Data as of Nov 4, 2026.

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Thematic ETFs

BBC vs GNOM: Holdings Overlap & Returns

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Over the year to Nov 4, 2026, BBC returned +45.9% to GNOM's +66.6%; 6% of their weight is in the same names.

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Net assets: $46m on Jul 31, 2026 for Virtus Biotech Clinical Trials ETF, and $104m on Oct 12, 2026 for Global X Genomics & Biotechnology ETF.

At a glance
0.0%
BBC in the S&P 500
21.0%
GNOM in the S&P 500
+45.9%
BBC total return, 1 year
+66.6%
GNOM total return, 1 year
BBC · 1 year to Nov 4, 2026 100% of its weight is outside the S&P 500
100% of its weight is outside the S&P 5000% of BBC's weight is in S&P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026.0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · top ten 12% of the fund · 131 holdings as filed for Jul 31, 2026 · Nasdaq-100: 0% in100% of its weight is outside the S&P 5000% of BBC's weight is in S&P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026.0%100%0% of its weight in S&P 500 companiesof its weight outside the S&P 500active share 100% · Nasdaq-100: 0% in

0% of BBC's weight is in S&P 500 companies and 100% is outside the index. Holdings as of Jul 31, 2026.

GNOM · 1 year to Nov 4, 2026 79% of its weight is outside the S&P 500
79% of its weight is outside the S&P 50021% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.21%79%in the S&P 500of its weight outside the S&P 500active share 98% · top ten 49% of the fund · 50 holdings as filed for Aug 31, 2026 · Nasdaq-100: 5% in79% of its weight is outside the S&P 50021% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.21%79%inoutside the S&P 500active share 98% · Nasdaq-100: 5% in

21% of GNOM's weight is in S&P 500 companies and 79% is outside the index. Holdings as of Aug 31, 2026.

Pair scorecard

GNOM costs 0.15 points a year less; their one-year returns differ by 20.7 points.

BBC vs GNOM: Holdings Overlap & Returns
MeasureBBCGNOM
Return
Total return, 1 year+45.9%+66.6%
Drawdown
Below its all-time high27.4%, high on Feb 8, 202136.2%, high on Feb 8, 2021
Benchmark
What it tracksBiotechGenomics and gene editing
Cost and size
Expense ratio0.65%0.50%
Net assets, BBC as of Jul 31, 2026 and GNOM as of Oct 12, 2026$46m$104m
Holdings
Holdings in common6%

Method

What they share

6%

By the books each fund has filed, BBC and GNOM hold 6% of their money in the same securities at the same weight. Holdings dated Jul 31, 2026 and Aug 31, 2026.

0 half 100%

half

6% in common

Positions both hold · largest shared weight first BBC GNOM
UNIQURE NV 1.06% 2.09%
PRAXIS PRECISION MEDICINES INC 0.77% 3.09%
VIR BIOTECHNOLOGY INC 0.67% 0.98%
STOKE THERAPEUTICS INC 0.65% 1.13%
INTELLIA THERAPEUTICS INC 0.59% 1.11%
WAVE LIFE SCIENCES LTD 0.63% 0.59%
BEAM THERAPEUTICS INC 0.59% 2.12%
REGENXBIO INC 0.97% 0.34%
ROCKET PHARMACEUTICALS INC 0.76% 0.30%
PRIME MEDICINE INC 0.70% 0.26%
Only in one fund ↓
Only in BBC
FIRST TRACKS BIOTHERAPEUTICS INC 1.67%
MBX BIOSCIENCES INC 1.24%
ATAIBECKLEY INC 1.23%
MONOPAR THERAPEUTICS INC 1.21%
DEFINIUM THERAPEUTICS INC 1.18%
XENCOR INC 1.10%
ZENAS BIOPHARMA INC 1.06%
APOGEE THERAPEUTICS INC 1.02%
Only in GNOM
MODERNA, INC. 7.50%
Twist Bioscience Corporation 6.34%
10x Genomics, Inc. 5.48%
GUARDANT HEALTH, INC. 5.28%
ILLUMINA, INC. 4.87%
NATERA, INC. 4.61%
Genscript Biotech Corp 3.81%
VERTEX PHARMACEUTICALS INCORPORATED 3.70%
Check overlap with more funds →

Window by window

Window by window: BBC vs GNOM: Holdings Overlap & Returns
Total return
WindowBBCGNOM
3 months−14.8%+24.5%
6 months−5.2%+49.4%
1 year+45.9%+66.6%
3 years+132.0%+81.6%
Since launchNot the same days: BBC Dec 2014 · GNOM Apr 2019+72.8%+16.0%

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Side by side

BBC Virtus Biotech Clinical Trials ETF · Holds 131 stocks in biotech, 0% of its weight in S&P 500 companies GNOM Global X Genomics & Biotechnology ETF · Holds 50 stocks in genomics and gene editing, 21% of its weight in S&P 500 companies
Theme Biotech Genomics and gene editing
In the S&P 500 0.0% 21.0%
Active share vs the S&P 500 100.0% 97.6%
In the Nasdaq-100 0.0% 5.3%
Holdings 131 50
Top ten, share of the fund 11.8% 48.8%
Expense ratio 0.65% 0.50%
Fee for the differing part 0.65% 0.51%
Total return, 1 year +45.9% +66.6%
vs its benchmark not measured not measured
Below its high −27.4% −36.2%
Net assets, BBC as of Jul 31, 2026 and GNOM as of Oct 12, 2026 $46m $104m

As of Nov 4, 2026. Source: ETFIQ.

6% of the two portfolios are the same securities at the same weight.

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About each fund
BBC

By weight, 0% of BBC's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 100%. The top ten holdings are 12% of the fund across 131 positions, as filed for Jul 31, 2026. Over the year to Nov 4, 2026 the fund returned +45.9% with distributions reinvested. It sits 27.4% below its all-time high of Feb 8, 2021.

GNOM

By weight, 21% of GNOM's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 98%. The top ten holdings are 49% of the fund across 50 positions, as filed for Aug 31, 2026. Over the year to Nov 4, 2026 the fund returned +66.6% with distributions reinvested. It sits 36.2% below its all-time high of Feb 8, 2021.

Questions people ask

Do BBC and GNOM hold the same stocks?
By their latest filings, 6% of their books are the same securities at the same weight. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBC or GNOM?
BBC has 0% of its weight in S&P 500 names and GNOM has 21%, so BBC differs more from the index.
Which is cheaper, BBC or GNOM?
BBC charges 0.65% a year and GNOM charges 0.50%, so GNOM is cheaper. Fees come from each fund's prospectus.
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ETFIQ, BBC against GNOM, data as of Nov 4, 2026. https://etfiq.com/compare/themes/bbc-vs-gnom

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