Cash rate: the 13-week Treasury bill.

What they share

27%

By the books each fund has filed, BBH and GNOM hold 27% of their money in the same securities at the same weight. Holdings dated Aug 31, 2026 and Nov 3, 2026.

0 half 100%

half

27% in common

Positions both hold · largest shared weight first BBH GNOM
Moderna Inc 6.88% 7.50%
Natera Inc 4.44% 4.61%
Vertex Pharmaceuticals Inc 7.98% 3.70%
Illumina Inc 3.37% 4.87%
Guardant Health Inc 2.83% 5.28%
Gilead Sciences Inc 14.17% 1.64%
Biontech Se 1.34% 2.78%
Bio-Techne Corp 1.12% 3.67%
Qiagen Nv 1.02% 3.22%
Biomarin Pharmaceutical Inc 1.00% 3.58%
Only in one fund ↓
Only in BBH
Amgen Inc 16.53%
Regeneron Pharmaceuticals Inc 7.99%
Iqvia Holdings Inc 4.18%
Argenx Se 4.13%
Revolution Medicines Inc 3.82%
Biogen Inc 2.88%
Beone Medicines Ltd 2.56%
United Therapeutics Corp 2.38%
Only in GNOM
Twist Bioscience Corporation 6.34%
10x Genomics, Inc. 5.48%
Genscript Biotech Corp 3.81%
ARROWHEAD PHARMACEUTICALS, INC. 3.31%
Praxis Precision Medicines, Inc. 3.09%
CRISPR Therapeutics AG 3.00%
Veracyte, Inc. 2.61%
CARIS LIFE SCIENCES, INC. 2.38%
Check overlap with more funds →

Window by window

Window by window: BBH vs GNOM: Holdings Overlap & Returns
Total return
WindowBBHGNOM
3 months+24.3%+24.5%
6 months+38.3%+49.4%
1 year+47.2%+66.6%
3 years+75.4%+81.6%
Since launchNot the same days: BBH Dec 2011 · GNOM Apr 2019+680.5%+16.0%

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Side by side

BBH VanEck Biotech ETF · Holds 25 stocks in biotech, 64% of its weight in S&P 500 companies GNOM Global X Genomics & Biotechnology ETF · Holds 50 stocks in genomics and gene editing, 21% of its weight in S&P 500 companies
Theme Biotech Genomics and gene editing
In the S&P 500 64.4% 21.0%
Active share vs the S&P 500 99.0% 97.6%
In the Nasdaq-100 49.1% 5.3%
Holdings 25 50
Top ten, share of the fund 73.5% 48.8%
Expense ratio 0.35% 0.50%
Fee for the differing part 0.35% 0.51%
Total return, 1 year +47.2% +66.6%
vs its benchmark not measured not measured
Below its high 0.0% −36.2%
Net assets, BBH as of Nov 3, 2026 and GNOM as of Oct 12, 2026 $525m $104m

As of Nov 4, 2026. Source: ETFIQ.

27% of the two portfolios are the same securities at the same weight.

Client brief:

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About each fund
BBH

By weight, 64% of BBH's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 74% of the fund across 25 positions, as published by its issuer for Nov 3, 2026. Over the year to Nov 4, 2026 the fund returned +47.2% with distributions reinvested.

GNOM

By weight, 21% of GNOM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 49% of the fund across 50 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +66.6% with distributions reinvested. It sits 36.2% below its all-time high of Feb 8, 2021.

Questions people ask

Do BBH and GNOM hold the same stocks?
By their latest filings, 27% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBH or GNOM?
BBH has 64% of its weight in S&P 500 names and GNOM has 21%, so BBH differs more from the index.
Which is cheaper, BBH or GNOM?
BBH charges 0.35% a year and GNOM charges 0.50%, so BBH is cheaper. Fees come from each fund's prospectus.
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ETFIQ, BBH against GNOM, data as of Nov 4, 2026. https://etfiq.com/compare/themes/bbh-vs-gnom

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