GNMX vs IBB: which is really different?

GNMX and IBB hold 31% of their weight in the same names. Corgi Genomics & Precision Medicine ETF and iShares Biotechnology ETF.

GNMX costs 0.09 points a year less; IBB is far larger, $10.8bn against $1m.

GNMXIBB
Expense ratio0.35%0.44%
Net assets$1m$10.8bn
Total return, 1 yearnot published+36.1%
What it tracksGenomics and gene editingBiotech
Holdings in common31%
S&P 500, total return, since May 6, 2026+6.6%
S&P 500, total return, 1 year+17.3%
Against the S&P 500, since May 6, 2026ahead by 39.3 pts
Against the S&P 500, 1 yearahead by 18.8 pts

Holdings in common uses holdings dated Oct 8, 2026 and Oct 9, 2026.

28.7%
GNMX in the S&P 500
39.5%
IBB in the S&P 500
+45.9%
GNMX total return, since launch
+36.1%
IBB total return, 1 year
GNMX · 3 months to Oct 9, 202671% of its weight is outside the S&P 500
71% of its weight is outside the S&P 50029% of GNMX's weight is in S&P 500 companies and 71% is outside the index. Holdings as of Oct 9, 2026.29%71%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 48% of the fund · 57 holdings as published by its issuer for Oct 9, 2026 · Nasdaq-100: 8% in71% of its weight is outside the S&P 50029% of GNMX's weight is in S&P 500 companies and 71% is outside the index. Holdings as of Oct 9, 2026.29%71%inoutside the S&P 500active share 99% · Nasdaq-100: 8% in

29% of GNMX's weight is in S&P 500 companies and 71% is outside the index. Holdings as of Oct 9, 2026.

IBB · 1 year to Oct 9, 202661% of its weight is outside the S&P 500
61% of its weight is outside the S&P 50040% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.40%61%of its weight in S&P 500 companiesof its weight outside the S&P 500active share 99% · top ten 50% of the fund · 245 holdings as published by its issuer for Oct 8, 2026 · Nasdaq-100: 33% in61% of its weight is outside the S&P 50040% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.40%61%in the S&P 500outside the S&P 500active share 99% · Nasdaq-100: 33% in

40% of IBB's weight is in S&P 500 companies and 61% is outside the index. Holdings as of Oct 8, 2026.

ETFIQ Off-Index Score · GNMX scores higherHow much of it is not the index it is sold as an alternative to?
0.1, the lowest in this set92.3, the highest

A percentile among the 391 thematic ETFs with a holdings filing. All thematic ETFs ranked by it → How it is computed →

What they hold in common

By the books each fund has filed, GNMX and IBB hold 31% of their money in the same securities at the same weight. Above 50%, holding both is close to holding one of them twice. Holdings dated Oct 8, 2026 and Oct 9, 2026.

half

31% in common

Positions both hold, largest shared weight first
Holding GNMX IBB
Vertex Pharmaceuticals Inc 5.71% 7.69%
Moderna Inc 9.96% 5.30%
Illumina Inc 4.90% 2.94%
Revolution Medicines Inc 3.14% 2.67%
Alnylam Pharmaceuticals Inc 2.48% 2.21%
Incyte Corp 2.53% 1.67%
Genmab A/S 3.00% 1.47%
Bio-Techne Corp 2.13% 0.83%
BioMarin Pharmaceutical Inc 1.84% 0.77%
Twist Bioscience Corp 2.64% 0.71%
10X Genomics Inc 3.48% 0.66%
Krystal Biotech Inc 1.77% 0.62%
Only in GNMX
Thermo Fisher Scientific Inc 8.42%
Guardant Health Inc 3.48%
QIAGEN NV 1.89%
Schrodinger Inc/United States 1.32%
NeoGenomics Inc 1.27%
Azenta Inc 0.91%
Certara Inc 0.80%
GeneDx Holdings Corp 0.72%
Only in IBB
GILEAD SCIENCES 8.37%
AMGEN INC 7.89%
REGENERON PHARMACEUTICALS 5.40%
NATERA 3.88%
ARGENX SE ADR 3.35%
BIOGEN 2.36%
BEONE MEDICINES AG 2.17%
UNITED THERAPEUTICS 1.63%

31% of the two portfolios are the same securities at the same weight.

Performance, window by window

Total returnvs the S&P 500vs the Nasdaq-100
WindowGNMXIBBGNMXIBBGNMXIBB
3 months+21.0%+7.5%+17.6 pts+4.1 pts+17.4 pts+3.9 pts
6 monthsnot published+21.9%not published+6.8 ptsnot published−1.3 pts
1 yearnot published+36.1%not published+18.8 ptsnot published+12.5 pts
3 yearsnot published+69.1%not published−16.7 ptsnot published−38.2 pts
Since launch
GNMX May 2026 · IBB Feb 2001
+45.9%+525.3%+39.3 pts−299.7 pts+37.7 pts−936.3 pts

Source: ETFIQ. Open the live comparison on ETFIQ →

On the same fields

GNMX
Corgi Genomics & Precision Medicine ETF · Holds 57 stocks in genomics and gene editing, 29% of its weight in S&P 500 companies
IBB
iShares Biotechnology ETF · Holds 245 stocks in biotech, 40% of its weight in S&P 500 companies
Issuer Corgi iShares
Theme Genomics and gene editing Biotech
In the S&P 500 28.7% 39.5%
Active share vs the S&P 500 99.4% 99.0%
In the Nasdaq-100 8.2% 33.1%
Holdings 57 245
Top ten, share of the fund 47.9% 49.9%
Expense ratio 0.35% 0.44%
Fee for the differing part 0.35% 0.44%
Total return, 1 year +45.9% (since it first traded on May 6, 2026) +36.1%
vs the S&P 500 +39.3 pts +18.8 pts
vs the Nasdaq-100 +37.7 pts +12.5 pts
Below its high −4.3% −4.8%
Net assets $1m $10.8bn

As of Oct 9, 2026. Source: ETFIQ.

GNMX in plain words

By weight, 29% of GNMX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 48% of the fund across 57 positions, as published by its issuer for Oct 9, 2026. Since it first traded on May 6, 2026 the fund returned +45.9% with distributions reinvested against +6.6% for the S&P 500, so a holder was ahead by 39.3 pts.

IBB in plain words

By weight, 40% of IBB's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 50% of the fund across 245 positions, as published by its issuer for Oct 8, 2026. Over the year to Oct 9, 2026 the fund returned +36.1% with distributions reinvested against +17.3% for the S&P 500, so a holder was ahead by 18.8 pts.

Questions people ask

Do GNMX and IBB hold the same stocks?
By their latest filings, 31% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, GNMX or IBB?
GNMX has 29% of its weight in S&P 500 names and IBB has 40%, so GNMX differs more from the index.
Which is cheaper, GNMX or IBB?
GNMX charges 0.35% a year and IBB charges 0.44%, so GNMX is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from

ETFIQ links to the documents behind every figure; a link is not an endorsement. A comparison is not a recommendation.

How this is computed

It is a position in a set, not a rating, and neither end of it is a recommendation.

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed.

Every figure is an ETFIQ calculation with distributions reinvested.

Cite this page

ETFIQ, GNMX against IBB, data as of Oct 9, 2026. https://etfiq.com/compare/themes/gnmx-vs-ibb

Open data

Free to use with attribution for figures ETFIQ computes; issuer data stays under its owner's terms.