Data as of .
FBT vs GNMX: which is really different?
FBT and GNMX hold 24% of their weight in the same names.
ETFIQ Off-Index Score: GNMX scores higher
How much of it is not the index it is sold as an alternative to?
A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed
24% of the two portfolios are the same securities at the same weight.
What they hold in common
By the books each fund has filed, FBT and GNMX hold 24% of their money in the same securities at the same weight.
| Holding | FBT | GNMX |
|---|---|---|
| Illumina, Inc. | 3.90% | 4.36% |
| Vertex Pharmaceuticals Incorporated | 3.24% | 5.89% |
| Genmab A/S (ADR) | 3.71% | 2.91% |
| Incyte Corporation | 3.33% | 2.90% |
| Alnylam Pharmaceuticals, Inc. | 2.48% | 2.64% |
| BioMarin Pharmaceutical Inc. | 3.35% | 2.22% |
| Bio-Techne Corporation | 3.14% | 2.20% |
| NeoGenomics, Inc. | 4.37% | 1.60% |
| Veracyte, Inc. | 2.16% | 1.16% |
| Sarepta Therapeutics, Inc. | 3.29% | 0.93% |
| Only in FBT | Only in GNMX |
|---|---|
| Halozyme Therapeutics, Inc. 4.57% | Thermo Fisher Scientific Inc 8.62% |
| Natera, Inc. 4.24% | Moderna Inc 7.05% |
| Repligen Corporation 3.80% | Guardant Health Inc 3.86% |
| Corcept Therapeutics Inc. 3.72% | 10X Genomics Inc 3.42% |
| Regeneron Pharmaceuticals, Inc. 3.66% | Revolution Medicines Inc 3.27% |
| BeOne Medicines Ltd. (ADR) 3.64% | Twist Bioscience Corp 2.86% |
| Gilead Sciences, Inc. 3.58% | First American Government Obligations Fu 2.62% |
| argenx SE (ADR) 3.50% | Iovance Biotherapeutics Inc 2.30% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 18, 2026.
Performance, window by window
| Window | Total return | vs the S&P 500 | vs the Nasdaq-100 | |||
|---|---|---|---|---|---|---|
| FBT | GNMX | FBT | GNMX | FBT | GNMX | |
| 3 months | +17.2% | +29.7% | +14.9 pts | +27.4 pts | +19.6 pts | +32.2 pts |
| 6 months | +40.6% | not published | +22.6 pts | not published | +16.4 pts | not published |
| 1 year | +48.9% | not published | +32.3 pts | not published | +27.1 pts | not published |
| 3 years | +80.7% | not published | +2.3 pts | not published | −17.5 pts | not published |
| Since launch | +848.2% | +41.2% | +44.6 pts | +36.9 pts | −842.1 pts | +37.4 pts |
| FBT First Trust NYSE Arca Biotechnology Index Fund Holds 31 stocks in biotech, 24% of its weight in S&P 500 companies | GNMX Corgi Genomics & Precision Medicine ETF Holds 58 stocks in genomics and gene editing, 27% of its weight in S&P 500 companies | |
|---|---|---|
| Issuer | First Trust | Corgi |
| Theme | Biotech | Genomics and gene editing |
| In the S&P 500 | 23.6% | 26.7% |
| Active share vs the S&P 500 | 99.1% | 99.4% |
| In the Nasdaq-100 | 16.2% | 8.5% |
| Holdings | 31 | 58 |
| Top ten, share of the fund | 39.2% | 45.1% |
| Expense ratio | 0.55% | 0.35% |
| Fee for the differing part | 0.55% | 0.35% |
| Total return, 1 year | +48.9% | +41.2% (since launch on May 6, 2026) |
| vs the S&P 500 | +32.3 pts | +36.9 pts |
| vs the Nasdaq-100 | +27.1 pts | +37.4 pts |
| Below its high | −2.1% | −1.0% |
| Net assets | $2.9bn | $3m |
FBT in plain words
By weight, 24% of FBT's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 39% of the fund across 31 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +48.9% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 32.3 pts.
GNMX in plain words
By weight, 27% of GNMX's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 45% of the fund across 58 positions, as published by its issuer for Sep 18, 2026. Since it launched on May 6, 2026 the fund returned +41.2% with distributions reinvested against +4.3% for the S&P 500, so a holder was ahead by 36.9 pts.
Questions people ask
- Do FBT and GNMX hold the same stocks?
- By their latest filings, 24% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
- Which is more different from the S&P 500, FBT or GNMX?
- FBT has 24% of its weight in S&P 500 names and GNMX has 27%, so GNMX differs more from the index.
- Which is cheaper, FBT or GNMX?
- FBT charges 0.55% a year and GNMX charges 0.35%, so GNMX is cheaper. Fees come from each fund's prospectus.
Other comparisons
Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, FBT against GNMX, data as of Sep 18, 2026. https://etfiq.com/compare/themes/fbt-vs-gnmx Free to use with attribution; the underlying files are at Open data.