Data as of Sep 13, 2026. Both funds on the fields they both publish, from the same sources.
RSP vs XBI: how they differ
RSP and XBI hold 2% of their weight in the same names, and XBI returned more over the year.
Invesco S&P 500 Equal Weight ETF and State Street(R) SPDR(R) S&P(R) Biotech ETF.
What they hold in common
By the books each fund has filed, RSP and XBI hold 2% of their money in the same securities at the same weight.
| Holding | RSP | XBI |
|---|---|---|
| Moderna Inc | 0.58% | 2.87% |
| Regeneron Pharmaceuticals Inc | 0.26% | 1.27% |
| Gilead Sciences Inc | 0.23% | 1.15% |
| Vertex Pharmaceuticals Inc | 0.23% | 1.14% |
| Incyte Corp | 0.23% | 1.13% |
| Amgen Inc | 0.22% | 1.09% |
| AbbVie Inc | 0.22% | 1.09% |
| Biogen Inc | 0.21% | 1.07% |
| Only in RSP | Only in XBI |
|---|---|
| Veeva Systems Inc 0.31% | TWIST BIOSCIENCE CORP 1.81% |
| Zebra Technologies Corp 0.31% | HALOZYME THERAPEUTICS INC 1.47% |
| Marathon Petroleum Corp 0.29% | NATERA INC 1.46% |
| Valero Energy Corp 0.29% | KYMERA THERAPEUTICS INC 1.45% |
| Charles River Laboratories International 0.28% | TRAVERE THERAPEUTICS INC 1.40% |
| Phillips 66 0.28% | ROIVANT SCIENCES LTD 1.39% |
| Salesforce Inc 0.28% | ORUKA THERAPEUTICS INC 1.38% |
| Global Payments Inc 0.28% | REVOLUTION MEDICINES INC 1.36% |
Weight overlap is an ETFIQ calculation: for every security both funds hold, the smaller of the two weights, summed. Above 50%, holding both is close to holding one of them twice. Holdings dated Sep 10, 2026.
| RSP Invesco S&P 500 Equal Weight ETF | XBI State Street(R) SPDR(R) S&P(R) Biotech ETF | |
|---|---|---|
| Where it sits | Core index fund | Core index fund |
| Issuer | Invesco | State Street |
| What it is | S&P 500 equal weight | SPDR S&P Biotech |
| Total return, 1 year | +14.8% | +64.0% |
| S&P 500 over the same days | +17.5% | +17.5% |
| Gap to the S&P 500 | −2.7 pts | +46.5 pts |
| Expense ratio | 0.20% | 0.35% |
| Already in the S&P 500 | 99.1% | 8.5% |
| Holdings | 506 | 154 |
RSP in plain words
RSP is an index equity fund tracking the S&P 500 equal weight. Over the year to Sep 11, 2026 it returned +14.8% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.20% a year. By its holdings filed for Sep 10, 2026, 99% of the fund by weight is stocks the S&P 500 also holds, across 506 positions, with the top ten at 3.2%. It sat 3.5% below its high of Aug 14, 2026 on Sep 11, 2026.
XBI in plain words
XBI is an index equity fund tracking the SPDR S&P Biotech. Over the year to Sep 11, 2026 it returned +64.0% with distributions reinvested, against +17.5% for the S&P 500 and +23.0% for the Nasdaq-100. The prospectus expense ratio is 0.35% a year. By its holdings filed for Sep 10, 2026, 8% of the fund by weight is stocks the S&P 500 also holds, across 154 positions, with the top ten at 15.9%. It sat 9.6% below its high of Feb 8, 2021 on Sep 11, 2026.
Questions people ask
- Which returned more over the last year, RSP or XBI?
- In the year to Sep 13, 2026, with distributions reinvested, RSP returned +14.8% and XBI returned +64.0%, so XBI returned more. One year is one year; the longer windows are in the table.
- Which is cheaper, RSP or XBI?
- RSP charges 0.20% a year and XBI charges 0.35%, so RSP is cheaper. Fees come from each fund's prospectus.
- How much do RSP and XBI overlap with the S&P 500?
- By their latest filed holdings, 99% of RSP and 8% of XBI by weight is stocks the S&P 500 already holds. Between the two funds, 2% of their books are the same securities at the same weight.
Other comparisons
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Where these figures came from
ETFIQ links to the documents behind every figure. It is not affiliated with any issuer, and a link is not an endorsement.
Cite this page. ETFIQ, RSP against XBI, data as of Sep 13, 2026. https://etfiq.com/compare/any/rsp-vs-xbi Free to use with attribution; the underlying files are at Open data.
A comparison is not a recommendation. Standards and sources