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Data as of .

BBP vs IDNA: which is really different?

BBP and IDNA hold 21% of their weight in the same names, and IDNA returned more over the year.

Virtus Biotech ETF and iShares Genomics Immunology and Healthcare ETF.

12.4%BBP in the S&P 500
23.9%IDNA in the S&P 500
+47.5%BBP total return, 1 year
+73.4%IDNA total return, 1 year

ETFIQ Off-Index Score: IDNA scores higher

How much of it is not the index it is sold as an alternative to?

BBP 61.7IDNA 64.10.1, the lowest in this set91.8, the highest

A percentile among the 379 thematic ETFs with a holdings filing. It is a position in a set, not a rating, and neither end of it is a recommendation. All thematic ETFs ranked by it · How it is computed

BBP88% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
12%88%inof its weight outside the S&P 500active share 99% · top ten 26% of the fund · 60 holdings filed Apr 30, 2026 · Nasdaq-100: 9% in12%88%inof its weight outside the S&P 500active share 99% · top ten 26% of the fund
IDNA76% of its weight is outside the S&P 500 · 1 year to Sep 18, 2026
24%76%in the S&P 500of its weight outside the S&P 500active share 99% · top ten 46% of the fund · 62 holdings filed Sep 17, 2026 · Nasdaq-100: 7% in24%76%inoutside the S&P 500active share 99% · top ten 46% of the fund

21% of the two portfolios are the same securities at the same weight.

What they hold in common

By the books each fund has filed, BBP and IDNA hold 21% of their money in the same securities at the same weight.

Positions BBP and IDNA both hold, largest shared weight first
HoldingBBPIDNA
IMMUNITYBIO INC4.83%2.94%
MODERNA INC2.50%9.54%
IOVANCE BIOTHERAPEUTICS INC2.45%3.67%
BIONTECH SE1.75%3.20%
EXELIXIS INC1.74%3.25%
INCYTE CORP1.60%3.60%
REGENERON PHARMACEUTICALS1.53%3.63%
VERTEX PHARMACEUTICALS INC1.52%3.34%
CRISPR THERAPEUTICS AG1.48%1.50%
NOVAVAX INC1.93%1.46%
KURA ONCOLOGY INC1.39%0.93%
NUVATION BIO INC0.85%1.33%
Only in each
Only in BBPOnly in IDNA
APELLIS PHARMACEUTICALS INC 2.60%TWIST BIOSCIENCE 7.09%
KALVISTA PHARMACEUTICALS INC 2.53%GENMAB 4.13%
MIRUM PHARMACEUTICALS INC 2.40%BAYER AG 3.87%
AXSOME THERAPEUTICS INC 2.25%REVOLUTION MEDICINES 3.76%
KINIKSA PHARMACEUTICALS INTERNATIONAL PL 2.07%TAKEDA PHARMACEUTICAL 3.62%
ROIVANT SCIENCES LTD 2.07%MERCK & CO INC 3.57%
ZAI LAB LTD 1.95%CARIS LIFE SCIENCES 3.39%
BIOCRYST PHARMACEUTICALS INC 1.94%ROCHE PS PAR AG 3.09%

Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Apr 30, 2026 and Sep 18, 2026.

Performance, window by window

BBP and IDNA over each window. Every figure is an ETFIQ calculation with distributions reinvested. Source: ETFIQ.
WindowTotal returnvs the S&P 500vs the Nasdaq-100
BBPIDNABBPIDNABBPIDNA
3 months+15.3%+30.3%+13.1 pts+28.1 pts+17.8 pts+32.8 pts
6 months+29.5%+41.4%+11.5 pts+23.4 pts+5.3 pts+17.2 pts
1 year+47.5%+73.4%+30.9 pts+56.9 pts+25.7 pts+51.7 pts
3 years+103.0%+91.3%+24.6 pts+12.9 pts+4.8 pts−6.9 pts
Since launch+304.4%+69.7%−56.6 pts−123.9 pts−371.1 pts−242.0 pts
Open the live comparison on ETFIQ
BBP and IDNA on the same fields, as of Sep 18, 2026. Source: ETFIQ.
BBP
Virtus Biotech ETF
Holds 60 stocks in biotech, 12% of its weight in S&P 500 companies
IDNA
iShares Genomics Immunology and Healthcare ETF
Holds 62 stocks in genomics and gene editing, 24% of its weight in S&P 500 companies
IssuerVirtusiShares
ThemeBiotechGenomics and gene editing
In the S&P 50012.4%23.9%
Active share vs the S&P 50099.0%99.1%
In the Nasdaq-1008.9%7.0%
Holdings6062
Top ten, share of the fund25.7%46.2%
Expense ratio0.34%0.47%
Fee for the differing part0.34%0.47%
Total return, 1 year+47.5%+73.4%
vs the S&P 500+30.9 pts+56.9 pts
vs the Nasdaq-100+25.7 pts+51.7 pts
Below its high−5.5%−24.7%
Net assets$59m$271m

BBP in plain words

By weight, 12% of BBP's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 26% of the fund across 60 positions, as filed for Apr 30, 2026. Over the year to Sep 18, 2026 the fund returned +47.5% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 30.9 pts. It sits 5.5% below its all-time high of Aug 19, 2026.

IDNA in plain words

By weight, 24% of IDNA's portfolio is stocks that are also in the S&P 500; its active share against the S&P 500 is 99%. The top ten holdings are 46% of the fund across 62 positions, as published by its issuer for Sep 18, 2026. Over the year to Sep 18, 2026 the fund returned +73.4% with distributions reinvested against +16.6% for the S&P 500, so a holder was ahead by 56.9 pts. It sits 24.7% below its all-time high of Sep 2, 2021.

Questions people ask

Do BBP and IDNA hold the same stocks?
By their latest filings, 21% of their books are the same securities at the same weight, which is a meaningful overlap. Overlap is the sum of the smaller weight of every security they share.
Which is more different from the S&P 500, BBP or IDNA?
BBP has 12% of its weight in S&P 500 names and IDNA has 24%, so IDNA differs more from the index.
Which is cheaper, BBP or IDNA?
BBP charges 0.34% a year and IDNA charges 0.47%, so BBP is cheaper. Fees come from each fund's prospectus.

Other comparisons

Where these figures came from

ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.

BBP against IDNA, ETFIQ, data as of Sep 18, 2026. Every figure is calculated from a named public source; the method is at etfiq.com/methodology. A comparison is not a recommendation.

Cite this page. ETFIQ, BBP against IDNA, data as of Sep 18, 2026. https://etfiq.com/compare/themes/bbp-vs-idna Free to use with attribution; the underlying files are at Open data.

How every figure is computed · Standards and sources